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"charge":0.0,
"formula":"C8H15N3O4",
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},
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"sbo":"SBO:0000247"
}
},
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"id":"__LactoPanGEM__ala_his_c",
"name":"Ala-His",
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"charge":0.0,
"formula":"C9H14N4O3",
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},
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"sbo":"SBO:0000247"
}
},
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"id":"__LactoPanGEM__ala_his_e",
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"charge":0.0,
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},
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"sbo":"SBO:0000247"
}
},
{
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"charge":0.0,
"formula":"C9H18N2O3",
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},
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"sbo":"SBO:0000247"
}
},
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"charge":0.0,
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},
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"sbo":"SBO:0000247"
}
},
{
"id":"alac__S_c:-1",
"name":"(2S)-2-hydroxy-2-methyl-3-oxobutanoate",
"compartment":"c",
"charge":-1.0,
"formula":"C5H7O4",
"notes":{
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"InChIString":"NMDWGEGFJUBKLB-YFKPBYRVSA-M"
},
"annotation":{
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"chebi":[
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"kegg.compound":"C06010",
"pubchem.compound":"8282",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__alac__S_DUP3_c",
"name":"",
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"charge":-1.0,
"formula":"C5H7O4",
"notes":{
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"annotation":{
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"kegg.compound":"C00900",
"pubchem.compound":"22",
"sbo":"SBO:0000247"
}
},
{
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"name":"D-Alanyl-D-lactate",
"compartment":"c",
"charge":0.0,
"formula":"C6H11NO4",
"annotation":{
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"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__alatrna_c",
"name":"L-Alanyl-tRNA(Ala)",
"compartment":"c",
"charge":1.0,
"formula":"C3H6NOR",
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},
"annotation":{
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"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__alcopde_c",
"name":"Alcophosphamide",
"compartment":"c",
"charge":0.0,
"formula":"C7H17Cl2N2O3P",
"notes":{
"InChIString":"BZGFIGVSVQRQBJ-UHFFFAOYSA-N"
},
"annotation":{
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"kegg.compound":"C16551",
"pubchem.compound":"98612",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__aldpham_c",
"name":"Aldophosphamide",
"compartment":"c",
"charge":0.0,
"formula":"C7H15Cl2N2O3P",
"notes":{
"InChIString":"QMGUSPDJTPDFSF-UHFFFAOYSA-N"
},
"annotation":{
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"kegg.compound":"C07645",
"pubchem.compound":"107744",
"sbo":"SBO:0000247"
}
},
{
"id":"allphn_c",
"name":"urea-1-carboxylate",
"compartment":"c",
"charge":-1.0,
"formula":"C2H3N2O3",
"notes":{
"InChIString":"AVWRKZWQTYIKIY-UHFFFAOYSA-M"
},
"annotation":{
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"chebi":[
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"kegg.compound":"C01010",
"pubchem.compound":"150833",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__alltn_e",
"name":"Allantoin",
"compartment":"e",
"charge":0.0,
"formula":"C4H5N4O3",
"notes":{
"InChIString":"POJWUDADGALRAB-UHFFFAOYSA-N"
},
"annotation":{
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"kegg.compound":"C01551",
"pubchem.compound":"204",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__alpro_c",
"name":"S-Aminomethyldihydrolipoylprotein",
"compartment":"c",
"charge":1.0,
"formula":"C2H7NRS2",
"annotation":{
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"kegg.compound":"C01242",
"sbo":"SBO:0000247"
}
},
{
"id":"amet_c",
"name":"(S)-S-adenosyl-L-methionine",
"compartment":"c",
"charge":1.0,
"formula":"C15H23N6O5S",
"notes":{
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},
"annotation":{
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"chebi":[
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"kegg.compound":"C00019",
"pubchem.compound":"34755",
"sbo":"SBO:0000247"
}
},
{
"id":"amp_c",
"name":"adenosine 5'-monophosphate(2-)",
"compartment":"c",
"charge":-2.0,
"formula":"C10H12N5O7P",
"notes":{
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},
"annotation":{
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"kegg.compound":"C00020",
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}
},
{
"id":"amp_e",
"name":"adenosine 5'-monophosphate(2-)",
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"charge":-2.0,
"formula":"C10H12N5O7P",
"notes":{
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"annotation":{
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"kegg.compound":"C00020",
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},
{
"id":"ans_c",
"name":"anserine",
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"charge":0.0,
"formula":"C10H16N4O3",
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"kegg.compound":"C01262",
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}
},
{
"id":"__LactoPanGEM__anteiluc24_c",
"name":"Anteisoheptadecanoyllipoteichoic acid (n-24), linked, unsubstituted",
"compartment":"c",
"charge":-24.0,
"formula":"C121H236O135P24",
"annotation":{
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"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__anteinsu24_c",
"name":"Anteisopentadecanoyllipoteichoic acid (n-24), linked, glucose substituted",
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"charge":-24.0,
"formula":"C261H468O255P24",
"annotation":{
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"sbo":"SBO:0000247"
}
},
{
"id":"anth_c",
"name":"anthranilate",
"compartment":"c",
"charge":-1.0,
"formula":"C7H6NO2",
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},
"annotation":{
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"kegg.compound":"C00108",
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}
},
{
"id":"__LactoPanGEM__apoacp_c",
"name":"Apo-ACP",
"compartment":"c",
"charge":0.0,
"formula":"HOR",
"annotation":{
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"kegg.compound":"C03688",
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}
},
{
"id":"__LactoPanGEM__aproa_c",
"name":"3-Aminopropanal",
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"charge":1.0,
"formula":"C3H8NO",
"notes":{
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},
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"kegg.compound":"C05665",
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}
},
{
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"name":"aldehydo-L-arabinose",
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"charge":0.0,
"formula":"C5H10O5",
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},
{
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"charge":0.0,
"formula":"C5H10O5",
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},
{
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"charge":-1.0,
"formula":"C20H31O2",
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"kegg.compound":"C00219",
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},
{
"id":"arbt6p_c",
"name":"arbutin 6-phosphate(2-)",
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"charge":-2.0,
"formula":"C12H15O10P",
"notes":{
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},
{
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"name":"hydroquinone O-beta-D-glucopyranoside",
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"charge":0.0,
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},
{
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"charge":1.0,
"formula":"C6H15N4O2",
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},
{
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},
{
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"name":"(N(omega)-L-arginino)succinate(1-)",
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"charge":-1.0,
"formula":"C10H17N4O6",
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},
{
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"charge":2.0,
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},
{
"id":"__LactoPanGEM__arsenb_c",
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"charge":0.0,
"formula":"C5H11AsO2",
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},
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}
},
{
"id":"__LactoPanGEM__arsenb_e",
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"charge":0.0,
"formula":"C5H11AsO2",
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},
{
"id":"__LactoPanGEM__ascb6p_c",
"name":"L-ascorbate-6-phosphate",
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"charge":-2.0,
"formula":"C6H7O9P",
"annotation":{
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"sbo":"SBO:0000247"
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},
{
"id":"__LactoPanGEM__ascb__L_e",
"name":"L-Ascorbate",
"compartment":"e",
"charge":-1.0,
"formula":"C6H8O6",
"annotation":{
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"sbo":"SBO:0000247"
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},
{
"id":"asn__L_c",
"name":"L-asparagine",
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"charge":0.0,
"formula":"C4H8N2O3",
"notes":{
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},
"annotation":{
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"kegg.compound":"C00152",
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},
{
"id":"asn__L_e",
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"charge":0.0,
"formula":"C4H8N2O3",
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},
{
"id":"__LactoPanGEM__asntrna_c",
"name":"L-Asparaginyl-tRNA(Asn)",
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"charge":1.0,
"formula":"C14H24N2O12PR2",
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},
{
"id":"__LactoPanGEM__aso3_c",
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"charge":-1.0,
"formula":"AsO3",
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},
{
"id":"__LactoPanGEM__arsna_c",
"name":"Arsenate",
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"charge":-2.0,
"formula":"AsO4",
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},
{
"id":"asp__D_c",
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"charge":-1.0,
"formula":"C4H6NO4",
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},
{
"id":"asp__L_c",
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"charge":-1.0,
"formula":"C4H6NO4",
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},
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},
{
"id":"aspsa_c",
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"charge":0.0,
"formula":"C4H7NO3",
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},
{
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},
{
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},
{
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},
{
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"charge":1.0,
"formula":"C5H12NO",
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},
{
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"charge":0.0,
"formula":"C2H5N3O2",
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},
{
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"charge":0.0,
"formula":"C4H8O",
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},
{
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"name":"butyryl-CoA(4-)",
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"charge":-4.0,
"formula":"C25H38N7O17P3S",
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},
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},
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},
{
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},
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},
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}
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}
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},
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},
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},
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},
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},
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},
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},
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},
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},
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},
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},
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},
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},
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},
{
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},
{
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},
{
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}
},
{
"id":"__LactoPanGEM__gly_leu_e",
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}
},
{
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},
{
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},
{
"id":"__LactoPanGEM__gly_phe_c",
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},
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},
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},
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},
{
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},
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},
{
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},
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},
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},
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},
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},
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},
{
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},
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},
{
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},
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},
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},
{
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},
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},
{
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},
{
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}
},
{
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},
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},
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},
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},
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},
{
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},
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},
{
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},
{
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},
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},
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},
{
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},
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},
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},
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},
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},
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},
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},
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{
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},
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},
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}
},
{
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"name":"Holo[acp]",
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"formula":"R",
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}
},
{
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"charge":-1.0,
"formula":"CHO3",
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},
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"kegg.compound":"C00288",
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}
},
{
"id":"hcys__L_c",
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"charge":0.0,
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},
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"kegg.compound":"C00155",
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}
},
{
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"charge":-1.0,
"formula":"C16H31O2",
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},
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}
},
{
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},
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}
},
{
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},
{
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}
},
{
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}
},
{
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},
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}
},
{
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}
},
{
"id":"__LactoPanGEM__hexdp_c",
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},
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}
},
{
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},
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}
},
{
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"formula":"Hg",
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},
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"kegg.compound":"C00703",
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}
},
{
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},
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}
},
{
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},
{
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},
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}
},
{
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},
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},
{
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},
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}
},
{
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},
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}
},
{
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}
},
{
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}
},
{
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}
},
{
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}
},
{
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},
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},
{
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}
},
{
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},
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}
},
{
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},
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}
},
{
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}
},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
{
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},
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},
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},
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},
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{
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},
{
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},
{
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{
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},
{
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"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__valtrna_c",
"name":"L-Valyl-tRNA(Val)",
"compartment":"c",
"charge":1.0,
"formula":"C5H10NOR",
"notes":{
"ChEBIID":"CHEBI:13187, CHEBI:29164, CHEBI:6322"
},
"annotation":{
"biggr":"__LactoPanGEM__valtrna_c:1",
"kegg.compound":"C02554",
"sbo":"SBO:0000247"
}
},
{
"id":"xan_c",
"name":"7H-xanthine",
"compartment":"c",
"charge":0.0,
"formula":"C5H4N4O2",
"notes":{
"InChIString":"LRFVTYWOQMYALW-UHFFFAOYSA-N"
},
"annotation":{
"biggr":"xan_c:0",
"chebi":[
"CHEBI:17712",
"CHEBI:48517"
],
"kegg.compound":"C00385",
"pubchem.compound":"1188",
"sbo":"SBO:0000247"
}
},
{
"id":"xan_e",
"name":"7H-xanthine",
"compartment":"e",
"charge":0.0,
"formula":"C5H4N4O2",
"notes":{
"InChIString":"LRFVTYWOQMYALW-UHFFFAOYSA-N"
},
"annotation":{
"biggr":"xan_e:0",
"chebi":[
"CHEBI:17712",
"CHEBI:48517"
],
"kegg.compound":"C00385",
"pubchem.compound":"1188",
"sbo":"SBO:0000247"
}
},
{
"id":"xmp_c",
"name":"5'-xanthylate(2-)",
"compartment":"c",
"charge":-2.0,
"formula":"C10H11N4O9P",
"notes":{
"InChIString":"DCTLYFZHFGENCW-UUOKFMHZSA-L"
},
"annotation":{
"biggr":"xmp_c:-2",
"chebi":[
"CHEBI:57464"
],
"kegg.compound":"C00655",
"pubchem.compound":"73323",
"sbo":"SBO:0000247"
}
},
{
"id":"xol7ah2al_c",
"name":"3alpha,7alpha-dihydroxy-5beta-cholestan-26-al",
"compartment":"c",
"charge":0.0,
"formula":"C27H46O3",
"notes":{
"InChIString":"YWGOKHMOJTZGBN-UGMUFZQESA-N",
"PubChemID":"440673\u00a05118584\u00a05460041"
},
"annotation":{
"biggr":"xol7ah2al_c:0",
"chebi":[
"CHEBI:27428"
],
"kegg.compound":"C05445",
"sbo":"SBO:0000247"
}
},
{
"id":"xol7ah3_c",
"name":"5beta-cholestane-3alpha,7alpha,26-triol",
"compartment":"c",
"charge":0.0,
"formula":"C27H48O3",
"notes":{
"InChIString":"OQIJRBFRXGIHMI-UGMUFZQESA-N",
"PubChemID":"440672\u00a03082089\u00a05118583\u00a05284190\u00a05284294"
},
"annotation":{
"biggr":"xol7ah3_c:0",
"chebi":[
"CHEBI:28540"
],
"kegg.compound":"C05444",
"sbo":"SBO:0000247"
}
},
{
"id":"xtp_c",
"name":"XTP(4-)",
"compartment":"c",
"charge":-4.0,
"formula":"C10H11N4O15P3",
"notes":{
"ChEBIID":"10049",
"InChIString":"CAEFEWVYEZABLA-UUOKFMHZSA-K"
},
"annotation":{
"biggr":"xtp_c:-4",
"chebi":[
"CHEBI:61314"
],
"kegg.compound":"C00700",
"pubchem.compound":"3968",
"sbo":"SBO:0000247"
}
},
{
"id":"xtsn_c",
"name":"xanthosine",
"compartment":"c",
"charge":0.0,
"formula":"C10H12N4O6",
"notes":{
"InChIString":"UBORTCNDUKBEOP-UUOKFMHZSA-N"
},
"annotation":{
"biggr":"xtsn_c:0",
"chebi":[
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],
"kegg.compound":"C01762",
"pubchem.compound":"64959",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__xu1p__L_c",
"name":"L-Xylulose 1-phosphate",
"compartment":"c",
"charge":-2.0,
"formula":"C5H9O8P",
"notes":{
"InChIString":"NBOCCPQHBPGYCX-WVZVXSGGSA-L",
"PubChemID":"441020\u00a05229252"
},
"annotation":{
"biggr":"__LactoPanGEM__xu1p__L_c:-2",
"kegg.compound":"C06441",
"sbo":"SBO:0000247"
}
},
{
"id":"xu5p__D_c",
"name":"D-xylulose 5-phosphate(2-)",
"compartment":"c",
"charge":-2.0,
"formula":"C5H9O8P",
"notes":{
"InChIString":"FNZLKVNUWIIPSJ-RFZPGFLSSA-L"
},
"annotation":{
"biggr":"xu5p__D_c:-2",
"chebi":[
"CHEBI:57737"
],
"kegg.compound":"C00231",
"pubchem.compound":"439190",
"sbo":"SBO:0000247"
}
},
{
"id":"xu5p__L_c",
"name":"L-xylulose 5-phosphate(2-)",
"compartment":"c",
"charge":-2.0,
"formula":"C5H9O8P",
"notes":{
"InChIString":"FNZLKVNUWIIPSJ-WHFBIAKZSA-L"
},
"annotation":{
"biggr":"xu5p__L_c:-2",
"chebi":[
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],
"kegg.compound":"C03291",
"pubchem.compound":"850",
"sbo":"SBO:0000247"
}
},
{
"id":"xyl__D_e",
"name":"D-xylopyranose",
"compartment":"e",
"charge":0.0,
"formula":"C5H10O5",
"notes":{
"InChIString":"SRBFZHDQGSBBOR-LECHCGJUSA-N"
},
"annotation":{
"biggr":"xyl__D_e:0",
"chebi":[
"CHEBI:53455"
],
"kegg.compound":"C00181",
"pubchem.compound":"135191",
"sbo":"SBO:0000247"
}
},
{
"id":"xylt_c",
"name":"xylitol",
"compartment":"c",
"charge":0.0,
"formula":"C5H12O5",
"notes":{
"InChIString":"HEBKCHPVOIAQTA-SCDXWVJYSA-N"
},
"annotation":{
"biggr":"xylt_c:0",
"chebi":[
"CHEBI:17151"
],
"kegg.compound":"C00379",
"pubchem.compound":"827",
"sbo":"SBO:0000247"
}
},
{
"id":"xylu__D_c",
"name":"D-xylulose",
"compartment":"c",
"charge":0.0,
"formula":"C5H10O5",
"notes":{
"InChIString":"ZAQJHHRNXZUBTE-WUJLRWPWSA-N"
},
"annotation":{
"biggr":"xylu__D_c:0",
"chebi":[
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],
"kegg.compound":"C00310",
"pubchem.compound":"439204",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__zn_c",
"name":"Zn2+",
"compartment":"c",
"charge":2.0,
"formula":"Zn",
"notes":{
"InChIString":"PTFCDOFLOPIGGS-UHFFFAOYSA-N"
},
"annotation":{
"biggr":"__LactoPanGEM__zn_c:2",
"kegg.compound":"C00038",
"pubchem.compound":"23994",
"sbo":"SBO:0000247"
}
},
{
"id":"__LactoPanGEM__zn_e",
"name":"Zn2+",
"compartment":"e",
"charge":2.0,
"formula":"Zn",
"notes":{
"InChIString":"PTFCDOFLOPIGGS-UHFFFAOYSA-N"
},
"annotation":{
"biggr":"__LactoPanGEM__zn_e:2",
"kegg.compound":"C00038",
"pubchem.compound":"23994",
"sbo":"SBO:0000247"
}
},
{
"id":"zymst_c",
"name":"zymosterol",
"compartment":"c",
"charge":0.0,
"formula":"C27H44O",
"notes":{
"InChIString":"CGSJXLIKVBJVRY-LVKDPOMLSA-N"
},
"annotation":{
"biggr":"zymst_c:0",
"chebi":[
"CHEBI:18252"
],
"kegg.compound":"C05437",
"pubchem.compound":"92746",
"sbo":"SBO:0000247"
}
}
],
"reactions":[
{
"id":"ADSL1r",
"name":"adenylsuccinate lyase",
"metabolites":{
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"dcamp_c":-1.0,
"fum_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21510",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ADSL1r",
"rhea":"RHEA:16853",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ASPK_1",
"name":"aspartate kinase",
"metabolites":{
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"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"asp__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05300 or KJMKFHIL_06240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CYTK2_1",
"name":"Cytidylate Kinase (dCMP)",
"metabolites":{
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"__LactoPanGEM__dcdp_c":1.0,
"dcmp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYTK2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DADK_1",
"name":"Deoxyadenylate kinase",
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dadp_c":1.0,
"damp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DADK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DGK1_1",
"name":"Deoxyguanylate Kinase (dGMP:ATP)",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dgdp_c":1.0,
"dgmp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17870 or KJMKFHIL_00780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DGK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DHFR",
"name":"dihydrofolate reductase",
"metabolites":{
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"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"thf_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHFR",
"rhea":"RHEA:15009",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DTMPK_1",
"name":"DTMP kinase",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dtdp_c":1.0,
"dtmp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16220",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__DTMPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"E4PD",
"name":"Erythrose 4-phosphate dehydrogenase",
"metabolites":{
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"e4p_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08640 or KJMKFHIL_03110",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"E4PD",
"rhea":"RHEA:12056",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G6PDH2r_1",
"name":"Glucose 6-phosphate dehydrogenase",
"metabolites":{
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"__LactoPanGEM__g6p_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13420",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__G6PDH2r_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GALKr_1",
"name":"Galactokinase",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gal1p__D_c":1.0,
"gal_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15470 or KJMKFHIL_09810",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GALKr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"MALTATr",
"name":"maltose O-acetyltransferase",
"metabolites":{
"accoa_c":-1.0,
"acmalt_c":1.0,
"coa_c":1.0,
"malt_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24320 or KJMKFHIL_05320 or KJMKFHIL_27120",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MALTATr",
"rhea":"RHEA:10456",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK4",
"name":"Nucleoside-Diphosphate Kinase (ATP:dTDP)",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dtdp_c":-1.0,
"__LactoPanGEM__dttp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK4:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK7",
"name":"Nucleoside-Diphosphate Kinase (ATP:dCDP)",
"metabolites":{
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"__LactoPanGEM__dcdp_c":-1.0,
"__LactoPanGEM__dctp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK7:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGK_1",
"name":"Phosphoglycerate Kinase",
"metabolites":{
"13dpg_c":-1.0,
"3pg_c":1.0,
"__LactoPanGEM__adp_c":-1.0,
"__LactoPanGEM__atp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03100",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__PGK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRAGSr_1",
"name":"Phosphoribosylglycinamide synthase",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"gar_c":1.0,
"gly_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"pram_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01950",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__PRAGSr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP7",
"name":"purine-nucleoside phosphorylase (Xanthosine)",
"metabolites":{
"pi_c":-1.0,
"r1p_c":1.0,
"xan_c":1.0,
"xtsn_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP7",
"sbo":"SBO:0000176"
}
},
{
"id":"SHK3Dr",
"name":"shikimate dehydrogenase",
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"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"skm_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24370 or KJMKFHIL_24390",
"notes":{
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},
"annotation":{
"biggr":"SHK3Dr",
"rhea":"RHEA:17737",
"sbo":"SBO:0000176"
}
},
{
"id":"TGBPA",
"name":"Tagatose-bisphosphate aldolase",
"metabolites":{
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"g3p_c":1.0,
"tagdp__D_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19010 or KJMKFHIL_15340",
"notes":{
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},
"annotation":{
"biggr":"TGBPA",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__URIDK2r_1",
"name":"Uridylate kinase (dUMP)",
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"__LactoPanGEM__dudp_c":1.0,
"dump_c":-1.0
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"gene_reaction_rule":"KJMKFHIL_00320",
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},
"annotation":{
"biggr":"__LactoPanGEM__URIDK2r_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR100_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C10:0)",
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"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__3OAR100_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR120_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C12:0)",
"metabolites":{
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"h_c":-1.0,
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"nadph_c":-1.0
},
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"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
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},
"annotation":{
"biggr":"__LactoPanGEM__3OAR120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR140_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C14:0)",
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"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
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"annotation":{
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"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR160_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C16:0)",
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"lower_bound":-1000.0,
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"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__3OAR160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR40_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C4:0)",
"metabolites":{
"__LactoPanGEM__3haacp_c":1.0,
"__LactoPanGEM__actacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR40_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR60_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C6:0)",
"metabolites":{
"__LactoPanGEM__3hhexacp_c":1.0,
"__LactoPanGEM__3ohexacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR60_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR80_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C8:0)",
"metabolites":{
"__LactoPanGEM__3hoctacp_c":1.0,
"__LactoPanGEM__3ooctacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR80_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ACALD",
"name":"acetaldehyde dehydrogenase (acetylating)",
"metabolites":{
"acald_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACALD",
"rhea":"RHEA:23288",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACKr_1",
"name":"acetate kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"ac_c":-1.0,
"actp_c":1.0
},
"lower_bound":-3.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04720 or KJMKFHIL_06380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACKr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ACOTA",
"name":"acetylornithine transaminase",
"metabolites":{
"acg5sa_c":1.0,
"acorn_c":-1.0,
"akg_c":-1.0,
"glu__L_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02390 or KJMKFHIL_10690",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACOTA",
"rhea":"RHEA:18049",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ADK1_1",
"name":"Adenylate Kinase",
"metabolites":{
"__LactoPanGEM__adp_c":2.0,
"__LactoPanGEM__atp_c":-1.0,
"amp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ADSL2r_1",
"name":"Adenylosuccinate lyase",
"metabolites":{
"__LactoPanGEM__25aics_c":-1.0,
"aicar_c":1.0,
"fum_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21510",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADSL2r_1",
"sbo":"SBO:0000176"
}
},
{
"id":"AICART",
"name":"phosphoribosylaminoimidazolecarboxamide formyltransferase",
"metabolites":{
"10fthf_c":-1.0,
"aicar_c":-1.0,
"fprica_c":1.0,
"thf_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AICART",
"rhea":"RHEA:22192",
"sbo":"SBO:0000176"
}
},
{
"id":"ALAR",
"name":"alanine racemase",
"metabolites":{
"ala__D_c":1.0,
"ala__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22270 or KJMKFHIL_23190",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALAR",
"rhea":"RHEA:20249",
"sbo":"SBO:0000176"
}
},
{
"id":"ALCD19",
"name":"alcohol dehydrogenase (glycerol)",
"metabolites":{
"glyald_c":-1.0,
"glyc_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALCD19",
"rhea":"RHEA:30027",
"sbo":"SBO:0000176"
}
},
{
"id":"ARGSL",
"name":"argininosuccinate lyase",
"metabolites":{
"arg__L_c":1.0,
"argsuc_c":-1.0,
"fum_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ARGSL",
"rhea":"RHEA:24020",
"sbo":"SBO:0000176"
}
},
{
"id":"ASAD",
"name":"aspartate-semialdehyde dehydrogenase",
"metabolites":{
"4pasp_c":1.0,
"aspsa_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0,
"pi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASAD",
"rhea":"RHEA:24284",
"sbo":"SBO:0000176"
}
},
{
"id":"ASPTA",
"name":"aspartate transaminase",
"metabolites":{
"akg_c":-1.0,
"asp__L_c":-1.0,
"glu__L_c":1.0,
"oaa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22520 or KJMKFHIL_06290 or KJMKFHIL_26420 or KJMKFHIL_09860 or KJMKFHIL_03830",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASPTA",
"rhea":"RHEA:21824",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CBIAT",
"name":"Cobinamide adenyltransferase",
"metabolites":{
"__LactoPanGEM__adocbi_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"cbi_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0,
"ppi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CBIAT",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CBLAT",
"name":"cob(I)alamin adenosyltransferase",
"metabolites":{
"__LactoPanGEM__adocbl_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pppi_c":1.0,
"cbl1_c":-1.0,
"h_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CBLAT",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CYTK1_1",
"name":"Cytidylate Kinase (CMP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__cdp_c":1.0,
"cmp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYTK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DAPE",
"name":"diaminopimelate epimerase",
"metabolites":{
"26dap_LL_c":-1.0,
"26dap__M_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DAPE",
"rhea":"RHEA:15393",
"sbo":"SBO:0000176"
}
},
{
"id":"DDPGALA",
"name":"2-dehydro-3-deoxy-6-phosphogalactonate aldolase",
"metabolites":{
"2dh3dgal6p_c":-1.0,
"g3p_c":1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DDPGALA",
"sbo":"SBO:0000176"
}
},
{
"id":"DHORTS",
"name":"dihydroorotase",
"metabolites":{
"cbasp_c":1.0,
"dhor__S_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHORTS",
"rhea":"RHEA:24296",
"sbo":"SBO:0000176"
}
},
{
"id":"DURIPP_1",
"name":"deoxyuridine phosphorylase",
"metabolites":{
"2dr1p_c":1.0,
"duri_c":-1.0,
"pi_c":-1.0,
"ura_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DURIPP_1",
"rhea":"RHEA:22824",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ECOAH1_1",
"name":"3-hydroxyacyl-CoA dehydratase (3-hydroxybutanoyl-CoA)",
"metabolites":{
"3hpcoa_c":-1.0,
"b2coa_c":1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ECOAH1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ENO",
"name":"enolase",
"metabolites":{
"2pg_c":-1.0,
"h2o_c":1.0,
"pep_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03080 or KJMKFHIL_21030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ENO",
"rhea":"RHEA:10164",
"sbo":"SBO:0000176"
}
},
{
"id":"F6PA",
"name":"fructose 6-phosphate aldolase",
"metabolites":{
"dha_c":1.0,
"f6p_c":-1.0,
"g3p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12210",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"F6PA",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FBA_1",
"name":"Fructose-Bisphosphate Aldolase",
"metabolites":{
"__LactoPanGEM__f26bp_c":-1.0,
"dhap_c":1.0,
"g3p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25460 or KJMKFHIL_17160 or KJMKFHIL_11840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FBA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"FCLPA",
"name":"L-fuculose 1-phosphate aldolase",
"metabolites":{
"dhap_c":1.0,
"fc1p_c":-1.0,
"lald__L_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19360",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FCLPA",
"rhea":"RHEA:12933",
"sbo":"SBO:0000176"
}
},
{
"id":"FUM",
"name":"fumarase",
"metabolites":{
"fum_c":-1.0,
"h2o_c":-1.0,
"mal__L_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FUM",
"rhea":"RHEA:12460",
"sbo":"SBO:0000176"
}
},
{
"id":"G3PD2",
"name":"glycerol-3-phosphate dehydrogenase (NADP)",
"metabolites":{
"dhap_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G3PD2",
"rhea":"RHEA:11096",
"sbo":"SBO:0000176"
}
},
{
"id":"GAPD",
"name":"glyceraldehyde-3-phosphate dehydrogenase",
"metabolites":{
"13dpg_c":1.0,
"g3p_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"pi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08640 or KJMKFHIL_03110",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GAPD",
"sbo":"SBO:0000176"
}
},
{
"id":"GARFT",
"name":"phosphoribosylglycinamide formyltransferase",
"metabolites":{
"10fthf_c":-1.0,
"fgam_c":1.0,
"gar_c":-1.0,
"h_c":1.0,
"thf_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GARFT",
"rhea":"RHEA:15053",
"sbo":"SBO:0000176"
}
},
{
"id":"GHMT2r",
"name":"glycine hydroxymethyltransferase, reversible",
"metabolites":{
"gly_c":1.0,
"h2o_c":1.0,
"mlthf_c":1.0,
"ser__L_c":-1.0,
"thf_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GHMT2r",
"rhea":"RHEA:15481",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GK1_1",
"name":"Guanylate Kinase (GMP:ATP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gdp_c":1.0,
"gmp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17870 or KJMKFHIL_00780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GLUDy_1",
"name":"glutamate dehydrogenase (NADP)",
"metabolites":{
"akg_c":1.0,
"glu__L_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0,
"nh4_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLUDy_1",
"rhea":"RHEA:11612",
"sbo":"SBO:0000176"
}
},
{
"id":"GLUR",
"name":"glutamate racemase",
"metabolites":{
"glu__D_c":-1.0,
"glu__L_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLUR",
"rhea":"RHEA:12813",
"sbo":"SBO:0000176"
}
},
{
"id":"H2CO3D",
"name":"HCO3 equilibration reaction",
"metabolites":{
"co2_c":1.0,
"h2co3_c":-1.0,
"h2o_c":1.0,
"h_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"H2CO3D",
"rhea":"RHEA:10748",
"sbo":"SBO:0000176"
}
},
{
"id":"HSDy",
"name":"homoserine dehydrogenase (NADPH)",
"metabolites":{
"aspsa_c":1.0,
"h_c":1.0,
"hom__L_c":-1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HSDy",
"rhea":"RHEA:15761",
"sbo":"SBO:0000176"
}
},
{
"id":"ILETA",
"name":"isoleucine transaminase",
"metabolites":{
"3mop_c":1.0,
"akg_c":-1.0,
"glu__L_c":1.0,
"ile__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ILETA",
"rhea":"RHEA:24801",
"sbo":"SBO:0000176"
}
},
{
"id":"IMPC",
"name":"IMP cyclohydrolase",
"metabolites":{
"fprica_c":1.0,
"h2o_c":-1.0,
"imp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"IMPC",
"rhea":"RHEA:18445",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPDDI",
"name":"Isopentenyl-diphosphate D-isomerase",
"metabolites":{
"__LactoPanGEM__dmpp_c":1.0,
"__LactoPanGEM__ipdp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IPDDI:2",
"sbo":"SBO:0000176"
}
},
{
"id":"LDH_D",
"name":"D-lactate dehydrogenase",
"metabolites":{
"h_c":1.0,
"lac__D_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LDH_D",
"rhea":"RHEA:16369",
"sbo":"SBO:0000176"
}
},
{
"id":"M1PD",
"name":"mannitol-1-phosphate 5-dehydrogenase",
"metabolites":{
"f6p_c":1.0,
"h_c":1.0,
"mnl1p_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20610 or KJMKFHIL_17610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"M1PD",
"rhea":"RHEA:19661",
"sbo":"SBO:0000176"
}
},
{
"id":"MAN6PI",
"name":"mannose-6-phosphate isomerase",
"metabolites":{
"f6p_c":1.0,
"man6p_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MAN6PI",
"sbo":"SBO:0000176"
}
},
{
"id":"MTHFD",
"name":"methylenetetrahydrofolate dehydrogenase (NADP)",
"metabolites":{
"methf_c":1.0,
"mlthf_c":-1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MTHFD",
"rhea":"RHEA:22812",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK1",
"name":"Nucleoside-Diphosphate Kinase (ATP:GDP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gdp_c":-1.0,
"__LactoPanGEM__gtp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK1:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK2",
"name":"Nucleoside-Diphosphate Kinase (ATP:UDP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__udp_c":-1.0,
"__LactoPanGEM__utp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK3",
"name":"Nucleoside-Diphosphate Kinase (ATP:CDP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__cdp_c":-1.0,
"__LactoPanGEM__ctp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK3:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK5",
"name":"Nucleoside-Diphosphate Kinase (ATP:dGDP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dgdp_c":-1.0,
"__LactoPanGEM__dgtp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK5",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK6",
"name":"Nucleoside-Diphosphate Kinase (ATP:dUDP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dudp_c":-1.0,
"__LactoPanGEM__dutp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK6:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NDPK8",
"name":"Nucleoside-Diphosphate Kinase (ATP:dADP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__dadp_c":-1.0,
"__LactoPanGEM__datp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK8:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ORPT_1",
"name":"orotate phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":1.0,
"orot5p_c":-1.0,
"orot_c":1.0,
"ppi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01990 or KJMKFHIL_10220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ORPT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PGAMT",
"name":"phosphoglucosamine mutase",
"metabolites":{
"gam1p_c":-1.0,
"gam6p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PGAMT",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGI_1",
"name":"Glucose-6-Phosphate Isomerase",
"metabolites":{
"__LactoPanGEM__g6p_c":-1.0,
"f6p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGI_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PGM",
"name":"phosphoglycerate mutase",
"metabolites":{
"2pg_c":-1.0,
"3pg_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10980 or KJMKFHIL_19640 or KJMKFHIL_24810 or KJMKFHIL_18350 or KJMKFHIL_06060 or KJMKFHIL_10450",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PGM",
"rhea":"RHEA:15901",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGMT_1",
"name":"Phosphoglucomutase",
"metabolites":{
"__LactoPanGEM__g6p_c":1.0,
"g1p_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03280 or KJMKFHIL_02960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGMT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PHETA1",
"name":"phenylalanine transaminase",
"metabolites":{
"akg_c":-1.0,
"glu__L_c":1.0,
"phe__L_c":-1.0,
"phpyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08350 or KJMKFHIL_06290 or KJMKFHIL_10350 or KJMKFHIL_26420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PHETA1",
"rhea":"RHEA:25152",
"sbo":"SBO:0000176"
}
},
{
"id":"PMANM",
"name":"phosphomannomutase",
"metabolites":{
"man1p_c":-1.0,
"man6p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PMANM",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPAKr_1",
"name":"Propionate kinase",
"metabolites":{
"__LactoPanGEM__adp_c":-1.0,
"__LactoPanGEM__atp_c":1.0,
"ppap_c":-1.0,
"prpnte_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04720 or KJMKFHIL_06380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPAKr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PPM",
"name":"phosphopentomutase",
"metabolites":{
"r1p_c":-1.0,
"r5p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24620",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PPM",
"rhea":"RHEA:18793",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPM2",
"name":"phosphopentomutase (deoxyribose)",
"metabolites":{
"2dr1p_c":-1.0,
"__LactoPanGEM__rbt5p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24620",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPM2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRMICI_1",
"name":"1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase",
"metabolites":{
"__LactoPanGEM__prlp_c":1.0,
"prfp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PRMICI_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRPPS_1",
"name":"Phosphoribosylpyrophosphate synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__prpp_c":1.0,
"amp_c":1.0,
"h_c":1.0,
"r5p_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20640 or KJMKFHIL_19140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PRPPS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PTAr",
"name":"phosphotransacetylase",
"metabolites":{
"accoa_c":-1.0,
"actp_c":1.0,
"coa_c":1.0,
"pi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02830",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PTAr",
"rhea":"RHEA:19521",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP1",
"name":"purine-nucleoside phosphorylase (Adenosine)",
"metabolites":{
"ade_c":1.0,
"adn_c":-1.0,
"pi_c":-1.0,
"r1p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP1",
"rhea":"RHEA:27642",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP2_1",
"name":"purine-nucleoside phosphorylase (Deoxyadenosine)",
"metabolites":{
"2dr1p_c":1.0,
"ade_c":1.0,
"dad_2_c":-1.0,
"pi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP2_1",
"rhea":"RHEA:27742",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP3",
"name":"purine-nucleoside phosphorylase (Guanosine)",
"metabolites":{
"gsn_c":-1.0,
"gua_c":1.0,
"pi_c":-1.0,
"r1p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP3",
"rhea":"RHEA:13233",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP4",
"name":"purine-nucleoside phosphorylase (Deoxyguanosine)",
"metabolites":{
"2dr1p_c":1.0,
"dgsn_c":-1.0,
"gua_c":1.0,
"pi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP4",
"rhea":"RHEA:27738",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP5",
"name":"purine-nucleoside phosphorylase (Inosine)",
"metabolites":{
"hxan_c":1.0,
"ins_c":-1.0,
"pi_c":-1.0,
"r1p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP5",
"rhea":"RHEA:27646",
"sbo":"SBO:0000176"
}
},
{
"id":"PUNP6",
"name":"purine-nucleoside phosphorylase (Deoxyinosine)",
"metabolites":{
"2dr1p_c":1.0,
"din_c":-1.0,
"hxan_c":1.0,
"pi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PUNP6",
"rhea":"RHEA:27750",
"sbo":"SBO:0000176"
}
},
{
"id":"PYNP2r",
"name":"pyrimidine-nucleoside phosphorylase (uracil)",
"metabolites":{
"pi_c":-1.0,
"r1p_c":1.0,
"ura_c":1.0,
"uri_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PYNP2r",
"rhea":"RHEA:24388",
"sbo":"SBO:0000176"
}
},
{
"id":"RBP4E",
"name":"L-ribulose-phosphate 4-epimerase",
"metabolites":{
"ru5p__L_c":-1.0,
"xu5p__D_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12120",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RBP4E",
"rhea":"RHEA:22368",
"sbo":"SBO:0000176"
}
},
{
"id":"RPE",
"name":"ribulose 5-phosphate 3-epimerase",
"metabolites":{
"ru5p__D_c":-1.0,
"xu5p__D_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00690",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RPE",
"rhea":"RHEA:13677",
"sbo":"SBO:0000176"
}
},
{
"id":"RPI",
"name":"ribose-5-phosphate isomerase",
"metabolites":{
"r5p_c":-1.0,
"ru5p__D_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23950 or KJMKFHIL_22780 or KJMKFHIL_15620",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RPI",
"sbo":"SBO:0000176"
}
},
{
"id":"SBTPD",
"name":"sorbitol-6-phosphate dehydrogenase",
"metabolites":{
"f6p_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"sbt6p_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11830",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SBTPD",
"rhea":"RHEA:19837",
"sbo":"SBO:0000176"
}
},
{
"id":"TMDPP",
"name":"thymidine phosphorylase",
"metabolites":{
"2dr1p_c":-1.0,
"pi_c":1.0,
"thym_c":-1.0,
"thymd_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TMDPP",
"rhea":"RHEA:16037",
"sbo":"SBO:0000176"
}
},
{
"id":"TPI",
"name":"triose-phosphate isomerase",
"metabolites":{
"dhap_c":-1.0,
"g3p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TPI",
"sbo":"SBO:0000176"
}
},
{
"id":"HOXPRx",
"name":"tartronate semialdehyde reductase",
"metabolites":{
"2h3opp_c":-1.0,
"glyc__R_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HOXPRx",
"rhea":"RHEA:18845",
"sbo":"SBO:0000176"
}
},
{
"id":"TYRTA",
"name":"tyrosine transaminase",
"metabolites":{
"34hpp_c":1.0,
"akg_c":-1.0,
"glu__L_c":1.0,
"tyr__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08350 or KJMKFHIL_09860 or KJMKFHIL_10350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TYRTA",
"rhea":"RHEA:15093",
"sbo":"SBO:0000176"
}
},
{
"id":"UAG2E",
"name":"UDP-N-acetylglucosamine 2-epimerase",
"metabolites":{
"uacgam_c":-1.0,
"uacmam_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UAG2E",
"rhea":"RHEA:17213",
"sbo":"SBO:0000176"
}
},
{
"id":"UDPG4E",
"name":"UDPglucose 4-epimerase",
"metabolites":{
"udpg_c":-1.0,
"udpgal_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17960 or KJMKFHIL_15460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UDPG4E",
"rhea":"RHEA:22168",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UMPK_1",
"name":"UMP Kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__udp_c":1.0,
"ump_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17870 or KJMKFHIL_00780 or KJMKFHIL_20020 or KJMKFHIL_00320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UMPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"VALTA",
"name":"valine transaminase",
"metabolites":{
"3mob_c":1.0,
"akg_c":-1.0,
"glu__L_c":1.0,
"val__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"VALTA",
"rhea":"RHEA:24813",
"sbo":"SBO:0000176"
}
},
{
"id":"XYLI2",
"name":"xylose isomerase",
"metabolites":{
"fru_c":1.0,
"glc__D_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"XYLI2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACOATA_1",
"name":"Acetyl Coenzyme A Acp Transacylase",
"metabolites":{
"__LactoPanGEM__acacp_c":1.0,
"__LactoPanGEM__acp_c":-1.0,
"accoa_c":-1.0,
"coa_c":1.0,
"h_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACOATA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR180_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C18:0)",
"metabolites":{
"__LactoPanGEM__3hoctaacp_c":1.0,
"__LactoPanGEM__3ooctdacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"EX_h_e",
"name":"Exchange of hydron.",
"metabolites":{
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_h_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_h2o_e",
"name":"Exchange of water.",
"metabolites":{
"h2o_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_h2o_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ca2_e",
"name":"Exchange of calcium(2+).",
"metabolites":{
"ca2_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ca2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cl_e",
"name":"Chloride exchange",
"metabolites":{
"cl_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cl_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_co2_e",
"name":"Exchange of carbon dioxide.",
"metabolites":{
"co2_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_co2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cobalt2_e",
"name":"Exchange of cobalt(2+).",
"metabolites":{
"cobalt2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cobalt2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cu2_e",
"name":"Exchange of copper(2+).",
"metabolites":{
"cu2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cu2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_fe3_e",
"name":"Exchange of iron(3+).",
"metabolites":{
"fe3_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_fe3_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_k_e",
"name":"Exchange of potassium(1+).",
"metabolites":{
"k_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_k_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_mn2_e",
"name":"Exchange of manganese(2+).",
"metabolites":{
"mn2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_mn2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_nh4_e",
"name":"Exchange of ammonium.",
"metabolites":{
"nh4_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_nh4_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_o2_e",
"name":"Exchange of dioxygen.",
"metabolites":{
"o2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_o2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pi_e",
"name":"Exchange of hydrogenphosphate.",
"metabolites":{
"pi_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pi_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_so4_e",
"name":"Exchange of sulfate.",
"metabolites":{
"so4_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_so4_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__na_e_1",
"name":"exchange reaction for Sodium",
"metabolites":{
"__LactoPanGEM__na_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__na_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__mg_e_1",
"name":"Mg exchange",
"metabolites":{
"__LactoPanGEM__mg_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__mg_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__zn_e_1",
"name":"Zinc exchange",
"metabolites":{
"__LactoPanGEM__zn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__zn_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"__LactoPanGEM__ACONIs_1",
"name":"Aconitate isomerase (spontaneous)",
"metabolites":{
"__LactoPanGEM__acon_T_c":-1.0,
"acon_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACONIs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"FALGTHLs",
"name":"formaldehyde glutathione ligase (spontaneous)",
"metabolites":{
"fald_c":-1.0,
"gthrd_c":-1.0,
"hmgth_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FALGTHLs",
"rhea":"RHEA:22488",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__10FTHFGLULL_1",
"name":"10-Formyltetrahydrofolate:L-glutamate ligase (ADP-forming)",
"metabolites":{
"10fthf_c":-1.0,
"__LactoPanGEM__10fthfglu__L_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"glu__L_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__10FTHFGLULL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"23CN2P3",
"name":"R_2__3__cyclic_nucleotide_2__phosphodiesterase__2__3__cyclic_CMP_",
"metabolites":{
"23ccmp_c":-1.0,
"3cmp_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"23CN2P3",
"rhea":"RHEA:27882",
"sbo":"SBO:0000176"
}
},
{
"id":"23CN2P4",
"name":"R_2__3__cyclic_nucleotide_2__phosphodiesterase__2__3___cyclic_GMP_",
"metabolites":{
"23cgmp_c":-1.0,
"3gmp_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"23CN2P4",
"rhea":"RHEA:27858",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__2OXOADOXm_1",
"name":"2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating)",
"metabolites":{
"2oxoadp_c":-1.0,
"__LactoPanGEM__glutcoa_c":1.0,
"co2_c":1.0,
"coa_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06500 or KJMKFHIL_10250 or KJMKFHIL_07340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__2OXOADOXm_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD100_2",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C10:0)",
"metabolites":{
"__LactoPanGEM__3hdecacp_c":-1.0,
"__LactoPanGEM__tdec2eacp_c":1.0,
"h2o_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD100_2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD120",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C12:0)",
"metabolites":{
"__LactoPanGEM__3hddecacp_c":-1.0,
"__LactoPanGEM__tddec2eacp_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD120:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD140",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C14:0)",
"metabolites":{
"__LactoPanGEM__3hmrsacp_c":-1.0,
"__LactoPanGEM__tmrs2eacp_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD140:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD160_1",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C16:0)",
"metabolites":{
"__LactoPanGEM__3hpalmacp_c":-1.0,
"__LactoPanGEM__tpalm2eacp_c":1.0,
"h2o_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD160_1:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD180_2",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C18:0)",
"metabolites":{
"__LactoPanGEM__3hoctaacp_c":-1.0,
"__LactoPanGEM__toctd2eacp_c":1.0,
"h2o_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD180_2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD40",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C4:0)",
"metabolites":{
"__LactoPanGEM__3haacp_c":-1.0,
"__LactoPanGEM__but2eacp_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD40:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD60",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C6:0)",
"metabolites":{
"__LactoPanGEM__3hhexacp_c":-1.0,
"__LactoPanGEM__thex2eacp_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD60:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAD80",
"name":"3-hydroxyacyl-[acyl-carrier-protein] dehydratase (n-C8:0)",
"metabolites":{
"__LactoPanGEM__3hoctacp_c":-1.0,
"__LactoPanGEM__toct2eacp_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAD80:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR121_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C12:1)",
"metabolites":{
"__LactoPanGEM__3hcddec5eacp_c":1.0,
"__LactoPanGEM__3ocddec5eacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR121_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR141_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C14:1)",
"metabolites":{
"__LactoPanGEM__3hcmrs7eacp_c":1.0,
"__LactoPanGEM__3ocmrs7eacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR141_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAR161_1",
"name":"3-oxoacyl-[acyl-carrier-protein] reductase (n-C16:1)",
"metabolites":{
"__LactoPanGEM__3hcpalm9eacp_c":1.0,
"__LactoPanGEM__3ocpalm9eacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAR161_1",
"sbo":"SBO:0000176"
}
},
{
"id":"4ABUTD",
"name":"4-Aminobutyraldehyde:NAD+ oxidoreductase",
"metabolites":{
"4abut_c":1.0,
"4abutn_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"4ABUTD",
"rhea":"RHEA:30803",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4CMLCL_kt_1",
"name":"4-Carboxymuconolactone carboxy-lyase",
"metabolites":{
"5odhf2a_c":1.0,
"__LactoPanGEM__4cml_c":-1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08200 or KJMKFHIL_08210 or KJMKFHIL_09260",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4CMLCL_kt_1",
"sbo":"SBO:0000176"
}
},
{
"id":"4HTHRS",
"name":"4-Hydroxy-L-threonine synthase",
"metabolites":{
"4hthr_c":1.0,
"h2o_c":-1.0,
"phthr_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"4HTHRS",
"rhea":"RHEA:30659",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4MCAT23DOX",
"name":"Catechol 2 3 dioxygenase",
"metabolites":{
"4mcat_c":-1.0,
"__LactoPanGEM__hmccms_c":1.0,
"h_c":1.0,
"o2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4MCAT23DOX",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__5FLURAPRT_1",
"name":"5-fluorouracil phosphoribosyltransferase",
"metabolites":{
"5flura_c":-1.0,
"__LactoPanGEM__5flurimp_c":1.0,
"__LactoPanGEM__prpp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__5FLURAPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"6PGALSZ",
"name":"_6-phospho-beta-galactosidase",
"metabolites":{
"dgal6p_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0,
"lac6p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"6PGALSZ",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__6PHBG_1",
"name":"6-phospho-beta-glucosidase",
"metabolites":{
"2hxmp_c":1.0,
"__LactoPanGEM__g6p_c":1.0,
"__LactoPanGEM__salc6p_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06530 or KJMKFHIL_02260 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__6PHBG_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__6PHBG2_1",
"name":"Salicin 6-phosphate glucohydrolase",
"metabolites":{
"2hxmp_c":1.0,
"M01389_c":1.0,
"__LactoPanGEM__salc6p_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740 or KJMKFHIL_06530 or KJMKFHIL_02260 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__6PHBG2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AALACPTD_1",
"name":"D-alanyl-D-alanine carboxypeptidase",
"metabolites":{
"__LactoPanGEM__ptdegly_c":2.0,
"ala__D_c":2.0,
"h2o_c":-2.0,
"uaagmda_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23160",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AALACPTD_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AATA_1",
"name":"2 aminoadipate transaminase",
"metabolites":{
"2oxoadp_c":1.0,
"__LactoPanGEM__L2aadp_c":-1.0,
"akg_c":-1.0,
"glu__L_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19600",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AATA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AB6PGH_2",
"name":"Arbutin 6-phosphate glucohydrolase",
"metabolites":{
"__LactoPanGEM__g6p_c":1.0,
"arbt6p_c":-1.0,
"h2o_c":-1.0,
"hqn_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740 or KJMKFHIL_06530 or KJMKFHIL_02260 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AB6PGH_2",
"sbo":"SBO:0000176"
}
},
{
"id":"AB6PGH_1",
"name":"Arbutin 6-phosphate glucohydrolase",
"metabolites":{
"M01389_c":1.0,
"arbt6p_c":-1.0,
"h2o_c":-1.0,
"hqn_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740 or KJMKFHIL_06530 or KJMKFHIL_02260 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AB6PGH_1",
"rhea":"RHEA:28510",
"sbo":"SBO:0000176"
}
},
{
"id":"ABUTD",
"name":"Aminobutyraldehyde dehydrogenase",
"metabolites":{
"4abut_c":1.0,
"4abutn_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ABUTD",
"rhea":"RHEA:19105",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT3r",
"name":"acetyl-CoA C-acyltransferase (hexanoyl-CoA) (r)",
"metabolites":{
"3oocoa_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"hxcoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT3r",
"rhea":"RHEA:31203",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT4r",
"name":"acetyl-CoA C-acyltransferase (octanoyl-CoA) (r)",
"metabolites":{
"3odcoa_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"octcoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT4r",
"rhea":"RHEA:31087",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT5r",
"name":"acetyl-CoA C-acyltransferase (decanoyl-CoA) (r)",
"metabolites":{
"3oddcoa_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"dcacoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT5r",
"rhea":"RHEA:31183",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT9",
"name":"acetyl-CoA C-acyltransferase (dodecanoyl-CoA) (r)",
"metabolites":{
"3otdcoa_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"ddcacoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT9",
"rhea":"RHEA:31091",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT12",
"name":"acetyl-CoA C-acyltransferase (tetradecanoyl-CoA) (r)",
"metabolites":{
"3ohdcoa_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"tdcoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT12",
"rhea":"RHEA:18161",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACAMH_1",
"name":"Acylamide aminohydrolase",
"metabolites":{
"bz_c":1.0,
"bzmd_c":-1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACAMH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ACGS",
"name":"N-acetylglutamate synthase",
"metabolites":{
"accoa_c":-1.0,
"acglu_c":1.0,
"coa_c":1.0,
"glu__L_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACGS",
"rhea":"RHEA:24292",
"sbo":"SBO:0000176"
}
},
{
"id":"ACHBS",
"name":"2-aceto-2-hydroxybutanoate synthase",
"metabolites":{
"2ahbut_c":1.0,
"2obut_c":-1.0,
"co2_c":1.0,
"h_c":-1.0,
"pyr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACHBS",
"rhea":"RHEA:27654",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACLDC",
"name":"2-Acetolactate carboxy-lyase_c0",
"metabolites":{
"__LactoPanGEM__alac__S_DUP3_c":-1.0,
"actn__S_c":1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17030 or KJMKFHIL_14990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACLDC",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACPS1_1",
"name":"Acyl-carrier protein synthase",
"metabolites":{
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__apoacp_c":-1.0,
"coa_c":-1.0,
"h_c":2.0,
"pap_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACPS1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ACYP_2",
"name":"acylphosphatase (2)",
"metabolites":{
"ac_c":1.0,
"actp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACYP_2",
"sbo":"SBO:0000176"
}
},
{
"id":"ACYP",
"name":"acylphosphatase",
"metabolites":{
"13dpg_c":-1.0,
"3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACYP",
"sbo":"SBO:0000176"
}
},
{
"id":"ADA",
"name":"Adenosine deaminase",
"metabolites":{
"adn_c":-1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"ins_c":1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06750",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ADA",
"rhea":"RHEA:24408",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ADCLS",
"name":"adenosyl-chloride synthase",
"metabolites":{
"__LactoPanGEM__dcad_c":1.0,
"amet_c":-1.0,
"cl_c":-1.0,
"h_c":1.0,
"met__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADCLS",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ADNCYC_1",
"name":"Adenylate Cyclase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"camp_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03770",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADNCYC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ADEt2",
"name":"adenine transport via proton symport (reversible)",
"metabolites":{
"ade_c":1.0,
"ade_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ADEt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ADPRATr_1",
"name":"ADP:D-ribose-5-phosphate adenylyltransferase",
"metabolites":{
"__LactoPanGEM__adp_c":-1.0,
"adprib_c":1.0,
"h_c":-1.0,
"pi_c":1.0,
"r5p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10340 or KJMKFHIL_07560",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADPRATr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ADPRDP_1",
"name":"ADPribose diphosphatase",
"metabolites":{
"adprib_c":-1.0,
"amp_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"r5p_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10340 or KJMKFHIL_07560",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ADPRDP_1",
"rhea":"RHEA:10412",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ADPT_1",
"name":"Adenine Phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"ade_c":-1.0,
"amp_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00060",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADPT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ADSS_1",
"name":"Adenylosuccinate synthase",
"metabolites":{
"__LactoPanGEM__gdp_c":1.0,
"__LactoPanGEM__gtp_c":-1.0,
"asp__L_c":-1.0,
"dcamp_c":1.0,
"h_c":2.0,
"imp_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05150",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ADSS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"AGDC",
"name":"N-acetylglucosamine-6-phosphate deacetylase",
"metabolites":{
"ac_c":1.0,
"acgam6p_c":-1.0,
"gam6p_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22430 or KJMKFHIL_02540",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AGDC",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT120_2",
"name":"1-tetradecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C12:0)",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__ddcaacp_c":-1.0,
"__LactoPanGEM__pa120_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT120_2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT140",
"name":"1-tetradecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C14:0)",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__pa140_c":1.0,
"__LactoPanGEM__tdeacp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT140:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT141",
"name":"1-tetradec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C14:1)",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__pa141_c":1.0,
"__LactoPanGEM__tdeacp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT141:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT160_1",
"name":"1-hexadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:0)",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__hedacp_c":-1.0,
"__LactoPanGEM__pa160_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT161",
"name":"1-hexadec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C16:1)",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__pa161_c":1.0,
"__LactoPanGEM__palmacp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT161:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT180_2",
"name":"1-octadecanoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C18:0)",
"metabolites":{
"1odecg3p_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__octacp_c":-1.0,
"__LactoPanGEM__pa180_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT180_2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AGPAT181",
"name":"1-octadec-7-enoyl-sn-glycerol 3-phosphate O-acyltransferase (n-C18:1)",
"metabolites":{
"__LactoPanGEM__1odec11eg3p_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__ocdcaacp_c":-1.0,
"__LactoPanGEM__pa181_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AGPAT181:2",
"sbo":"SBO:0000176"
}
},
{
"id":"AHCYSNS",
"name":"S-adenosylhomocysteine nucleosidase",
"metabolites":{
"ade_c":1.0,
"ahcys_c":-1.0,
"h2o_c":-1.0,
"rhcys_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07540",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AHCYSNS",
"rhea":"RHEA:17805",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIHDCDPDAGG3PTr_1",
"name":"anteisoheptadecanoyl-CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase",
"metabolites":{
"__LactoPanGEM__cdpdaihpdecg_c":-1.0,
"__LactoPanGEM__daihedpgp_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIHDCDPDAGG3PTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIHDPCTr_1",
"name":"anteisoheptadecanoyl-phosphatidate cytidylyltransferase",
"metabolites":{
"__LactoPanGEM__cdpdaihpdecg_c":1.0,
"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__paai17_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIHDPCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIHEDDAGK",
"name":"anteisoheptadecanoyl-Diacylglycerol kinase",
"metabolites":{
"__LactoPanGEM__12daihdglyc_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__paai17_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIHEDDAGK:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIHEDLTAS24LGS_1",
"name":"anteisoheptadecanoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
"metabolites":{
"__LactoPanGEM__ai17tcaglc_c":1.0,
"__LactoPanGEM__anteiluc24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIHEDLTAS24LGS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIHEDPGPPH",
"name":"anteisoheptadecanoyl-Phosphatidylglycerophosphate phosphohydrolase",
"metabolites":{
"__LactoPanGEM__daihedpg_c":1.0,
"__LactoPanGEM__daihedpgp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIHEDPGPPH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIPDLTAS_1",
"name":"isohexadecanoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
"metabolites":{
"__LactoPanGEM__i16tca1_c":-1.0,
"__LactoPanGEM__ihxdlpalglcs_c":1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIPDLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIPEDCDPDAGG3PTr_1",
"name":"anteisopentadecanoyl-CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase",
"metabolites":{
"__LactoPanGEM__cdpdaipdecg_c":-1.0,
"__LactoPanGEM__daipedpgp_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIPEDCDPDAGG3PTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIPEDDAGK",
"name":"anteisopentadecanoyl-Diacylglycerol kinase",
"metabolites":{
"__LactoPanGEM__12daipdglyc_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__paai15_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIPEDDAGK:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIPEDPCTr_1",
"name":"anteisopentadecanoyl-phosphatidate cytidylyltransferase",
"metabolites":{
"__LactoPanGEM__cdpdaipdecg_c":1.0,
"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__paai15_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIPEDPCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIPEDPGPPH",
"name":"anteisopentadecanoyl-Phosphatidylglycerophosphate phosphohydrolase",
"metabolites":{
"__LactoPanGEM__daipedpg_c":1.0,
"__LactoPanGEM__daipedpgp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIPEDPGPPH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIRC4_1",
"name":"NCAIR synthetase and NCAIR mutase",
"metabolites":{
"__LactoPanGEM__5aizc_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__air_c":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2co3_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02040 or KJMKFHIL_21500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIRC4_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ALDD2x",
"name":"aldehyde dehydrogenase (acetaldehyde, NAD)",
"metabolites":{
"ac_c":1.0,
"acald_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALDD2x",
"rhea":"RHEA:25294",
"sbo":"SBO:0000176"
}
},
{
"id":"GLYALDDr",
"name":"D-Glyceraldehyde dehydrogenase",
"metabolites":{
"glyald_c":-1.0,
"glyc__R_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLYALDDr",
"rhea":"RHEA:30783",
"sbo":"SBO:0000176"
}
},
{
"id":"AMID",
"name":"R_amidase",
"metabolites":{
"4gudbd_c":-1.0,
"4gudbutn_c":1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AMID",
"rhea":"RHEA:34375",
"sbo":"SBO:0000176"
}
},
{
"id":"AMID5",
"name":"amidase",
"metabolites":{
"aa_c":-1.0,
"acryl_c":1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AMID5",
"rhea":"RHEA:34367",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP1",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_asn__L_c":-1.0,
"asn__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP10_1",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_asp__L_c":-1.0,
"asp__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP10_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP11",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_pro__L_c":-1.0,
"gly_c":1.0,
"h2o_c":-1.0,
"pro__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP11",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP12",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__ala_gln_c":-1.0,
"ala__L_c":1.0,
"gln__L_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP12",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP14_1",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__met_L_ala__L_c":-1.0,
"ala__L_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"met__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP14_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP2",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__ala_L_thr__L_c":-1.0,
"ala__L_c":1.0,
"h2o_c":-1.0,
"thr__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP3",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_gln_c":-1.0,
"gln__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP3",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP4",
"name":"Aminopeptidase",
"metabolites":{
"L_alagly_c":-1.0,
"ala__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP4",
"rhea":"RHEA:36467",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP5_1",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__ala_L_glu__L_c":-1.0,
"ala__L_c":1.0,
"glu__L_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP5_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP6",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__ala_leu_c":-1.0,
"ala__L_c":1.0,
"h2o_c":-1.0,
"leu__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP6",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP7",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__ala_his_c":-1.0,
"ala__L_c":1.0,
"h2o_c":-1.0,
"his__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP7",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP8_1",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_glu__L_c":-1.0,
"glu__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP8_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AMPEP9",
"name":"Aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_met_c":-1.0,
"gly_c":1.0,
"h2o_c":-1.0,
"met__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AMPEP9",
"sbo":"SBO:0000176"
}
},
{
"id":"AMPTASECG",
"name":"alanyl aminopeptidase (cys-gly)",
"metabolites":{
"cgly_c":-1.0,
"cys__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AMPTASECG",
"rhea":"RHEA:28783",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ANPRT_1",
"name":"anthranilate phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"anth_c":-1.0,
"ppi_c":1.0,
"pran_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ANPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"THPAT",
"name":"R_Tetrahydrodipicolinate_acetyltransferase",
"metabolites":{
"acamoxm_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"h2o_c":1.0,
"thdp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THPAT",
"rhea":"RHEA:13085",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__APCPT_1",
"name":"ATP:pantothenate 4'-phosphotransferase",
"metabolites":{
"4ppcys_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"ptcys_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__APCPT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__APNPT_1",
"name":"ATP:pantetheine 4'-phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"pan4p_c":1.0,
"ptth_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__APNPT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ARBabc_1",
"name":"L-arabinose transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"arab__L_c":1.0,
"arab__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11700 or KJMKFHIL_02900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ARBabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ARGSS_1",
"name":"Argininosuccinate synthase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"amp_c":1.0,
"argsuc_c":1.0,
"asp__L_c":-1.0,
"citr__L_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23600",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ARGSS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ARGTRS_1",
"name":"Arginyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__argtrna_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"arg__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ARGTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ASCBPL_1",
"name":"L-ascorbate 6-phosphate lactonase",
"metabolites":{
"3dhgulnp_c":1.0,
"__LactoPanGEM__ascb6p_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12040 or KJMKFHIL_27320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASCBPL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ASNN",
"name":"L-asparaginase",
"metabolites":{
"asn__L_c":-1.0,
"asp__L_c":1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASNN",
"rhea":"RHEA:21016",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ASNS1_1",
"name":"Asparagine synthase (glutamine-hydrolysing)",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"amp_c":1.0,
"asn__L_c":1.0,
"asp__L_c":-1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASNS1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ASNTRS_1",
"name":"Asparaginyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__asntrna_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"asn__L_c":-1.0,
"h_c":-2.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASNTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ASPCT_1",
"name":"aspartate carbamoyltransferase",
"metabolites":{
"asp__L_c":-1.0,
"cbasp_c":1.0,
"cbp_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10160",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASPCT_1",
"rhea":"RHEA:20013",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ASPTRS_1",
"name":"Aspartyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__asptrna_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"asp__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASPTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ASR",
"name":"Arsenate reductase",
"metabolites":{
"__LactoPanGEM__arsna_c":-1.0,
"__LactoPanGEM__aso3_c":1.0,
"gthox_c":1.0,
"gthrd_c":-2.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11720",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASR",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ATPM_1",
"name":"ATP maintenance requirment",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":1.0,
"upper_bound":1.0,
"gene_reaction_rule":"KJMKFHIL_19770 or KJMKFHIL_24880",
"subsystem":"Biomass and maintenance functions",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ATPM_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PMDPHT",
"name":"pyrimidine phosphatase",
"metabolites":{
"4r5au_c":1.0,
"5aprbu_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19630 or KJMKFHIL_17660 or KJMKFHIL_05960 or KJMKFHIL_24330 or KJMKFHIL_07880",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PMDPHT",
"rhea":"RHEA:25197",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BADP",
"name":"beta-Alanyl-N(pai)-methyl-L-histidine hydrolase_c0",
"metabolites":{
"__LactoPanGEM__NPmehis_c":1.0,
"ala_B_c":1.0,
"ans_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13770 or KJMKFHIL_11950",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BADP",
"sbo":"SBO:0000176"
}
},
{
"id":"BGLA",
"name":"Beta-glucosidase",
"metabolites":{
"cellb_c":-1.0,
"glc__D_c":2.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BGLA",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BGALBGLUH",
"name":"beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase",
"metabolites":{
"__LactoPanGEM__gluside_hs_c":1.0,
"__LactoPanGEM__laccer_c":-1.0,
"gal_bD_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740 or KJMKFHIL_06530 or KJMKFHIL_22440 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BGALBGLUH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BGALS",
"name":"beta-galactosidase",
"metabolites":{
"__LactoPanGEM__gluside_hs_c":1.0,
"__LactoPanGEM__laccer_c":-1.0,
"gal_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740 or KJMKFHIL_06530 or KJMKFHIL_22440 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BGALS",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BGLA1_1",
"name":"6-phospho-beta-glucosidase",
"metabolites":{
"6pgg_c":-1.0,
"__LactoPanGEM__g6p_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26740 or KJMKFHIL_06530 or KJMKFHIL_02260 or KJMKFHIL_19420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BGLA1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BGLK_1",
"name":"Beta-glucoside kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__g6p_c":1.0,
"cellb_c":-1.0,
"glc__D_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11970 or KJMKFHIL_19410",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BGLK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BIAMH1_1",
"name":"Biuret amidohydrolase",
"metabolites":{
"__LactoPanGEM__biur_c":-1.0,
"co2_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0,
"urea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BIAMH1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BIAMH2_1",
"name":"biuret amidohydrolase",
"metabolites":{
"__LactoPanGEM__biur_c":-1.0,
"allphn_c":1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BIAMH2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BTNC_1",
"name":"Biotin carboxylase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__btnCCP_c":-1.0,
"__LactoPanGEM__cbtnCCP_c":1.0,
"h2co3_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BTNC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CA2Tr_1",
"name":"\ufeffCalcium-transporting ATPase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"ca2_c":1.0,
"ca2_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21290 or KJMKFHIL_02480 or KJMKFHIL_13180 or KJMKFHIL_15080 or KJMKFHIL_27440 or KJMKFHIL_21020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CA2Tr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CD2abc1_1",
"name":"cadmium transport out via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"cd2_c":-1.0,
"cd2_e":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CD2abc1_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CDPMEK_1",
"name":"4-(cytidine 5-diphospho)-2-C-methyl-D-erythritol kinase",
"metabolites":{
"2p4c2me_c":1.0,
"4c2me_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19070",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CDPMEK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"BGLA:2",
"name":"Beta-glucosidase",
"metabolites":{
"cellb_c":-1.0,
"glc__D_c":2.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19420 or KJMKFHIL_15140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BGLA",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CELYSNADPOX_1",
"name":"N2-(D-1-carboxylethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)",
"metabolites":{
"__LactoPanGEM__lysop_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"lys__L_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02550",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CELYSNADPOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CFAS180_1",
"name":"cyclopropane fatty acid synthase (n18:0)",
"metabolites":{
"__LactoPanGEM__cpocdacp_c":1.0,
"__LactoPanGEM__ocdcaacp_c":-1.0,
"ahcys_c":1.0,
"amet_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12920",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CFAS180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"CHOLID",
"name":"7-?-hydroxysteroid dehydrogenase",
"metabolites":{
"cholate_c":-1.0,
"dhcholn_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CHOLID",
"rhea":"RHEA:19409",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CITMCOAH",
"name":"L-Citramalyl-CoA hydro-lyase, mitochondrial",
"metabolites":{
"__LactoPanGEM__citmcoa__L_c":1.0,
"__LactoPanGEM__itaccoa_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CITMCOAH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CMCHL",
"name":"Citramalyl-CoA hydro-lyase",
"metabolites":{
"__LactoPanGEM__citmcoa_c":1.0,
"__LactoPanGEM__itaccoa_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CMCHL",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CTPFPPTr_1",
"name":"CTP:D-fructose-6-phosphate 1-phosphotransferase",
"metabolites":{
"__LactoPanGEM__cdp_c":1.0,
"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__f26bp_c":1.0,
"f6p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19550 or KJMKFHIL_09000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CTPFPPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CTPS1_1",
"name":"CTP synthase NH3",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__ctp_c":1.0,
"__LactoPanGEM__utp_c":-1.0,
"h_c":2.0,
"nh4_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22390 or KJMKFHIL_17110",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CTPS1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CTPS2_1",
"name":"CTP Synthase (Glutamine)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__ctp_c":1.0,
"__LactoPanGEM__utp_c":-1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22390 or KJMKFHIL_17110",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CTPS2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__Cut1_1",
"name":"Copper export via ATPase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"cu2_c":-1.0,
"cu2_e":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__Cut1_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CYCDES",
"name":"cysteine desulfurase",
"metabolites":{
"__LactoPanGEM__C15811_c":-1.0,
"__LactoPanGEM__C15812_c":1.0,
"ala__L_c":1.0,
"cys__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07930 or KJMKFHIL_10620 or KJMKFHIL_07530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYCDES",
"sbo":"SBO:0000176"
}
},
{
"id":"CYSS_2",
"name":"cysteine synthase",
"metabolites":{
"ac_c":1.0,
"acser_c":-1.0,
"cys__L_c":1.0,
"h2s_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYSS_2",
"rhea":"RHEA:14829",
"sbo":"SBO:0000176"
}
},
{
"id":"CYSTGL",
"name":"R_cystathionine_g_lyase",
"metabolites":{
"2obut_c":1.0,
"cys__L_c":1.0,
"cyst__L_c":-1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27050",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYSTGL",
"rhea":"RHEA:14005",
"sbo":"SBO:0000176"
}
},
{
"id":"CYSTL",
"name":"cystathionine b-lyase",
"metabolites":{
"cyst__L_c":-1.0,
"h2o_c":-1.0,
"hcys__L_c":1.0,
"nh4_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27050 or KJMKFHIL_03830",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYSTL",
"rhea":"RHEA:13965",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CYSTRS_1",
"name":"Cysteinyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__cystrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"cys__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15680",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYSTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"CYTD",
"name":"cytidine deaminase",
"metabolites":{
"cytd_c":-1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0,
"uri_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYTD",
"rhea":"RHEA:16069",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__D5KGK",
"name":"ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__d5kg_c":-1.0,
"__LactoPanGEM__d5kgp_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__D5KGK",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__D5KGPA",
"name":"2-Deoxy-5-keto-D-gluconate 6-phosphate aldolase",
"metabolites":{
"__LactoPanGEM__d5kgp_c":-1.0,
"dhap_c":1.0,
"msa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__D5KGPA",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DADNC_1",
"name":"Diadenylate cyclase",
"metabolites":{
"__LactoPanGEM__atp_c":-2.0,
"__LactoPanGEM__cdiamp_c":1.0,
"ppi_c":2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DADNC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGGT_LBR_1",
"name":"1,2-diacylglycerol 3-glucosyltransferase (LRE specific)",
"metabolites":{
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"__LactoPanGEM__dgdag_LBR_c":1.0,
"__LactoPanGEM__udp_c":2.0,
"h_c":2.0,
"udpg_c":-2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26390 or KJMKFHIL_26380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGGT_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK120_1",
"name":"diacylglycerol kinase (n-C12:0)",
"metabolites":{
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"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa120_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK140_1",
"name":"diacylglycerol kinase (n-C14:0)",
"metabolites":{
"12dgr140_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa140_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK140_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK141_1",
"name":"diacylglycerol kinase (n-C14:1)",
"metabolites":{
"12dgr141_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa141_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK141_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK160_1",
"name":"diacylglycerol kinase (n-C16:0)",
"metabolites":{
"12dgr160_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa160_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK161_1",
"name":"diacylglycerol kinase (n-C16:1)",
"metabolites":{
"12dgr161_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa161_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK161_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK180_1",
"name":"diacylglycerol kinase (n-C18:0)",
"metabolites":{
"12dgr180_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa180_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAGK181_1",
"name":"diacylglycerol kinase (n-C18:1)",
"metabolites":{
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"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pa181_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_07440 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAGK181_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DALAPL_1",
"name":"D-alanine-poly(phosphoribitol) ligase",
"metabolites":{
"__LactoPanGEM__atp_c":-45.0,
"__LactoPanGEM__prenoN_acid_c":-1.0,
"__LactoPanGEM__prl45tcaala_c":1.0,
"ala__D_c":-45.0,
"amp_c":45.0,
"h_c":45.0,
"ppi_c":45.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13610 or KJMKFHIL_13600 or KJMKFHIL_13590 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DALAPL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DALTAL_1",
"name":"D-Alanine lipoteichoic acid ligase",
"metabolites":{
"__LactoPanGEM__LTA_LBR_c":-1.0,
"__LactoPanGEM__LTAala_LBR_c":1.0,
"__LactoPanGEM__adp_c":20.0,
"__LactoPanGEM__atp_c":-20.0,
"ala__D_c":-20.0,
"pi_c":20.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26440 or KJMKFHIL_21540",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DALTAL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ADPDA",
"name":"R_N6_acetyl_LL_2_6_diaminoheptanedioate_amidohydrolase",
"metabolites":{
"26dap_LL_c":1.0,
"26dapime_c":-1.0,
"ac_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05330 or KJMKFHIL_20480",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ADPDA",
"rhea":"RHEA:20405",
"sbo":"SBO:0000176"
}
},
{
"id":"DAPDC",
"name":"diaminopimelate decarboxylase",
"metabolites":{
"26dap__M_c":-1.0,
"co2_c":1.0,
"h_c":-1.0,
"lys__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DAPDC",
"rhea":"RHEA:15101",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN120_1",
"name":"CDP-diacylglycerol synthetase (n-C12:0)",
"metabolites":{
"__LactoPanGEM__cdpdddecg_c":1.0,
"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pa120_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN140_1",
"name":"CDP-diacylglycerol synthetase (n-C14:0)",
"metabolites":{
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"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pa140_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN140_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN141_1",
"name":"CDP-diacylglycerol synthetase (n-C14:1)",
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"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pa141_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN141_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN160_1",
"name":"CDP-diacylglycerol synthetase (n-C16:0)",
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"__LactoPanGEM__pa160_c":-1.0,
"cdpdhdecg_c":1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN161_1",
"name":"CDP-diacylglycerol synthetase (n-C16:1)",
"metabolites":{
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"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pa161_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN161_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN180_1",
"name":"CDP-diacylglycerol synthetase (n-C18:0)",
"metabolites":{
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"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pa180_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DASYN181_1",
"name":"CDP-diacylglycerol synthetase (n-C18:1)",
"metabolites":{
"__LactoPanGEM__cdpdodec11eg_c":1.0,
"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pa181_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DASYN181_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DCTPAMH_1",
"name":"dCTP aminohydrolase (dUMP-forming)",
"metabolites":{
"__LactoPanGEM__dctp_c":-1.0,
"dump_c":1.0,
"h2o_c":-2.0,
"nh4_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DCTPAMH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DCYTD",
"name":"deoxycytidine deaminase",
"metabolites":{
"dcyt_c":-1.0,
"duri_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DCYTD",
"rhea":"RHEA:13433",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DDGLK_1",
"name":"2-dehydro-3-deoxygluconokinase",
"metabolites":{
"2ddg6p_c":1.0,
"2ddglcn_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DDGLK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DEXGLCH",
"name":"Dextrin 6-alpha-D-glucanohydrolase",
"metabolites":{
"__LactoPanGEM__Amylose_c":1.0,
"__LactoPanGEM__Starch_c":-1.0,
"glc__D_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DEXGLCH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DFLOAMH_1",
"name":"5'-deoxy-5-fluorocytidine aminohydrolase",
"metabolites":{
"__LactoPanGEM__dflucy_c":-1.0,
"__LactoPanGEM__doxif_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DFLOAMH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DGDGGH_EPA_EPA_c",
"name":"Digalactosyl-diacylglycerol galactohydrolase",
"metabolites":{
"__LactoPanGEM__dgdg205n3_c":-1.0,
"__LactoPanGEM__mgdg205n3_c":1.0,
"gal_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DGDGGH_EPA_EPA_c",
"sbo":"SBO:0000176"
}
},
{
"id":"DGGH",
"name":"a-galactosidase (melibiose)",
"metabolites":{
"gal_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0,
"melib_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DGGH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DGNSK_1",
"name":"deoxyguanosine kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"dgmp_c":1.0,
"dgsn_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10410",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DGNSK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DHDPRy",
"name":"dihydrodipicolinate reductase (NADPH)",
"metabolites":{
"23dhdp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"thdp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHDPRy",
"sbo":"SBO:0000176"
}
},
{
"id":"DHDPS",
"name":"dihydrodipicolinate synthase",
"metabolites":{
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"aspsa_c":-1.0,
"h2o_c":2.0,
"h_c":1.0,
"pyr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHDPS",
"rhea":"RHEA:14845",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DHFS_1",
"name":"dihydrofolate synthase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"dhf_c":1.0,
"dhpt_c":-1.0,
"glu__L_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DHFS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DHORDi",
"name":"R_dihydoorotic_acid_dehydrogenase__irreversible_",
"metabolites":{
"dhor__S_c":-1.0,
"h2o2_c":1.0,
"o2_c":-1.0,
"orot_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01820",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHORDi",
"sbo":"SBO:0000176"
}
},
{
"id":"DHPPD",
"name":"2,3-dihydroxyphenylpropionate dehydrogenase",
"metabolites":{
"cechddd_c":-1.0,
"dhpppn_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15000 or KJMKFHIL_13160 or KJMKFHIL_09090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHPPD",
"rhea":"RHEA:25062",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DIGALSIDGALH",
"name":"Digalactosylceramide galactohydrolase",
"metabolites":{
"__LactoPanGEM__cereb_c":1.0,
"__LactoPanGEM__digalside_hs_c":-1.0,
"gal_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIGALSIDGALH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DMATT_1",
"name":"Dimethylallyltranstransferase",
"metabolites":{
"__LactoPanGEM__dmpp_c":-1.0,
"__LactoPanGEM__grdp_c":1.0,
"__LactoPanGEM__ipdp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DMATT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DMPPLGDMTr_1",
"name":"dimethylallyl-diphosphate:leachianone-G 2-dimethylallyltransferase",
"metabolites":{
"__LactoPanGEM__dmpp_c":-1.0,
"__LactoPanGEM__leachg_c":-1.0,
"__LactoPanGEM__sophofg_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DMPPLGDMTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DMPPNGDMTr_1",
"name":"dimethylallyl-diphosphate:naringenin 8-dimethylallyltransferase",
"metabolites":{
"__LactoPanGEM__dmpp_c":-1.0,
"__LactoPanGEM__flava_c":1.0,
"__LactoPanGEM__nargn_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06360",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DMPPNGDMTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DMQMT",
"name":"3-Dimethylubiquinonol 3-methyltransferase",
"metabolites":{
"2omhmbl_c":-1.0,
"ahcys_c":1.0,
"amet_c":-1.0,
"h_c":1.0,
"q8h2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DMQMT",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DPCOAK_1",
"name":"Dephospho Coenzyme A Kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"coa_c":1.0,
"dpcoa_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01560",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DPCOAK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DPGM_1",
"name":"Diphosphoglyceromutase",
"metabolites":{
"13dpg_c":-1.0,
"__LactoPanGEM__23dpg_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DPGM_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DPR",
"name":"2-dehydropantoate 2-reductase",
"metabolites":{
"2dhp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"pant__R_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DPR",
"rhea":"RHEA:16233",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DRBK_1",
"name":"Deoxyribokinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__rbt5p_c":1.0,
"drib_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DRBK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DTTPDP",
"name":"DTTP diphosphatase",
"metabolites":{
"__LactoPanGEM__dttp_c":-1.0,
"dtmp_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DTTPDP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DURIK1_1",
"name":"Deoxyuridine Kinase (ATP:Deoxyuridine)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"dump_c":1.0,
"duri_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DURIK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DUTPDP_1",
"name":"DUTP diphosphatase",
"metabolites":{
"__LactoPanGEM__dutp_c":-1.0,
"dump_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18230 or KJMKFHIL_07000 or KJMKFHIL_03710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DUTPDP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"EDA",
"name":"2-dehydro-3-deoxy-phosphogluconate aldolase",
"metabolites":{
"2ddg6p_c":-1.0,
"g3p_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12300 or KJMKFHIL_19460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EDA",
"sbo":"SBO:0000176"
}
},
{
"id":"EPMGH",
"name":"R_Epimelibiose_galactohydrolase",
"metabolites":{
"epm_c":-1.0,
"gal_c":1.0,
"h2o_c":-1.0,
"man_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EPMGH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EPOXQR_1",
"name":"Epoxyqueuosine reductase",
"metabolites":{
"__LactoPanGEM__epquetrna_c":-1.0,
"__LactoPanGEM__quetrna_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__EPOXQR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ETHAAL",
"name":"Ethanolamine ammonia-lyase",
"metabolites":{
"acald_c":1.0,
"etha_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21510",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ETHAAL",
"rhea":"RHEA:15313",
"sbo":"SBO:0000176"
}
},
{
"id":"FACOAE160",
"name":"fatty-acid-CoA thioesterase (hexadecanoate)",
"metabolites":{
"coa_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdca_c":1.0,
"pmtcoa_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FACOAE160",
"rhea":"RHEA:16645",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL140",
"name":"acyl-coenzyme A ligase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0,
"tdcoa_c":1.0,
"ttdca_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL140",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL140_ISO",
"name":"Fatty-acid--CoA ligase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__fa1_c":-1.0,
"__LactoPanGEM__fa1coa_c":1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL140_ISO",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL150_anteiso",
"name":"Fatty acid CoA ligase anteiso C150",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__fa4_c":-1.0,
"__LactoPanGEM__fa4coa_c":1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL150_anteiso",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL150_ISO",
"name":"Fatty acid CoA ligase Iso C150",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__fa3_c":-1.0,
"__LactoPanGEM__fa3coa_c":1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL150_ISO",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL160_ISO",
"name":"Fatty acid CoA ligase Iso C160",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__fa6_c":-1.0,
"__LactoPanGEM__fa6coa_c":1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL160_ISO",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL170_anteiso",
"name":"Fatty acid CoA ligase anteiso C170",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__fa12_c":-1.0,
"__LactoPanGEM__fa12coa_c":1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL170_anteiso",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FACOAL170_ISO",
"name":"FACOAL170(ISO)",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__fa11_c":-1.0,
"__LactoPanGEM__fa11coa_c":1.0,
"amp_c":1.0,
"coa_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FACOAL170_ISO",
"sbo":"SBO:0000176"
}
},
{
"id":"FBA2",
"name":"R_D_Fructose_1_phosphate_D_glyceraldehyde_3_phosphate_lyase",
"metabolites":{
"dhap_c":1.0,
"f1p_c":-1.0,
"glyald_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25460 or KJMKFHIL_17160 or KJMKFHIL_11840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FBA2",
"rhea":"RHEA:30851",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FBP_1",
"name":"Fructose-Bisphosphatase",
"metabolites":{
"__LactoPanGEM__f26bp_c":-1.0,
"f6p_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FBP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"FDH",
"name":"formate dehydrogenase",
"metabolites":{
"co2_c":1.0,
"for_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FDH",
"rhea":"RHEA:15985",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FK_1",
"name":"ATP:6-deoxy-L-galactose 1-phosphotransferase_c0",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"fuc1p__L_c":1.0,
"fuc__L_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FLVR_1",
"name":"flavin reductase",
"metabolites":{
"__LactoPanGEM__ribflvRD_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"ribflv_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16720",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FLVR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FMETDF_1",
"name":"formylmethionine deformylase",
"metabolites":{
"__LactoPanGEM__fmet_c":-1.0,
"for_c":1.0,
"h2o_c":-1.0,
"met__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FMETDF_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FMETTRS_1",
"name":"Methionyl-tRNA formyltransferase",
"metabolites":{
"10fthf_c":-1.0,
"__LactoPanGEM__fmettrna_c":1.0,
"__LactoPanGEM__mettrna_c":-1.0,
"h_c":1.0,
"thf_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FMETTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FMNAT_1",
"name":"ATP:FMN adenylyltransferase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"fad_c":1.0,
"fmn_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FMNAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PKETF",
"name":"Phosphoketolase (fructose-6-phosphate utilizing)",
"metabolites":{
"actp_c":1.0,
"e4p_c":1.0,
"f6p_c":-1.0,
"h2o_c":1.0,
"pi_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04640",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PKETF",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FRTT2_1",
"name":"Farnesyl diphosphate:Isopentenyl diphosphate farnesyl cistransferase",
"metabolites":{
"__LactoPanGEM__frdp_c":-1.0,
"__LactoPanGEM__ipdp_c":-1.0,
"__LactoPanGEM__ttc_ggdp_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FRTT2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FRULYSK_1",
"name":"Fructoselysine Kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"frulys_c":-1.0,
"frulysp_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FRULYSK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G15HPETEOX_1",
"name":"Glutathione: 15-HPETE oxidoreductase",
"metabolites":{
"15HPET_c":-1.0,
"__LactoPanGEM__15HET_c":1.0,
"gthox_c":1.0,
"gthrd_c":-2.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G15HPETEOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"G1PACT",
"name":"glucosamine-1-phosphate N-acetyltransferase",
"metabolites":{
"accoa_c":-1.0,
"acgam1p_c":1.0,
"coa_c":1.0,
"gam1p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19130",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G1PACT",
"rhea":"RHEA:13725",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT120_1",
"name":"Glycerol-3-phosphate acyltransferase (C12:0)",
"metabolites":{
"1ddecg3p_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__ddcaacp_c":-1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT140_1",
"name":"Glycerol-3-phosphate acyltransferase (C14:0)",
"metabolites":{
"__LactoPanGEM__1tdecg3p_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__tdeacp_c":-1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT140_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT141_1",
"name":"Glycerol-3-phosphate acyltransferase (C14:1)",
"metabolites":{
"__LactoPanGEM__1tdec7eg3p_c":1.0,
"__LactoPanGEM__tdeacp_c":-1.0,
"glyc3p_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT141_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT160_1",
"name":"Glycerol-3-phosphate acyltransferase (C16:0)",
"metabolites":{
"__LactoPanGEM__1hdecg3p_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__hedacp_c":-1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT161_1",
"name":"Glycerol-3-phosphate acyltransferase (C16:1)",
"metabolites":{
"__LactoPanGEM__1hdec9eg3p_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__palmacp_c":-1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT161_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT180_1",
"name":"Glycerol-3-phosphate acyltransferase (C18:0)",
"metabolites":{
"1odecg3p_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__octacp_c":-1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PAT181_1",
"name":"Glycerol-3-phosphate acyltransferase (C18:1)",
"metabolites":{
"__LactoPanGEM__1odec11eg3p_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__ocdcaacp_c":-1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00370 or KJMKFHIL_08530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PAT181_1",
"sbo":"SBO:0000176"
}
},
{
"id":"G3PD",
"name":"Glycerol-3-phosphate dehydrogenase (FAD)",
"metabolites":{
"dhap_c":1.0,
"fad_c":-1.0,
"fadh2_c":1.0,
"glyc3p_c":-1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G3PD",
"rhea":"RHEA:31283",
"sbo":"SBO:0000176"
}
},
{
"id":"G3PD5",
"name":"glycerol-3-phosphate dehydrogenase (ubiquinone-8)",
"metabolites":{
"dhap_c":1.0,
"glyc3p_c":-1.0,
"q8_c":-1.0,
"q8h2_c":1.0
},
"lower_bound":0.0,
"upper_bound":0.0,
"gene_reaction_rule":"KJMKFHIL_03300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G3PD5",
"rhea":"RHEA:28751",
"sbo":"SBO:0000176"
}
},
{
"id":"G3PD6",
"name":"glycerol-3-phosphate dehydrogenase (menaquinone-8)",
"metabolites":{
"dhap_c":1.0,
"glyc3p_c":-1.0,
"mql8_c":1.0,
"mqn8_c":-1.0
},
"lower_bound":0.0,
"upper_bound":0.0,
"gene_reaction_rule":"KJMKFHIL_03300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G3PD6",
"rhea":"RHEA:29223",
"sbo":"SBO:0000176"
}
},
{
"id":"G3PD7",
"name":"glycerol-3-phosphate dehydrogenase (demethylmenaquinone-8)",
"metabolites":{
"2dmmq8_c":-1.0,
"2dmmql8_c":1.0,
"dhap_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":0.0,
"gene_reaction_rule":"KJMKFHIL_03300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G3PD7",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G3PO_1",
"name":"Glycerol-3-phosphate oxidase",
"metabolites":{
"dhap_c":-1.0,
"glyc3p_c":1.0,
"h2o2_c":-1.0,
"o2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G3PO_1",
"rhea":"RHEA:18369",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G5HPETEOX_1",
"name":"Glutathione: 5-HPETE oxidoreductase",
"metabolites":{
"C04805_c":1.0,
"__LactoPanGEM__5HPET_c":-1.0,
"gthox_c":1.0,
"gthrd_c":-2.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G5HPETEOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"G5SD",
"name":"glutamate-5-semialdehyde dehydrogenase",
"metabolites":{
"glu5p_c":-1.0,
"glusemald_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10140 or KJMKFHIL_18440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G5SD",
"rhea":"RHEA:19541",
"sbo":"SBO:0000176"
}
},
{
"id":"G6PBDH",
"name":"beta-D-Glucose-6-phosphate_NADP+ 1-oxoreductase",
"metabolites":{
"6pgl_c":1.0,
"M01389_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G6PBDH",
"sbo":"SBO:0000176"
}
},
{
"id":"G6PDA",
"name":"glucosamine-6-phosphate deaminase",
"metabolites":{
"f6p_c":1.0,
"gam6p_c":-1.0,
"h2o_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G6PDA",
"rhea":"RHEA:12172",
"sbo":"SBO:0000176"
}
},
{
"id":"GALCTND",
"name":"galactonate dehydratase",
"metabolites":{
"2dh3dgal_c":1.0,
"galctn__D_c":-1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GALCTND",
"rhea":"RHEA:18649",
"sbo":"SBO:0000176"
}
},
{
"id":"GALIGH",
"name":"R_1_alpha_D_Galactosyl_myo_inositol_galactohydrolase",
"metabolites":{
"1Dgali_c":-1.0,
"gal_c":1.0,
"h2o_c":-1.0,
"inost_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GALIGH",
"sbo":"SBO:0000176"
}
},
{
"id":"GALS4",
"name":"STACHGALACT",
"metabolites":{
"gal_c":1.0,
"h2o_c":-1.0,
"raffin_c":1.0,
"stys_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GALS4",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GALT_1",
"name":"Galactose 1 phosphate uridylyltransferase",
"metabolites":{
"__LactoPanGEM__gal1p_c":-1.0,
"__LactoPanGEM__utp_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0,
"udpgal_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15450",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GALT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GALUi",
"name":"UTP-glucose-1-phosphate uridylyltransferase (irreversible)",
"metabolites":{
"__LactoPanGEM__utp_c":-1.0,
"g1p_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0,
"udpg_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GALUi",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GALURK_1",
"name":"ATP:D-galacturonate 1-phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__galur1p_c":1.0,
"galur_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GALURK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GCALDD",
"name":"Glycolaldehyde dehydrogenase",
"metabolites":{
"gcald_c":-1.0,
"glyclt_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21190",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GCALDD",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GCCb_1",
"name":"S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming)",
"metabolites":{
"__LactoPanGEM__alpro_c":-1.0,
"__LactoPanGEM__dhlpro_c":1.0,
"mlthf_c":1.0,
"nh4_c":1.0,
"thf_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07350 or KJMKFHIL_10700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GCCb_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GF6PTA",
"name":"glutamine-fructose-6-phosphate transaminase",
"metabolites":{
"f6p_c":-1.0,
"gam6p_c":1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GF6PTA",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GGLGH",
"name":"Galactosylglycerol galactohydrolase",
"metabolites":{
"__LactoPanGEM__ggl_c":-1.0,
"gal_c":1.0,
"glyc_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GGLGH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLC3_1",
"name":"1,4-alpha-glucan-branching enzyme",
"metabolites":{
"__LactoPanGEM__glycogen_c":-1.0,
"__LactoPanGEM__glycogenb_c":1.0,
"g1p_c":1.0,
"pi_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLC3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLCabc_1",
"name":"D-glucose transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"glc__D_c":1.0,
"glc__D_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02950",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLCabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLCNHL",
"name":"D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)",
"metabolites":{
"2ddglcn_c":1.0,
"glcn_c":-1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLCNHL",
"rhea":"RHEA:21612",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLCS1_1",
"name":"glycogen synthase (ADPGlc)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__glycogen_c":1.0,
"__LactoPanGEM__glycogenb_c":-1.0,
"adpglc_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLCS1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLGC_1",
"name":"glucose-1-phosphate adenylyltransferase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"adpglc_c":1.0,
"g1p_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLGC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLK1_3_1",
"name":"ATP:beta-D-glucose 6-phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__g6p_c":1.0,
"glc__D_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01070",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLK1_3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLNS_1",
"name":"glutamine synthetase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"gln__L_c":1.0,
"glu__L_c":-1.0,
"h_c":1.0,
"nh4_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17100 or KJMKFHIL_01000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLNS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLNSP1_1",
"name":"glutamine synthetase (uaaAgld)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__uaaAgla_c":-1.0,
"__LactoPanGEM__uaaAgtla_c":1.0,
"h_c":1.0,
"nh4_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17100 or KJMKFHIL_01000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLNSP1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLNSP3_1",
"name":"glutamine synthetase (uaagmda)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__uaagtmda_c":1.0,
"h_c":1.0,
"nh4_c":-1.0,
"pi_c":1.0,
"uaagmda_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17100 or KJMKFHIL_01000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLNSP3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLTAL_1",
"name":"Glucose lipoteichoic acid ligase",
"metabolites":{
"__LactoPanGEM__LTA_LBR_c":-1.0,
"__LactoPanGEM__LTAglc_LBR_c":1.0,
"__LactoPanGEM__udp_c":20.0,
"h_c":20.0,
"udpg_c":-20.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26440 or KJMKFHIL_21540",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLTAL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLU5K_1",
"name":"glutamate 5-kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"glu5p_c":1.0,
"glu__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18450",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLU5K_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLUATPPTr_1",
"name":"ATP:L-glutamate 1-phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__glu1p_c":1.0,
"glu__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03100",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLUATPPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLUCYS_1",
"name":"Gamma-glutamylcysteine synthetase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"cys__L_c":-1.0,
"glu__L_c":-1.0,
"glucys_c":1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLUCYS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLUPRT_1",
"name":"Glutamine phosphoribosyldiphosphate amidotransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2o_c":-1.0,
"ppi_c":1.0,
"pram_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLUPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLUTRS_1",
"name":"Glutamyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__glutrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"glu__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15640",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLUTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYC3PDH_1",
"name":"Glycerol-3-phosphate dehydrogenase (ubiquinone-8)",
"metabolites":{
"__LactoPanGEM__q_c":-1.0,
"__LactoPanGEM__qh2_c":1.0,
"dhap_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYC3PDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GLYCLTDy",
"name":"Glycolate dehydrogenase (NADP)",
"metabolites":{
"glx_c":-1.0,
"glyclt_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22920",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLYCLTDy",
"rhea":"RHEA:10992",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYCYSAP",
"name":"Gly-Cys aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_cys_c":-1.0,
"cys__L_c":1.0,
"gly_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYCYSAP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYK_1",
"name":"Glycerol Kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"glyc3p_c":1.0,
"glyc_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15490 or KJMKFHIL_19530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYLEUAP",
"name":"Gly-Leu aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_leu_c":-1.0,
"gly_c":1.0,
"h2o_c":-1.0,
"leu__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYLEUAP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYPHEAP",
"name":"Gly-Phe aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_phe_c":-1.0,
"gly_c":1.0,
"h2o_c":-1.0,
"phe__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYPHEAP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYTYRAP",
"name":"Gly-Try aminopeptidase",
"metabolites":{
"__LactoPanGEM__gly_tyr_c":-1.0,
"gly_c":1.0,
"h2o_c":-1.0,
"tyr__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYTYRAP",
"sbo":"SBO:0000176"
}
},
{
"id":"GMHEPPA",
"name":"D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase",
"metabolites":{
"gmhep17bp_c":-1.0,
"gmhep1p_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GMHEPPA",
"rhea":"RHEA:28518",
"sbo":"SBO:0000176"
}
},
{
"id":"GMPR",
"name":"GMP reductase",
"metabolites":{
"gmp_c":-1.0,
"h_c":-2.0,
"imp_c":1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03670",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GMPR",
"rhea":"RHEA:17185",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GMPS2_1",
"name":"GMP synthase (glutamine-hydrolysing)",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"amp_c":1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"gmp_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"ppi_c":1.0,
"xmp_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GMPS2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GND",
"name":"phosphogluconate dehydrogenase",
"metabolites":{
"6pgc_c":-1.0,
"co2_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0,
"ru5p__D_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GND",
"rhea":"RHEA:10116",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GND2_1",
"name":"Phosphogluconate dehydrogenase",
"metabolites":{
"6pgc_c":-1.0,
"co2_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"ru5p__D_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01280 or KJMKFHIL_23220 or KJMKFHIL_11990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GND2_1",
"rhea":"RHEA:33023",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GNK_1",
"name":"gluconokinase",
"metabolites":{
"6pgc_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"glcn_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GNK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GNMT",
"name":"glycine N-methyltransferase",
"metabolites":{
"ahcys_c":1.0,
"amet_c":-1.0,
"gly_c":-1.0,
"h_c":1.0,
"sarcs_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GNMT",
"sbo":"SBO:0000176"
}
},
{
"id":"GPDDA1",
"name":"Glycerophosphodiester phosphodiesterase (Glycerophosphocholine)",
"metabolites":{
"chol_c":1.0,
"g3pc_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13780 or KJMKFHIL_01830 or KJMKFHIL_11730 or KJMKFHIL_11740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GPDDA1",
"rhea":"RHEA:16061",
"sbo":"SBO:0000176"
}
},
{
"id":"GPDDA2",
"name":"Glycerophosphodiester phosphodiesterase (Glycerophosphoethanolamine)",
"metabolites":{
"etha_c":1.0,
"g3pe_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13780 or KJMKFHIL_01830 or KJMKFHIL_11730 or KJMKFHIL_11740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GPDDA2",
"sbo":"SBO:0000176"
}
},
{
"id":"GPDDA4",
"name":"Glycerophosphodiester phosphodiesterase (Glycerophosphoglycerol)",
"metabolites":{
"g3pg_c":-1.0,
"glyc3p_c":1.0,
"glyc_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13780 or KJMKFHIL_01830 or KJMKFHIL_11730 or KJMKFHIL_11740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GPDDA4",
"rhea":"RHEA:29907",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GRTT_1",
"name":"Geranyltranstransferase",
"metabolites":{
"__LactoPanGEM__frdp_c":1.0,
"__LactoPanGEM__grdp_c":-1.0,
"__LactoPanGEM__ipdp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GRTT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GTHPi",
"name":"glutathione peridoxase",
"metabolites":{
"gthox_c":1.0,
"gthrd_c":-2.0,
"h2o2_c":-1.0,
"h2o_c":2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GTHPi",
"rhea":"RHEA:16833",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GTPCII2_1",
"name":"GTP cyclohydrolase II (25drapp)",
"metabolites":{
"25drapp_c":1.0,
"__LactoPanGEM__gtp_c":-1.0,
"for_c":1.0,
"h2o_c":-3.0,
"h_c":2.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GTPCII2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GTPDPDP_1",
"name":"Guanosine-5'-triphosphate,3'-diphosphate diphosphatase",
"metabolites":{
"__LactoPanGEM__gdptp_c":-1.0,
"__LactoPanGEM__ppgpp_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18800",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GTPDPDP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GTPDPK_1",
"name":"GTP diphosphokinase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gdptp_c":1.0,
"__LactoPanGEM__gtp_c":-1.0,
"amp_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09400 or KJMKFHIL_03760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GTPDPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GUAD_1",
"name":"guanine deaminase",
"metabolites":{
"gua_c":-1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0,
"xan_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11120",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GUAD_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GUAPRT_1",
"name":"Guanine Phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"gmp_c":1.0,
"gua_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GUAPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HCHAMH",
"name":"2-Hydroxy-cyclohexan-1-one amidohydrolase",
"metabolites":{
"6ax_c":1.0,
"__LactoPanGEM__epcap_c":-1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HCHAMH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HEDESAT_1",
"name":"",
"metabolites":{
"__LactoPanGEM__hedacp_c":-1.0,
"__LactoPanGEM__palmacp_c":1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HEDESAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HETZK",
"name":"hydroxyethylthiazole kinase",
"metabolites":{
"4mhetz_c":-1.0,
"4mpetz_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22680",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HETZK",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLK1_3_1:2",
"name":"ATP:beta-D-glucose 6-phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__g6p_c":1.0,
"glc__D_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01070",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLK1_3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HEXTT_1",
"name":"trans-hexaprenyltranstransferase",
"metabolites":{
"__LactoPanGEM__hepdp_c":1.0,
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"__LactoPanGEM__ipdp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15810 or KJMKFHIL_06370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HEXTT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"HISTP_1",
"name":"histidinol-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"hisp_c":-1.0,
"histd_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10400 or KJMKFHIL_08290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HISTP_1",
"rhea":"RHEA:14465",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HISTRS_1",
"name":"Histidyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__histrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"his__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09510",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HISTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"HKNDDH",
"name":"2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase",
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"h_c":1.0,
"hkndd_c":-1.0,
"op4en_c":1.0,
"succ_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13070",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HKNDDH",
"sbo":"SBO:0000176"
}
},
{
"id":"HMGCOAR",
"name":"Hydroxymethylglutaryl CoA reductase (ir)",
"metabolites":{
"coa_c":-1.0,
"h_c":2.0,
"hmgcoa_c":1.0,
"mev__R_c":-1.0,
"nadp_c":-2.0,
"nadph_c":2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HMGCOAR",
"rhea":"RHEA:15989",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HMPK1_1",
"name":"hydroxymethylpyrimidine kinase (ATP)",
"metabolites":{
"4ahmmp_c":-1.0,
"4ampm_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15180 or KJMKFHIL_22700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMPK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HMR_3859_1",
"name":"(R)-Lactate:ferricytochrome-c 2-oxidoreductase",
"metabolites":{
"__LactoPanGEM__ficytC_c":-2.0,
"__LactoPanGEM__focytC_c":2.0,
"h_c":2.0,
"lac__D_c":-1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22920 or KJMKFHIL_06280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMR_3859_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HMR_8643_1",
"name":"Carboxylesterase",
"metabolites":{
"bz_c":1.0,
"coke_c":-1.0,
"egme_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMR_8643_1",
"rhea":"RHEA:27506",
"sbo":"SBO:0000176"
}
},
{
"id":"HPYRRy",
"name":"Hydroxypyruvate reductase (NADPH)",
"metabolites":{
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"h_c":-1.0,
"hpyr_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22920 or KJMKFHIL_09970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HPYRRy",
"rhea":"RHEA:18657",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HSK_1",
"name":"homoserine kinase",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"hom__L_c":-1.0,
"phom_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09800 or KJMKFHIL_06210",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HSK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HXPRT_1",
"name":"Hypoxanthine phosphoribosyltransferase (Hypoxanthine)",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"hxan_c":-1.0,
"imp_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HXPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ICHORT",
"name":"isochorismatase",
"metabolites":{
"23ddhb_c":1.0,
"h2o_c":-1.0,
"ichor_c":-1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ICHORT",
"sbo":"SBO:0000176"
}
},
{
"id":"IGPDH",
"name":"imidazoleglycerol-phosphate dehydratase",
"metabolites":{
"eig3p_c":-1.0,
"h2o_c":1.0,
"imacp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"IGPDH",
"rhea":"RHEA:11040",
"sbo":"SBO:0000176"
}
},
{
"id":"IGPS",
"name":"indole-3-glycerol-phosphate synthase",
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"3ig3p_c":1.0,
"co2_c":1.0,
"h2o_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"IGPS",
"rhea":"RHEA:23476",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHDCDPDAGG3PTr_1",
"name":"isoheptadecanoyl-CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase",
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"__LactoPanGEM__dihedpgp_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHDCDPDAGG3PTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHDPCTr_1",
"name":"isoheptadecanoyl-phosphatidate cytidylyltransferase",
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"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__pai17_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHDPCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHEDDAGK",
"name":"isoheptadecanoyl-Diacylglycerol kinase",
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"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
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},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_14290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHEDDAGK:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHEDLTASLGS_1",
"name":"isoheptadecanoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
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"__LactoPanGEM__isoheluc24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHEDLTASLGS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHEDPCTr_1",
"name":"isohexadecanoyl-phosphatidate cytidylyltransferase",
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"__LactoPanGEM__pai16_c":-1.0,
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"gene_reaction_rule":"KJMKFHIL_00290",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHEDPCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHEDPGPPH",
"name":"isoheptadecanoyl-Phosphatidylglycerophosphate phosphohydrolase",
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"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHEDPGPPH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHXDCDPDAGG3PTr_1",
"name":"isohexadecanoyl-CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase",
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"__LactoPanGEM__dihxdpgp_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHXDCDPDAGG3PTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHXDDAGK",
"name":"isohexadecanoyl-Diacylglycerol kinase",
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"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_14290",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__IHXDDAGK:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHXDPGPPH",
"name":"isohexadecanoyl-Phosphatidylglycerophosphate phosphohydrolase",
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},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHXDPGPPH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ILETRS_1",
"name":"Isoleucyl-tRNA synthetase",
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"__LactoPanGEM__trna_c":-1.0,
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"ppi_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_07620",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ILETRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"IMACTD",
"name":"Imidazole acetaldeyde dehydrogenase",
"metabolites":{
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"h_c":2.0,
"im4ac_c":1.0,
"im4act_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"IMACTD",
"rhea":"RHEA:31059",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPDLTAS_1",
"name":"anteisopentadecanoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
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"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
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"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__IPDLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPEDCDPDAGG3PTr_1",
"name":"isopentadecanoyl-CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase",
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"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__IPEDCDPDAGG3PTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPEDDAGK",
"name":"isopentadecanoyl-Diacylglycerol kinase",
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},
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"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_14290",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__IPEDDAGK:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPEDPCTr_1",
"name":"isopentadecanoyl-phosphatidate cytidylyltransferase",
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"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__IPEDPCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPEDPGPPH",
"name":"isopentadecanoyl-Phosphatidylglycerophosphate phosphohydrolase",
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"h2o_c":-1.0,
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},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__IPEDPGPPH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITCY_1",
"name":"ITPcytidine 5-phosphotransferase",
"metabolites":{
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"__LactoPanGEM__itp_c":-1.0,
"cmp_c":1.0,
"cytd_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ITCY_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITDLTAS_1",
"name":"isopentadecanoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
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"__LactoPanGEM__isopensu24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__ITDLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITEDCDPDAGG3PTr_1",
"name":"isotetradecanoyl-CDPdiacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase",
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"__LactoPanGEM__ditedpgp_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__ITEDCDPDAGG3PTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITEDDAGK",
"name":"isotetradecanoyl-Diacylglycerol kinase",
"metabolites":{
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"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pai14_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24770 or KJMKFHIL_14290",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__ITEDDAGK:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITEDPCTr_1",
"name":"isotetradecanoyl-phosphatidate cytidylyltransferase",
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"__LactoPanGEM__ctp_c":-1.0,
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"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00290",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__ITEDPCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITEDPGPPH",
"name":"isotetradecanoyl-Phosphatidylglycerophosphate phosphohydrolase",
"metabolites":{
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"__LactoPanGEM__ditedpgp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ITEDPGPPH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITLTAS_1",
"name":"isotetradecanoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
"metabolites":{
"__LactoPanGEM__isoteluc24_c":1.0,
"__LactoPanGEM__isotensu24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ITLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITPFPPTr_1",
"name":"ITP:D-fructose-6-phosphate 1-phosphotransferase",
"metabolites":{
"__LactoPanGEM__f26bp_c":1.0,
"__LactoPanGEM__idp_c":1.0,
"__LactoPanGEM__itp_c":-1.0,
"f6p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19550 or KJMKFHIL_09000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ITPFPPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__kaasIII_1",
"name":"beta-ketoacyl-ACP synthase III",
"metabolites":{
"__LactoPanGEM__actacp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"accoa_c":-1.0,
"co2_c":1.0,
"coa_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__kaasIII_1",
"sbo":"SBO:0000176"
}
},
{
"id":"KG6PDC",
"name":"3-keto-L-gulonate 6-phosphate decarboxylase",
"metabolites":{
"3dhgulnp_c":-1.0,
"co2_c":1.0,
"h_c":-1.0,
"xu5p__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"KG6PDC",
"rhea":"RHEA:14353",
"sbo":"SBO:0000176"
}
},
{
"id":"L_LACD2",
"name":"L-Lactate dehydrogenase (ubiquinone)",
"metabolites":{
"lac__L_c":-1.0,
"pyr_c":1.0,
"q8_c":-1.0,
"q8h2_c":1.0
},
"lower_bound":0.0,
"upper_bound":0.0,
"gene_reaction_rule":"KJMKFHIL_18910 or KJMKFHIL_23250 or KJMKFHIL_18380 or KJMKFHIL_22170 or KJMKFHIL_07330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"L_LACD2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__L_LACD_1",
"name":"(S)-Lactate:ferricytochrome-c 2-oxidoreductase",
"metabolites":{
"__LactoPanGEM__ficytC_c":-2.0,
"__LactoPanGEM__focytC_c":2.0,
"h_c":2.0,
"lac__L_c":-1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":0.0,
"gene_reaction_rule":"KJMKFHIL_18910 or KJMKFHIL_23250 or KJMKFHIL_18380 or KJMKFHIL_22170 or KJMKFHIL_07330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__L_LACD_1",
"sbo":"SBO:0000176"
}
},
{
"id":"LALDO3",
"name":"L-Lactaldehyde:NADP+ 1-oxidoreductase",
"metabolites":{
"h_c":-1.0,
"lald__L_c":1.0,
"mthgxl_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23200 or KJMKFHIL_25800",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LALDO3",
"rhea":"RHEA:21748",
"sbo":"SBO:0000176"
}
},
{
"id":"LCADi",
"name":"lactaldehyde dehydrogenase",
"metabolites":{
"h2o_c":-1.0,
"h_c":2.0,
"lac__L_c":1.0,
"lald__L_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21190",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LCADi",
"rhea":"RHEA:14277",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LEUTRS_1",
"name":"Leucyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__leutrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"leu__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LEUTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPGS_LBR_1",
"name":"lysylphosphatidyl-glycerol synthetase",
"metabolites":{
"__LactoPanGEM__lyspg_LBR_c":1.0,
"__LactoPanGEM__lystrna_c":-1.0,
"__LactoPanGEM__pg_LBR_c":-1.0,
"__LactoPanGEM__trna_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPGS_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A120pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C12:0)",
"metabolites":{
"1ddecg3p_c":-1.0,
"ddca_c":1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A120pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A140pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C14:0)",
"metabolites":{
"__LactoPanGEM__1tdecg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A140pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A141pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C14:1)",
"metabolites":{
"__LactoPanGEM__1tdec7eg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A141pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A160pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C16:0)",
"metabolites":{
"__LactoPanGEM__1hdecg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A160pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A161pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C16:1)",
"metabolites":{
"__LactoPanGEM__1hdec9eg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A161pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A180pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C18:0)",
"metabolites":{
"1odecg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A180pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1A181pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphotidate, n-C18:1)",
"metabolites":{
"__LactoPanGEM__1odec11eg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1A181pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1E120pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C12:0)",
"metabolites":{
"1agpe120_c":-1.0,
"ddca_c":1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1E120pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1E140pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C14:0)",
"metabolites":{
"1agpe140_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1E140pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1E141pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C14:1)",
"metabolites":{
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"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1E141pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1E160pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C16:0)",
"metabolites":{
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"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1E160pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1E161pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C16:1)",
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"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1E161pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1E181pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C18:1)",
"metabolites":{
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"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1E181pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G120pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C12:0)",
"metabolites":{
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"ddca_c":1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G120pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G140pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C14:0)",
"metabolites":{
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"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G140pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G141pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C14:1)",
"metabolites":{
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"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G141pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G160pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C16:0)",
"metabolites":{
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"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G160pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G161pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C16:1)",
"metabolites":{
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"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdcea_c":1.0
},
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"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G161pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G180pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C18:0)",
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"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G180pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL1G181pp",
"name":"Lysophospholipase L1 (2-acylglycerophosphoglycerol, n-C18:1)",
"metabolites":{
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"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL1G181pp",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A120",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C12:0)",
"metabolites":{
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"ddca_c":1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A120",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A140",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C14:0)",
"metabolites":{
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"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"ttdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A140",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A141",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C14:1)",
"metabolites":{
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"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"ttdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A141",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A160",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C16:0)",
"metabolites":{
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"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"hdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A160",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A161",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C16:1)",
"metabolites":{
"__LactoPanGEM__2hdec9eg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"hdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A161",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A180",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C18:0)",
"metabolites":{
"__LactoPanGEM__2odecg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"ocdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A180",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2A181",
"name":"Lysophospholipase L2 (2-acylglycerophosphotidate, n-C18:1)",
"metabolites":{
"__LactoPanGEM__2odec11eg3p_c":-1.0,
"glyc3p_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"ocdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2A181",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2E120",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C12:0)",
"metabolites":{
"__LactoPanGEM__2agpe120_c":-1.0,
"ddca_c":1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2E120",
"sbo":"SBO:0000176"
}
},
{
"id":"LPLIPAL2E140",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C14:0)",
"metabolites":{
"2agpe140_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LPLIPAL2E140",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2E141",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C14:1)",
"metabolites":{
"__LactoPanGEM__2agpe141_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2E141",
"sbo":"SBO:0000176"
}
},
{
"id":"LPLIPAL2E160",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C16:0)",
"metabolites":{
"2agpe160_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LPLIPAL2E160",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2E161",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C16:1)",
"metabolites":{
"__LactoPanGEM__2agpe161_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2E161",
"sbo":"SBO:0000176"
}
},
{
"id":"LPLIPAL2E180",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C18:0)",
"metabolites":{
"2agpe180_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LPLIPAL2E180",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2E181",
"name":"Lysophospholipase L2 (2-acylglycerophosphoethanolamine, n-C18:1)",
"metabolites":{
"__LactoPanGEM__2agpe181_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2E181",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G120",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C12:0)",
"metabolites":{
"__LactoPanGEM__2agpg120_c":-1.0,
"ddca_c":1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G120",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G140",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C14:0)",
"metabolites":{
"__LactoPanGEM__2agpg140_c":-1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G140",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G141",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C14:1)",
"metabolites":{
"__LactoPanGEM__2agpg141_c":-1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ttdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G141",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G160",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C16:0)",
"metabolites":{
"__LactoPanGEM__2agpg160_c":-1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G160",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G161",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C16:1)",
"metabolites":{
"__LactoPanGEM__2agpg161_c":-1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"hdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G161",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G180",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C18:0)",
"metabolites":{
"__LactoPanGEM__2agpg180_c":-1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G180",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLIPAL2G181",
"name":"Lysophospholipase L2 (2-acylglycerophosphoglycerol, n-C18:1)",
"metabolites":{
"__LactoPanGEM__2agpg181_c":-1.0,
"g3pg_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdcea_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLIPAL2G181",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LPLL1",
"name":"Lysophospholipase L1 (2-acylglycerophosphoethanolamine, n-C18:0)",
"metabolites":{
"__LactoPanGEM__1agpe180_c":-1.0,
"g3pe_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ocdca_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LPLL1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LTAS_LBR",
"name":"Lipoteichoic acid synthase (LRE specific)",
"metabolites":{
"__LactoPanGEM__LTA_LBR_c":1.0,
"__LactoPanGEM__dag_LBR_c":20.0,
"__LactoPanGEM__dgdag_LBR_c":-20.0,
"__LactoPanGEM__pg_LBR_c":-20.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26440 or KJMKFHIL_21540",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LTAS_LBR",
"sbo":"SBO:0000176"
}
},
{
"id":"LYSt2r",
"name":"L-lysine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"lys__L_c":1.0,
"lys__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17050",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LYSt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__LYSTRS_1",
"name":"Lysyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__lystrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"lys__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LYSTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MAL6PG_1",
"name":"Maltose 6 phosphate glucosidase",
"metabolites":{
"__LactoPanGEM__g6p_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0,
"malt6p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MAL6PG_1",
"sbo":"SBO:0000176"
}
},
{
"id":"MALLAC",
"name":"malolactic enzyme",
"metabolites":{
"co2_c":1.0,
"h_c":-1.0,
"lac__L_c":1.0,
"mal__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13100",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MALLAC",
"rhea":"RHEA:46276",
"sbo":"SBO:0000176"
}
},
{
"id":"MALT",
"name":"alpha-glucosidase",
"metabolites":{
"glc__D_c":2.0,
"h2o_c":-1.0,
"malt_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_17410 or KJMKFHIL_19390 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MALT",
"sbo":"SBO:0000176"
}
},
{
"id":"ME1",
"name":"malic enzyme (NAD)",
"metabolites":{
"co2_c":1.0,
"mal__L_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13100",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ME1",
"rhea":"RHEA:12653",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MELTGH",
"name":"Melibiitol galactohydrolase",
"metabolites":{
"__LactoPanGEM__melt_c":-1.0,
"gal_c":1.0,
"h2o_c":-1.0,
"sbt__D_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MELTGH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__METAT_1",
"name":"Methionine Adenosyltransferase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"amet_c":1.0,
"h2o_c":-1.0,
"met__L_c":-1.0,
"pi_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04480",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__METSOXR2",
"name":"L-methionine-R-sulfoxide reductase",
"metabolites":{
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0,
"met__L_c":1.0,
"metsox_R__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07950",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METSOXR2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__METTRS_1",
"name":"Methionyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__mettrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"met__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18950",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"MHPGLUT2",
"name":"5 methyltetrahydropteroyltriglutamate homocysteine S methyltransferase",
"metabolites":{
"ahcys_c":-1.0,
"amet_c":1.0,
"h_c":-1.0,
"hpglu_c":1.0,
"mhpglu_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MHPGLUT2",
"sbo":"SBO:0000176"
}
},
{
"id":"MI1PP",
"name":"myo-inositol 1-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"inost_c":1.0,
"mi1p__D_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MI1PP",
"rhea":"RHEA:27670",
"sbo":"SBO:0000176"
}
},
{
"id":"MI3PP",
"name":"myo-inositol 3-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"inost_c":1.0,
"mi3p__D_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MI3PP",
"rhea":"RHEA:30739",
"sbo":"SBO:0000176"
}
},
{
"id":"MI4PP",
"name":"myo-inositol 4-phosphatase",
"metabolites":{
"h2o_c":-1.0,
"inost_c":1.0,
"mi4p__D_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MI4PP",
"rhea":"RHEA:30735",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTAS_1",
"name":"myristoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
"metabolites":{
"__LactoPanGEM__myrisluc24_c":1.0,
"__LactoPanGEM__myrisnsu24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTG1",
"name":"Maltodextrin Glucosidase (Maltotriose)",
"metabolites":{
"__LactoPanGEM__malttr_c":-1.0,
"glc__D_c":1.0,
"h2o_c":-1.0,
"malt_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTG1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTG2",
"name":"Maltodextrin glucosidase (maltotetraose)",
"metabolites":{
"__LactoPanGEM__malttr_c":1.0,
"__LactoPanGEM__maltttr_c":-1.0,
"glc__D_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTG2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTG3",
"name":"Maltodextrin glucosidase (maltopentaose)",
"metabolites":{
"__LactoPanGEM__maltpt_c":-1.0,
"__LactoPanGEM__maltttr_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTG3",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTG4",
"name":"Maltodextrin glucosidase (maltohexaose)",
"metabolites":{
"__LactoPanGEM__malthx_c":-1.0,
"__LactoPanGEM__maltpt_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTG4",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTG5",
"name":"Maltodextrin glucosidase (maltoheptaose)",
"metabolites":{
"__LactoPanGEM__malthp_c":-1.0,
"__LactoPanGEM__malthx_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTG5",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTG6",
"name":"Maltodextrin glucosidase dextrin",
"metabolites":{
"__LactoPanGEM__dextrin_c":-1.0,
"glc__D_c":2.0,
"h2o_c":-2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTG6",
"sbo":"SBO:0000176"
}
},
{
"id":"MLTG7",
"name":"R_Maltodextrin_glucosidase__isomaltose_",
"metabolites":{
"glc__D_c":2.0,
"h2o_c":-1.0,
"isomal_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MLTG7",
"sbo":"SBO:0000176"
}
},
{
"id":"MN6PP",
"name":"mannose 6-phosphate phosphatase",
"metabolites":{
"h2o_c":-1.0,
"man6p_c":-1.0,
"man_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21290 or KJMKFHIL_24330 or KJMKFHIL_13850 or KJMKFHIL_14260 or KJMKFHIL_17470 or KJMKFHIL_12110 or KJMKFHIL_05960 or KJMKFHIL_19680",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MN6PP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MOADCST_1",
"name":"MoaD:cysteine sulfur transferase",
"metabolites":{
"__LactoPanGEM__MCOOH_c":-1.0,
"__LactoPanGEM__MCOSH_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"amp_c":1.0,
"cys__L_c":-1.0,
"h2o_c":-1.0,
"ppi_c":1.0,
"ser__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07920 or KJMKFHIL_07930 or KJMKFHIL_10620 or KJMKFHIL_07530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOADCST_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MPL_1",
"name":"Maltose:phosphate 1-beta-D-glucosyltransferase",
"metabolites":{
"g1p_c":1.0,
"glc__D_c":1.0,
"malt_c":-1.0,
"pi_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MPL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"MTAN",
"name":"methylthioadenosine nucleosidase",
"metabolites":{
"5mta_c":-1.0,
"5mtr_c":1.0,
"ade_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07540",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MTAN",
"rhea":"RHEA:13617",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MTGH",
"name":"R05549",
"metabolites":{
"__LactoPanGEM__mnt_c":-1.0,
"gal_c":1.0,
"h2o_c":-1.0,
"melib_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MTGH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MTHFR3",
"name":"5 10 methylenetetrahydrofolatereductase NADPH",
"metabolites":{
"__LactoPanGEM__5mthf_c":1.0,
"h_c":-2.0,
"mlthf_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MTHFR3",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MTHPTGHM",
"name":"5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase",
"metabolites":{
"__LactoPanGEM__5mthglu_c":-1.0,
"__LactoPanGEM__thglu_c":1.0,
"hcys__L_c":-1.0,
"met__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13320 or KJMKFHIL_23340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MTHPTGHM",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NACYLASPAMH_1",
"name":"N-Acyl-L-aspartate amidohydrolase",
"metabolites":{
"__LactoPanGEM__cmylcoa_c":1.0,
"__LactoPanGEM__nalasp_c":-1.0,
"asp__L_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NACYLASPAMH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NADK_1",
"name":"NAD Kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03750",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NADK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NADPHXD_1",
"name":"NADPHX dehydratase",
"metabolites":{
"__LactoPanGEM__adp_c":-1.0,
"amp_c":1.0,
"h_c":1.0,
"nadph_c":1.0,
"nadphx__S_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":0.0,
"gene_reaction_rule":"KJMKFHIL_04380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NADPHXD_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NADS1_1",
"name":"NAD synthase (nh3)",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"amp_c":1.0,
"dnad_c":-1.0,
"h_c":1.0,
"nad_c":1.0,
"nh4_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NADS1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NAPRT_1",
"name":"NAPRTase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"h_c":-1.0,
"nac_c":-1.0,
"nicrnt_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11670 or KJMKFHIL_02520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NAPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NFORGLUAH",
"name":"N-Formyl-L-glutamate amidohydrolase",
"metabolites":{
"__LactoPanGEM__nforglu_c":-1.0,
"for_c":1.0,
"glu__L_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NFORGLUAH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NMNAT_1",
"name":"nicotinamide-nucleotide adenylyltransferase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"h_c":-1.0,
"nad_c":1.0,
"nmn_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NMNAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"NNAM",
"name":"nicotinamidase",
"metabolites":{
"h2o_c":-1.0,
"nac_c":1.0,
"ncam_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NNAM",
"rhea":"RHEA:14545",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NNAT_1",
"name":"nicotinate-nucleotide adenylyltransferase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"dnad_c":1.0,
"h_c":-1.0,
"nicrnt_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NNAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"NP1_1",
"name":"nucleotide phosphatase",
"metabolites":{
"h_c":-1.0,
"nac_c":-1.0,
"nicrns_c":1.0,
"pi_c":1.0,
"r1p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NP1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"NT5C",
"name":"_5'-nucleotidase",
"metabolites":{
"h2o_c":-1.0,
"nicrns_c":1.0,
"nicrnt_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NT5C",
"rhea":"RHEA:30935",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD1",
"name":"5'-nucleotidase (dUMP)",
"metabolites":{
"dump_c":-1.0,
"duri_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230 or KJMKFHIL_03230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD1",
"rhea":"RHEA:29355",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD10",
"name":"5'-nucleotidase (XMP)",
"metabolites":{
"h2o_c":-1.0,
"pi_c":1.0,
"xmp_c":-1.0,
"xtsn_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD10",
"rhea":"RHEA:28530",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD11",
"name":"5'-nucleotidase (IMP)",
"metabolites":{
"h2o_c":-1.0,
"imp_c":-1.0,
"ins_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD11",
"rhea":"RHEA:27718",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NTD12_1",
"name":"5'-nucleotidase (dIMP)",
"metabolites":{
"__LactoPanGEM__dimp_c":-1.0,
"din_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NTD12_1",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD2",
"name":"5'-nucleotidase (UMP)",
"metabolites":{
"h2o_c":-1.0,
"pi_c":1.0,
"ump_c":-1.0,
"uri_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD2",
"rhea":"RHEA:29359",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD3",
"name":"5'-nucleotidase (dCMP)",
"metabolites":{
"dcmp_c":-1.0,
"dcyt_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230 or KJMKFHIL_03230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD3",
"rhea":"RHEA:29363",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD4",
"name":"5'-nucleotidase (CMP)",
"metabolites":{
"cmp_c":-1.0,
"cytd_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD4",
"rhea":"RHEA:29367",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD5",
"name":"5'-nucleotidase (dTMP)",
"metabolites":{
"dtmp_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0,
"thymd_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230 or KJMKFHIL_03230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD5",
"rhea":"RHEA:11080",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD6",
"name":"5'-nucleotidase (dAMP)",
"metabolites":{
"dad_2_c":1.0,
"damp_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230 or KJMKFHIL_03230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD6",
"rhea":"RHEA:29371",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD7",
"name":"5'-nucleotidase (AMP)",
"metabolites":{
"adn_c":1.0,
"amp_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD7",
"rhea":"RHEA:29375",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD8",
"name":"5'-nucleotidase (dGMP)",
"metabolites":{
"dgmp_c":-1.0,
"dgsn_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230 or KJMKFHIL_03230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD8",
"rhea":"RHEA:29379",
"sbo":"SBO:0000176"
}
},
{
"id":"NTD9",
"name":"5'-nucleotidase (GMP)",
"metabolites":{
"gmp_c":-1.0,
"gsn_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTD9",
"rhea":"RHEA:27714",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NTPP10_1",
"name":"Nucleoside triphosphate pyrophosphorylase (ditp)",
"metabolites":{
"__LactoPanGEM__dimp_c":1.0,
"__LactoPanGEM__ditp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NTPP10_1",
"sbo":"SBO:0000176"
}
},
{
"id":"NTPP11_1",
"name":"Nucleoside triphosphate pyrophosphorylase (xtp)",
"metabolites":{
"h2o_c":-1.0,
"h_c":1.0,
"ppi_c":1.0,
"xmp_c":1.0,
"xtp_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTPP11_1",
"rhea":"RHEA:28610",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NTPTP1",
"name":"Nucleoside triphosphate tripolyhydrolase",
"metabolites":{
"__LactoPanGEM__dgtp_c":-1.0,
"__LactoPanGEM__pppi_c":1.0,
"dgsn_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24760 or KJMKFHIL_09120 or KJMKFHIL_08840 or KJMKFHIL_09640",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NTPTP1:2",
"sbo":"SBO:0000176"
}
},
{
"id":"NTRIRy",
"name":"nitrite reductase (NADPH)",
"metabolites":{
"h2o_c":1.0,
"h_c":-4.0,
"nadp_c":3.0,
"nadph_c":-3.0,
"nh4oh_c":1.0,
"no2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14970 or KJMKFHIL_08360",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NTRIRy:2",
"sbo":"SBO:0000176"
}
},
{
"id":"OAADC",
"name":"oxaloacetate decarboxylase",
"metabolites":{
"co2_c":1.0,
"h_c":-1.0,
"oaa_c":-1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"OAADC",
"rhea":"RHEA:15641",
"sbo":"SBO:0000176"
}
},
{
"id":"OBTFL",
"name":"2-Oxobutanoate formate lyase",
"metabolites":{
"2obut_c":-1.0,
"coa_c":-1.0,
"for_c":1.0,
"ppcoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08490",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"OBTFL",
"rhea":"RHEA:28054",
"sbo":"SBO:0000176"
}
},
{
"id":"OMBZLM",
"name":"2-Octaprenyl-6-methoxy-benzoquinol methylase",
"metabolites":{
"2ombzl_c":-1.0,
"2ommbl_c":1.0,
"ahcys_c":1.0,
"amet_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26080 or KJMKFHIL_01320 or KJMKFHIL_17120",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"OMBZLM",
"sbo":"SBO:0000176"
}
},
{
"id":"OMPDC",
"name":"orotidine-5'-phosphate decarboxylase",
"metabolites":{
"co2_c":1.0,
"h_c":-1.0,
"orot5p_c":-1.0,
"ump_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10210",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"OMPDC",
"rhea":"RHEA:11596",
"sbo":"SBO:0000176"
}
},
{
"id":"ORNCD_2",
"name":"ornithine cyclodeaminase",
"metabolites":{
"nh4_c":1.0,
"orn__L_c":-1.0,
"pro__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ORNCD_2",
"rhea":"RHEA:24368",
"sbo":"SBO:0000176"
}
},
{
"id":"ORNDC",
"name":"Ornithine Decarboxylase",
"metabolites":{
"co2_c":1.0,
"h_c":-1.0,
"orn__L_c":-1.0,
"ptrc_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ORNDC",
"rhea":"RHEA:22964",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PALCOAH",
"name":"palmitoyl-CoA hydrolase",
"metabolites":{
"__LactoPanGEM__lincoa_c":-1.0,
"__LactoPanGEM__linole_c":1.0,
"coa_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PALCOAH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PALCOAH2",
"name":"palmitoyl-CoA hydrolase;",
"metabolites":{
"__LactoPanGEM__5eipenc_c":1.0,
"__LactoPanGEM__icosapcoa_c":-1.0,
"coa_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PALCOAH2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PALCOAH3",
"name":"palmitoyl-CoA hydrolase;",
"metabolites":{
"__LactoPanGEM__dcos4710131619coa_c":-1.0,
"__LactoPanGEM__docohex_c":1.0,
"coa_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PALCOAH3",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PALCOAH4",
"name":"palmitoyl-CoA hydrolase;",
"metabolites":{
"__LactoPanGEM__C03242_c":1.0,
"__LactoPanGEM__itencoa_c":-1.0,
"coa_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PALCOAH4",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PALCOAH5",
"name":"palmitoyl-CoA hydrolase;",
"metabolites":{
"__LactoPanGEM__eitetcoa_c":-1.0,
"arachd_c":1.0,
"coa_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PALCOAH5",
"sbo":"SBO:0000176"
}
},
{
"id":"PAPPT3",
"name":"phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate)",
"metabolites":{
"uagmda_c":1.0,
"udcpp_c":-1.0,
"ugmda_c":-1.0,
"ump_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07720",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PAPPT3",
"rhea":"RHEA:28386",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PC_1",
"name":"Pyruvate carboxylase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2co3_c":-1.0,
"h_c":1.0,
"oaa_c":1.0,
"pi_c":1.0,
"pyr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PC6YM",
"name":"precorrin-6Y C5,15-methyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__pre6b_c":-1.0,
"__LactoPanGEM__pre8_c":1.0,
"ahcys_c":2.0,
"amet_c":-2.0,
"co2_c":1.0,
"h_c":2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PC6YM",
"sbo":"SBO:0000176"
}
},
{
"id":"PDE1",
"name":"3',5'-cyclic-nucleotide phosphodiesterase",
"metabolites":{
"amp_c":1.0,
"camp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03820 or KJMKFHIL_06350 or KJMKFHIL_05220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PDE1",
"rhea":"RHEA:25277",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PENCAC",
"name":"Penicillin acylase",
"metabolites":{
"__LactoPanGEM__6apa_c":1.0,
"for_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"pencil_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PENCAC",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PFK_1",
"name":"Phosphofructokinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__f26bp_c":1.0,
"f6p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19550 or KJMKFHIL_09000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PFK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PFK_2_1",
"name":"ATP:D-tagatose-6-phosphate 1-phosphotransferase_c0",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"tag6p__D_c":-1.0,
"tagdp__D_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09140 or KJMKFHIL_15350 or KJMKFHIL_19550",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PFK_2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PFK_3_1",
"name":"Phosphofructokinase (s7p)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"s17bp_c":1.0,
"s7p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19550 or KJMKFHIL_09000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PFK_3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGGT4",
"name":"peptidoglycan glycosyltransferase",
"metabolites":{
"__LactoPanGEM__PGlac2_c":1.0,
"__LactoPanGEM__uaagtmda_c":-1.0,
"__LactoPanGEM__udcpdp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10710 or KJMKFHIL_09910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGGT4:2",
"sbo":"SBO:0000176"
}
},
{
"id":"PGL",
"name":"6-phosphogluconolactonase",
"metabolites":{
"6pgc_c":1.0,
"6pgl_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PGL",
"rhea":"RHEA:12556",
"sbo":"SBO:0000176"
}
},
{
"id":"PGLYCP",
"name":"Phosphoglycolate phosphatase",
"metabolites":{
"2pglyc_c":-1.0,
"glyclt_c":1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09420 or KJMKFHIL_15300 or KJMKFHIL_01380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PGLYCP",
"rhea":"RHEA:14369",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPAGT_1",
"name":"Poly(glycerol-phosphate) alpha-glucosyltransferase",
"metabolites":{
"__LactoPanGEM__prenoN_acid_c":-1.0,
"__LactoPanGEM__prenoN_ated_c":1.0,
"__LactoPanGEM__udp_c":45.0,
"h_c":45.0,
"udpg_c":-45.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPAGT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP120_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C14:0)",
"metabolites":{
"__LactoPanGEM__pg120_c":1.0,
"__LactoPanGEM__pgp120_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP140_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C14:0)",
"metabolites":{
"__LactoPanGEM__pg140_c":1.0,
"__LactoPanGEM__pgp140_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP140_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP141_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C14:1)",
"metabolites":{
"__LactoPanGEM__pg141_c":1.0,
"__LactoPanGEM__pgp141_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP141_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP160_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C16:0)",
"metabolites":{
"__LactoPanGEM__pg160_c":1.0,
"__LactoPanGEM__pgp160_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP161_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C16:1)",
"metabolites":{
"__LactoPanGEM__pg161_c":1.0,
"__LactoPanGEM__pgp161_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP161_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP180_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C18:0)",
"metabolites":{
"__LactoPanGEM__pg180_c":1.0,
"__LactoPanGEM__pgp180_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGPP181_1",
"name":"phosphatidylglycerol phosphate phosphatase (periplasm, n-C18:1)",
"metabolites":{
"__LactoPanGEM__pg181_c":1.0,
"__LactoPanGEM__pgp181_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGPP181_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA120_1",
"name":"Phosphatidylglycerol synthase (n-C12:0)",
"metabolites":{
"__LactoPanGEM__cdpdddecg_c":-1.0,
"__LactoPanGEM__pgp120_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA140_1",
"name":"Phosphatidylglycerol synthase (n-C14:0)",
"metabolites":{
"__LactoPanGEM__cdpdtdecg_c":-1.0,
"__LactoPanGEM__pgp140_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA140_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA141_1",
"name":"Phosphatidylglycerol synthase (n-C14:1)",
"metabolites":{
"__LactoPanGEM__cdpdtdec7eg_c":-1.0,
"__LactoPanGEM__pgp141_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA141_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA160_1",
"name":"Phosphatidylglycerol synthase (n-C16:0)",
"metabolites":{
"__LactoPanGEM__pgp160_c":1.0,
"cdpdhdecg_c":-1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA160_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA161_1",
"name":"Phosphatidylglycerol synthase (n-C16:1)",
"metabolites":{
"__LactoPanGEM__cdpdhdec9eg_c":-1.0,
"__LactoPanGEM__pgp161_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA161_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA180_1",
"name":"Phosphatidylglycerol synthase (n-C18:0)",
"metabolites":{
"__LactoPanGEM__cdpdodecg_c":-1.0,
"__LactoPanGEM__pgp180_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGSA181_1",
"name":"Phosphatidylglycerol synthase (n-C18:1)",
"metabolites":{
"__LactoPanGEM__cdpdodec11eg_c":-1.0,
"__LactoPanGEM__pgp181_c":1.0,
"cmp_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGSA181_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PKETX_1",
"name":"D-Xylulose 5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)",
"metabolites":{
"actp_c":1.0,
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"h2o_c":1.0,
"pi_c":-1.0,
"xu5p__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04640",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PKETX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PLTAS_1",
"name":"palmitoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
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"__LactoPanGEM__palminsu24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_03870",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PMDPHT:2",
"name":"pyrimidine phosphatase",
"metabolites":{
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"5aprbu_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_19630 or KJMKFHIL_24330 or KJMKFHIL_05960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PMDPHT",
"rhea":"RHEA:25197",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PMEVK_1",
"name":"Phosphomevalonate kinase",
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"__LactoPanGEM__5dpmev_c":1.0,
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},
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"gene_reaction_rule":"KJMKFHIL_13980",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PMEVK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PMPK_1",
"name":"phosphomethylpyrimidine kinase",
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},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15180 or KJMKFHIL_22700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PMPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PNP",
"name":"R_purine_nucleoside_phosphorylase",
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"pi_c":-1.0,
"r1p_c":1.0,
"rnam_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24610",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PNP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PNTK_1",
"name":"Pantothenate Kinase",
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"__LactoPanGEM__adp_c":1.0,
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"pnto__R_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PNTK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"IDPh_1",
"name":"inorganic diphosphatase",
"metabolites":{
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":2.0,
"ppi_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08460 or KJMKFHIL_09500 or KJMKFHIL_01380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"IDPh_1",
"rhea":"RHEA:24576",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPA2_1",
"name":"Inorganic triphosphatase",
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"h2o_c":-1.0,
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},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_18820",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPA2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPADPP1",
"name":"\ufeffPolyphosphate:ADP phosphotransferase",
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"amp_c":1.0,
"pi_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14250",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPADPP1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPADPP2",
"name":"\ufeffPolyphosphate:ADP phosphotransferase",
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"__LactoPanGEM__pppi_c":1.0,
"amp_c":1.0,
"ppi_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14250",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPADPP2",
"sbo":"SBO:0000176"
}
},
{
"id":"PPCDC",
"name":"phosphopantothenoylcysteine decarboxylase",
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"co2_c":1.0,
"h_c":-1.0,
"pan4p_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PPCDC",
"rhea":"RHEA:16793",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPCK_1",
"name":"Phosphoenolpyruvate carboxykinase",
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"__LactoPanGEM__atp_c":-1.0,
"co2_c":1.0,
"oaa_c":-1.0,
"pep_c":1.0
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02670",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPCK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPDK_1",
"name":"Pyruvate,phosphate dikinase.",
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"pi_c":-1.0,
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"pyr_c":-1.0
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18330",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPDK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPNCL2_1",
"name":"Phosphopantothenate-cysteine ligase",
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"4ppcys_c":1.0,
"__LactoPanGEM__ctp_c":-1.0,
"cmp_c":1.0,
"cys__L_c":-1.0,
"h_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00760",
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"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPNCL2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PPOR",
"name":"Phenylpyruvate_oxygen oxidoreductase (hydroxylating,decarboxylating)",
"metabolites":{
"2hyoxplac_c":1.0,
"co2_c":1.0,
"o2_c":-1.0,
"phpyr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06140 or KJMKFHIL_02310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PPOR",
"rhea":"RHEA:31107",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPTT_1",
"name":"trans-pentaprenyltranstransferase",
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"__LactoPanGEM__ipdp_c":-1.0,
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},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_15810 or KJMKFHIL_06370",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__PPTT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRAIS_1",
"name":"Phosphoribosylaminoimidazole synthase",
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"gene_reaction_rule":"KJMKFHIL_01980",
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},
"annotation":{
"biggr":"__LactoPanGEM__PRAIS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PRAMPC_1",
"name":"phosphoribosyl-AMP cyclohydrolase",
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"prbamp_c":-1.0,
"prfp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08330",
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},
"annotation":{
"biggr":"PRAMPC_1",
"rhea":"RHEA:20049",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRASCSi_1",
"name":"Phosphoribosylaminoimidazolesuccinocarboxamide synthase",
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"gene_reaction_rule":"KJMKFHIL_02030",
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},
"annotation":{
"biggr":"__LactoPanGEM__PRASCSi_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRATPP_1",
"name":"Phosphoribosyl-ATP pyrophosphatase",
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"gene_reaction_rule":"KJMKFHIL_08340",
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},
"annotation":{
"biggr":"__LactoPanGEM__PRATPP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PROD2_1",
"name":"Proline dehydrogenase",
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"fadh2_c":1.0,
"h_c":1.0,
"pro__L_c":-1.0,
"pyr5carb_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_10140",
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},
"annotation":{
"biggr":"__LactoPanGEM__PROD2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PROTRS_1",
"name":"Prolyl-tRNA synthetase",
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"__LactoPanGEM__trna_c":-1.0,
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00270",
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},
"annotation":{
"biggr":"__LactoPanGEM__PROTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PSP_L",
"name":"phosphoserine phosphatase (L-serine)",
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"pi_c":1.0,
"pser_c":-1.0,
"ser__L_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_07480 or KJMKFHIL_12530",
"notes":{
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},
"annotation":{
"biggr":"PSP_L",
"rhea":"RHEA:21208",
"sbo":"SBO:0000176"
}
},
{
"id":"PTA2",
"name":"Phosphate acetyltransferase",
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"ppap_c":1.0,
"ppcoa_c":-1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_02830",
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},
"annotation":{
"biggr":"PTA2",
"rhea":"RHEA:28046",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PTPAT_1",
"name":"Phosphopantetheine Adenylyltransferase (Ec 2.7.7.3)",
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"gene_reaction_rule":"KJMKFHIL_07250",
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},
"annotation":{
"biggr":"__LactoPanGEM__PTPAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PYDAMK_1",
"name":"Pyridoxamine Kinase",
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"__LactoPanGEM__atp_c":-1.0,
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"pyam5p_c":1.0,
"pydam_c":-1.0
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"gene_reaction_rule":"KJMKFHIL_23360",
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"annotation":{
"biggr":"__LactoPanGEM__PYDAMK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PYDXK_1",
"name":"Pyridoxal Kinase",
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"pydx_c":-1.0
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"gene_reaction_rule":"KJMKFHIL_23360",
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},
"annotation":{
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"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PYDXNK_1",
"name":"Pyridoxine Kinase",
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"pydxn_c":-1.0
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"annotation":{
"biggr":"__LactoPanGEM__PYDXNK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PYK_1",
"name":"Pyruvate kinase",
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"gene_reaction_rule":"KJMKFHIL_08990",
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"annotation":{
"biggr":"__LactoPanGEM__PYK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PYNP1",
"name":"pyrimidine-nucleoside phosphorylase (cytosine)",
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"cytd_c":1.0,
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"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_06740",
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"annotation":{
"biggr":"PYNP1",
"rhea":"RHEA:52540",
"sbo":"SBO:0000176"
}
},
{
"id":"PYROX_1",
"name":"pyruvate oxidase",
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"annotation":{
"biggr":"PYROX_1",
"rhea":"RHEA:20848",
"sbo":"SBO:0000176"
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},
{
"id":"MALMDA",
"name":"Pyrazinamidase",
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"malm_c":-1.0,
"nh4_c":1.0
},
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"gene_reaction_rule":"KJMKFHIL_11660",
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"annotation":{
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"sbo":"SBO:0000176"
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},
{
"id":"__LactoPanGEM__r0163_1",
"name":"R00621",
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"annotation":{
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"sbo":"SBO:0000176"
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},
{
"id":"__LactoPanGEM__R05220",
"name":"Cob(I)yrinate a,c diamide <=>  Adenosyl cobyrinate a,c diamide",
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"annotation":{
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"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__r0571_1",
"name":"(S)-Methylmalonyl-CoA hydrolase",
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"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_24890",
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"annotation":{
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"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__r0708",
"name":"2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate hydrolase",
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"h2o_c":-1.0
},
"lower_bound":0.0,
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"annotation":{
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"sbo":"SBO:0000176"
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},
{
"id":"__LactoPanGEM__r0737",
"name":"3-Ketolactose galactohydrolase",
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"glc__D_c":1.0,
"h2o_c":-1.0
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"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__r0737",
"sbo":"SBO:0000176"
}
},
{
"id":"RAFGH",
"name":"R_Raffinose_galactohydrolase",
"metabolites":{
"gal_c":1.0,
"h2o_c":-1.0,
"raffin_c":-1.0,
"sucr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12700 or KJMKFHIL_14520",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RAFGH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RBFK_1",
"name":"Riboflavin kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"fmn_c":1.0,
"h_c":1.0,
"ribflv_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RBFK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RBK_1",
"name":"Ribokinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"r5p_c":1.0,
"rib__D_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RBK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RBK_L1_1",
"name":"L-ribulokinase (L-ribulose)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"rbl__L_c":-1.0,
"ru5p__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27800 or KJMKFHIL_23230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RBK_L1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RBLK2_1",
"name":"L-ribulokinase (ribitol)",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__rbt5p_c":1.0,
"h_c":1.0,
"rbt_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27800 or KJMKFHIL_23230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RBLK2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"RHCCE",
"name":"S-ribosylhomocysteine cleavage enzyme",
"metabolites":{
"dhptd_c":1.0,
"hcys__L_c":1.0,
"rhcys_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RHCCE",
"rhea":"RHEA:17753",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__rxn03465_1",
"name":"Acylneuraminyl hydrolase",
"metabolites":{
"__LactoPanGEM__gq1_c":-1.0,
"__LactoPanGEM__gt1b_c":1.0,
"acnam_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19420 or KJMKFHIL_15140",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__rxn03465_1",
"sbo":"SBO:0000176"
}
},
{
"id":"RZ5PP",
"name":"alpha-ribazole 5-phosphate phosphatase",
"metabolites":{
"5prdmbz_c":-1.0,
"h2o_c":-1.0,
"pi_c":1.0,
"rdmbzi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07480",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RZ5PP",
"rhea":"RHEA:24456",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__S6PH_1",
"name":"\ufeffSucrose-6-phosphate hydrolase",
"metabolites":{
"__LactoPanGEM__g6p_c":1.0,
"fru_c":1.0,
"h2o_c":-1.0,
"suc6p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__S6PH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"SAM24MT",
"name":"R_S_adenosyl_methionine_delta_24_sterol_c_methyltransferase",
"metabolites":{
"ahcys_c":1.0,
"amet_c":-1.0,
"fecost_c":1.0,
"h_c":1.0,
"zymst_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08770",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SAM24MT",
"sbo":"SBO:0000176"
}
},
{
"id":"SBP",
"name":"sedoheptulose-bisphosphatase",
"metabolites":{
"h2o_c":-1.0,
"pi_c":1.0,
"s17bp_c":-1.0,
"s7p_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SBP",
"rhea":"RHEA:17461",
"sbo":"SBO:0000176"
}
},
{
"id":"SDPDS",
"name":"succinyl-diaminopimelate desuccinylase",
"metabolites":{
"26dap_LL_c":1.0,
"h2o_c":-1.0,
"sl26da_c":-1.0,
"succ_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02390 or KJMKFHIL_19170 or KJMKFHIL_10690 or KJMKFHIL_11410",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SDPDS",
"rhea":"RHEA:22608",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__SERTRS_1",
"name":"Seryl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__sertrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"ppi_c":1.0,
"ser__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SERTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"SHCHCS3",
"name":"2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase",
"metabolites":{
"2sephchc_c":-1.0,
"2shchc_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13250 or KJMKFHIL_23580 or KJMKFHIL_20630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SHCHCS3",
"rhea":"RHEA:25597",
"sbo":"SBO:0000176"
}
},
{
"id":"SHSL4r",
"name":"O-succinylhomoserine lyase (elimination), reversible",
"metabolites":{
"2obut_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"nh4_c":1.0,
"succ_c":1.0,
"suchms_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27050",
"notes":{
"Confidence Level":"0",
"ECNumbers":"2.5.1.48,\u00a04.2.99.9,\u00a04.3.1"
},
"annotation":{
"biggr":"SHSL4r",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__SLTAS_1",
"name":"stearoyl-lipoteichoic acid synthesis (n-24), linked, glucose substituted",
"metabolites":{
"__LactoPanGEM__stearluc24_c":1.0,
"__LactoPanGEM__stearnsu24_c":-1.0,
"__LactoPanGEM__udp_c":24.0,
"h_c":24.0,
"udpg_c":-24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SLTAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"SPODM_1",
"name":"superoxide dismutase",
"metabolites":{
"h2o2_c":1.0,
"h_c":-2.0,
"o2_c":1.0,
"o2s_c":-2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SPODM_1",
"rhea":"RHEA:20696",
"sbo":"SBO:0000176"
}
},
{
"id":"SSALx",
"name":"succinate-semialdehyde dehydrogenase (NAD)",
"metabolites":{
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0,
"succ_c":1.0,
"sucsal_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SSALx",
"rhea":"RHEA:13217",
"sbo":"SBO:0000176"
}
},
{
"id":"SSALy",
"name":"succinate-semialdehyde dehydrogenase (NADP)",
"metabolites":{
"h2o_c":-1.0,
"h_c":2.0,
"nadp_c":-1.0,
"nadph_c":1.0,
"succ_c":1.0,
"sucsal_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SSALy",
"rhea":"RHEA:13213",
"sbo":"SBO:0000176"
}
},
{
"id":"SUCR",
"name":"sucrose hydrolase",
"metabolites":{
"fru_c":1.0,
"glc__D_c":1.0,
"h2o_c":-1.0,
"sucr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SUCR",
"sbo":"SBO:0000176"
}
},
{
"id":"TDPGDH",
"name":"dTDPglucose 4,6-dehydratase",
"metabolites":{
"dtdp4d6dg_c":1.0,
"dtdpglu_c":-1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12470",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TDPGDH",
"rhea":"RHEA:17221",
"sbo":"SBO:0000176"
}
},
{
"id":"THDPS",
"name":"tetrahydrodipicolinate succinylase",
"metabolites":{
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"h2o_c":-1.0,
"sl2a6o_c":1.0,
"succoa_c":-1.0,
"thdp_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THDPS",
"rhea":"RHEA:17325",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__THFGLUS_1",
"name":"TetrahydrofolateL glutamate gamma ligase ADP forming",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__thfglu_c":1.0,
"glu__L_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"thf_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__THFGLUS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__THIORDXi",
"name":"Hydrogen peroxide reductase (thioredoxin)",
"metabolites":{
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o2_c":-1.0,
"h2o_c":2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13560 or KJMKFHIL_24740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__THIORDXi",
"sbo":"SBO:0000176"
}
},
{
"id":"THMt2",
"name":"R_Thiamine_transport_in_via_proton_symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"thm_c":1.0,
"thm_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02060",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THMt2",
"sbo":"SBO:0000655"
}
},
{
"id":"THRS_2",
"name":"threonine synthase",
"metabolites":{
"h2o_c":-1.0,
"phom_c":-1.0,
"pi_c":1.0,
"thr__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THRS_2",
"rhea":"RHEA:10840",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__THRTRS_1",
"name":"Threonyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__thrtrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"ppi_c":1.0,
"thr__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01510",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__THRTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TMDK1_1",
"name":"Thymidine Kinase (ATP:Thymidine)",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"dtmp_c":1.0,
"h_c":1.0,
"thymd_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10900",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__TMDK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TMDK2_1",
"name":"thymidine kinase (GTP:Thymidine)",
"metabolites":{
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"__LactoPanGEM__gtp_c":-1.0,
"dtmp_c":1.0,
"h_c":1.0,
"thymd_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TMDK2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TMDPK_1",
"name":"Thiamine diphosphokinase",
"metabolites":{
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"__LactoPanGEM__thmpp_c":1.0,
"amp_c":1.0,
"h_c":1.0,
"thm_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00680",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TMDPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"TMDS",
"name":"thymidylate synthase",
"metabolites":{
"dhf_c":1.0,
"dtmp_c":1.0,
"dump_c":-1.0,
"mlthf_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08770",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TMDS",
"rhea":"RHEA:12104",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TMK_1",
"name":"Thiamine kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"thm_c":-1.0,
"thmmp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01660 or KJMKFHIL_22690",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TMK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"TMN",
"name":"R_thiaminase",
"metabolites":{
"4ahmmp_c":1.0,
"4mhetz_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"thm_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TMN",
"rhea":"RHEA:17509",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TMPPP",
"name":"Thiamine-phosphate diphosphorylase",
"metabolites":{
"4mpetz_c":-1.0,
"__LactoPanGEM__2mahmp_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0,
"thmmp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22690",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TMPPP",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TPRDCOAS_1",
"name":"Triphosphoribosyl-dephospho-CoA synthase",
"metabolites":{
"__LactoPanGEM__2tpr3dpcoa_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"ade_c":1.0,
"dpcoa_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TPRDCOAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TPS_1",
"name":"thiamine phosphate synthase",
"metabolites":{
"__LactoPanGEM__2mahmp_c":-1.0,
"__LactoPanGEM__C20246_c":-1.0,
"co2_c":1.0,
"ppi_c":1.0,
"thmmp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22690",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TPS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TRDR_1",
"name":"thioredoxin reductase (NADPH)",
"metabolites":{
"__LactoPanGEM__trdox_c":-1.0,
"__LactoPanGEM__trdrd_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03290",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TRDR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TRE6PH_1",
"name":"trehalose-6-phosphate hydrolase",
"metabolites":{
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"glc__D_c":1.0,
"h2o_c":-1.0,
"tre6p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12880 or KJMKFHIL_02990 or KJMKFHIL_19290 or KJMKFHIL_23290 or KJMKFHIL_17390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TRE6PH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"TREpts",
"name":"trehalose transport via PEP:Pyr PTS",
"metabolites":{
"pep_c":-1.0,
"pyr_c":1.0,
"tre6p_c":1.0,
"tre_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02080 or KJMKFHIL_02090 or KJMKFHIL_23280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TREpts",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__TRNASTr_1",
"name":"\ufefftRNA sulfurtransferase",
"metabolites":{
"__LactoPanGEM__C15811_c":1.0,
"__LactoPanGEM__C15812_c":-1.0,
"__LactoPanGEM__C15813_c":-1.0,
"__LactoPanGEM__C15814_c":1.0,
"amp_c":1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07920",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TRNASTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TRO2EHL",
"name":"Trans-Octodec-2-enoyl-ACP hydro-lyase",
"metabolites":{
"__LactoPanGEM__3hodacp_c":-1.0,
"__LactoPanGEM__to2eacp_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13060 or KJMKFHIL_12970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TRO2EHL:2",
"sbo":"SBO:0000176"
}
},
{
"id":"CYSDS",
"name":"Cysteine Desulfhydrase",
"metabolites":{
"cys__L_c":-1.0,
"h2o_c":-1.0,
"h2s_c":1.0,
"h_c":1.0,
"nh4_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27050 or KJMKFHIL_22520 or KJMKFHIL_03830",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYSDS",
"rhea":"RHEA:24931",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TRPTRS_1",
"name":"Tryptophanyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__trna_c":-1.0,
"__LactoPanGEM__trptrna_c":1.0,
"amp_c":1.0,
"ppi_c":1.0,
"trp__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TRPTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TYRTRS_1",
"name":"Tyrosyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__trna_c":-1.0,
"__LactoPanGEM__tyrtrna_c":1.0,
"amp_c":1.0,
"ppi_c":1.0,
"tyr__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TYRTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__U23GAAT_1",
"name":"UDP-3-O-(3-hydroxymyristoyl)glucosamine acyltransferase",
"metabolites":{
"__LactoPanGEM__3hmrsacp_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__u23ga_c":1.0,
"h_c":2.0,
"u3hga_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24320 or KJMKFHIL_05320 or KJMKFHIL_27120",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__U23GAAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAAGDS_1",
"name":"UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase",
"metabolites":{
"26dap__M_c":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"uamag_c":-1.0,
"ugmd_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAAGDS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAAGLS1_1",
"name":"UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-lysine synthetase (alpha-glutamate)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__uAgl_c":1.0,
"h_c":2.0,
"lys__L_c":-1.0,
"pi_c":1.0,
"uamag_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23180",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAAGLS1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"UAGCVT_1",
"name":"UDP-N-acetylglucosamine 1-carboxyvinyltransferase",
"metabolites":{
"pep_c":-1.0,
"pi_c":1.0,
"uaccg_c":1.0,
"uacgam_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UAGCVT_1",
"rhea":"RHEA:18681",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAGDP_1",
"name":"UDP-N-acetylglucosamine diphosphorylase",
"metabolites":{
"__LactoPanGEM__utp_c":-1.0,
"acgam1p_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0,
"uacgam_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19130",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAGDP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAGPT2_1",
"name":"UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase",
"metabolites":{
"__LactoPanGEM__uaGgla_c":-1.0,
"__LactoPanGEM__uaaGgla_c":1.0,
"__LactoPanGEM__udp_c":1.0,
"h_c":1.0,
"uacgam_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAGPT2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAMAGS_1",
"name":"UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"glu__D_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"uama_c":-1.0,
"uamag_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAMAGS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAMAS_1",
"name":"UDP-N-acetylmuramoyl-L-alanine synthetase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"ala__L_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"uama_c":1.0,
"uamr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01600",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAMAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"UAPGR",
"name":"UDP-N-acetylenolpyruvoylglucosamine reductase",
"metabolites":{
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"uaccg_c":-1.0,
"uamr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UAPGR",
"rhea":"RHEA:12248",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UDCPDP_1",
"name":"undecaprenyl-diphosphatase",
"metabolites":{
"__LactoPanGEM__udcpdp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"udcpp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UDCPDP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UDCPDPS_1",
"name":"Undecaprenyl diphosphate synthase",
"metabolites":{
"__LactoPanGEM__frdp_c":-1.0,
"__LactoPanGEM__ipdp_c":-8.0,
"__LactoPanGEM__udcpdp_c":1.0,
"ppi_c":8.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UDCPDPS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UDCPK_1",
"name":"undecaprenol kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__udcp_c":-1.0,
"h_c":1.0,
"udcpp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09620",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UDCPK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UGMDDS2_1",
"name":"UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-lactate synthetase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__alalac_c":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"ugmd_c":-1.0,
"ugmda_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UGMDDS2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UI45AH_1",
"name":"R04857",
"metabolites":{
"__LactoPanGEM__a45imzc_c":1.0,
"__LactoPanGEM__u45imzc_c":-1.0,
"co2_c":1.0,
"h2o_c":-1.0,
"h_c":-2.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UI45AH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UPPRT_1",
"name":"Uracil phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"ppi_c":1.0,
"ump_c":1.0,
"ura_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10850",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UPPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"URACPAH",
"name":"peroxyureidoacrylate hydrolase",
"metabolites":{
"cbm_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"poaac_c":1.0,
"uracp_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"URACPAH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UTPFPPTr_1",
"name":"UTP:D-fructose-6-phosphate 1-phosphotransferase",
"metabolites":{
"__LactoPanGEM__f26bp_c":1.0,
"__LactoPanGEM__udp_c":1.0,
"__LactoPanGEM__utp_c":-1.0,
"f6p_c":-1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19550 or KJMKFHIL_09000",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UTPFPPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__VALTRS_1",
"name":"Valyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__trna_c":-1.0,
"__LactoPanGEM__valtrna_c":1.0,
"amp_c":1.0,
"ppi_c":1.0,
"val__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__VALTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__XPPT_1",
"name":"xanthine phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__prpp_c":-1.0,
"ppi_c":1.0,
"xan_c":-1.0,
"xmp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21480",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__XPPT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__THMabc_1",
"name":"thiamine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"thm_c":1.0,
"thm_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22640 or KJMKFHIL_26650",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__THMabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__HMPabc_1",
"name":"Hydroxymethylpyrimidine ABC transporter",
"metabolites":{
"4ahmmp_c":1.0,
"__LactoPanGEM__4ahmmp_e":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22640 or KJMKFHIL_22630 or KJMKFHIL_26650",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMPabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__SPMDabc_1",
"name":"spermidine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"spmd_c":1.0,
"spmd_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02700 or KJMKFHIL_02880 or KJMKFHIL_02720 or KJMKFHIL_02730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SPMDabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ILEabc_1",
"name":"L-isoleucine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"ile__L_c":1.0,
"ile__L_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27090 or KJMKFHIL_24670 or KJMKFHIL_25990 or KJMKFHIL_24700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ILEabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__VALabc_1",
"name":"L-valine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"val__L_c":1.0,
"val__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27090 or KJMKFHIL_24670 or KJMKFHIL_25990 or KJMKFHIL_24700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__VALabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__LEUabc_1",
"name":"L-leucine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"leu__L_c":1.0,
"leu__L_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27090 or KJMKFHIL_24670 or KJMKFHIL_25990 or KJMKFHIL_24700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LEUabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"SERD_L",
"name":"L-serine deaminase",
"metabolites":{
"nh4_c":1.0,
"pyr_c":1.0,
"ser__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10460 or KJMKFHIL_10470",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SERD_L",
"rhea":"RHEA:19169",
"sbo":"SBO:0000176"
}
},
{
"id":"THRD_L",
"name":"L-threonine deaminase",
"metabolites":{
"2obut_c":1.0,
"nh4_c":1.0,
"thr__L_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10460 or KJMKFHIL_10470 or KJMKFHIL_06460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THRD_L",
"rhea":"RHEA:22108",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PLTASUDALAS_1",
"name":"palmitoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__palmiluc24_c":-1.0,
"__LactoPanGEM__palmtcaala__D_c":1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MLTASUDALAS_1",
"name":"myristoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__myrisluc24_c":-1.0,
"__LactoPanGEM__myrstcaala__D_c":1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":26.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__SLTAS24UDALAS_1",
"name":"stearoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__stearluc24_c":-1.0,
"__LactoPanGEM__sttcaala__D_c":1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SLTAS24UDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHEDSUDALAS_1",
"name":"isoheptadecanoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__i17tcaala__D_c":1.0,
"__LactoPanGEM__isoheluc24_c":-1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHEDSUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIHEDLTASUDALAS_1",
"name":"anteisoheptadecanoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__ai17tcaala__D_c":1.0,
"__LactoPanGEM__anteiluc24_c":-1.0,
"__LactoPanGEM__atp_c":-24.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIHEDLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ITEDLTASUDALAS_1",
"name":"isotetradecanoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__i14tcaala__D_c":1.0,
"__LactoPanGEM__isoteluc24_c":-1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ITEDLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IPEDLTASUDALAS_1",
"name":"isopentadecanoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__i15tcaala__D_c":1.0,
"__LactoPanGEM__isopeluc24_c":-1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IPEDLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIPEDLTASUDALAS_1",
"name":"anteisopentadecanoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__ai15tca1_c":-1.0,
"__LactoPanGEM__ai15tcaala__D_c":1.0,
"__LactoPanGEM__atp_c":-24.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":23.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIPEDLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IHXDLTASUDALAS_1",
"name":"isohexadecanoyl-lipoteichoic acid synthesis (n-24), unlinked, D-alanine substituted",
"metabolites":{
"__LactoPanGEM__atp_c":-24.0,
"__LactoPanGEM__i16tca1_c":-1.0,
"__LactoPanGEM__i16tcaala__D_c":1.0,
"ala__D_c":-24.0,
"amp_c":24.0,
"h_c":24.0,
"ppi_c":24.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13600 or KJMKFHIL_13580",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IHXDLTASUDALAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACCOAC_2",
"name":"Acetyl-CoA carboxylase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"accoa_c":-1.0,
"h2co3_c":-1.0,
"h_c":1.0,
"malcoa_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12940 or KJMKFHIL_12930 or KJMKFHIL_12980",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACCOAC_2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ACCOAC_1_1",
"name":"Acetyl-CoA:carbon-dioxide ligase (ADP-forming)",
"metabolites":{
"__LactoPanGEM__btnCCP_c":1.0,
"__LactoPanGEM__cbtnCCP_c":-1.0,
"accoa_c":-1.0,
"malcoa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12940 or KJMKFHIL_12930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACCOAC_1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RNDR4",
"name":"Ribonucleoside-Diphosphate Reductase (UDP)",
"metabolites":{
"__LactoPanGEM__dudp_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"__LactoPanGEM__udp_c":-1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10030 or KJMKFHIL_03290 or KJMKFHIL_13560 or KJMKFHIL_01630 or KJMKFHIL_24740 or KJMKFHIL_10020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNDR4:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RNDR3",
"name":"Ribonucleoside-Diphosphate Reductase (CDP)",
"metabolites":{
"__LactoPanGEM__cdp_c":-1.0,
"__LactoPanGEM__dcdp_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10030 or KJMKFHIL_03290 or KJMKFHIL_13560 or KJMKFHIL_01630 or KJMKFHIL_24740 or KJMKFHIL_10020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNDR3:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__K_EXP_1",
"name":"potassium export",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"k_c":1.0,
"k_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18310 or KJMKFHIL_21020 or KJMKFHIL_07030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__K_EXP_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__PIabc_1",
"name":"phosphate transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":2.0,
"pi_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03370 or KJMKFHIL_07600 or KJMKFHIL_03410 or KJMKFHIL_03400 or KJMKFHIL_03390 or KJMKFHIL_03380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PIabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ARGabc_1",
"name":"L-arginine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"arg__L_c":1.0,
"arg__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07800 or KJMKFHIL_24230 or KJMKFHIL_17560 or KJMKFHIL_09170 or KJMKFHIL_07810 or KJMKFHIL_07790 or KJMKFHIL_24130",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ARGabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLNabc_1",
"name":"L-glutamine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"gln__L_c":1.0,
"gln__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17950 or KJMKFHIL_24230 or KJMKFHIL_21000 or KJMKFHIL_09170 or KJMKFHIL_24250 or KJMKFHIL_24130 or KJMKFHIL_07800 or KJMKFHIL_17920 or KJMKFHIL_17930 or KJMKFHIL_17940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLNabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__MNabc",
"name":"manganese transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"mn2_c":1.0,
"mn2_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21220 or KJMKFHIL_21120 or KJMKFHIL_21170 or KJMKFHIL_21200 or KJMKFHIL_21210",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MNabc",
"sbo":"SBO:0000655"
}
},
{
"id":"CITL",
"name":"Citrate lyase",
"metabolites":{
"ac_c":1.0,
"cit_c":-1.0,
"oaa_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16850 or KJMKFHIL_16860 or KJMKFHIL_16870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CITL",
"rhea":"RHEA:10760",
"sbo":"SBO:0000176"
}
},
{
"id":"CYTBO3",
"name":"cytochrome oxidase bo3 (ubiquinol-8: 2.5 protons)",
"metabolites":{
"h2o_c":1.0,
"h_c":-2.5,
"h_e":2.5,
"o2_c":-0.5,
"q8_c":1.0,
"q8h2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25660 or KJMKFHIL_06720 or KJMKFHIL_25670 or KJMKFHIL_06710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYTBO3",
"sbo":"SBO:0000655"
}
},
{
"id":"CYTBD2",
"name":"cytochrome oxidase bd (menaquinol-8: 2 protons)",
"metabolites":{
"h2o_c":1.0,
"h_c":-2.0,
"h_e":2.0,
"mql8_c":-1.0,
"mqn8_c":1.0,
"o2_c":-0.5
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25660 or KJMKFHIL_06720 or KJMKFHIL_25670 or KJMKFHIL_06710",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYTBD2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__PHETRS_1",
"name":"Phenylalanyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__phetrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"phe__L_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01190 or KJMKFHIL_01200",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PHETRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"TRPS2",
"name":"tryptophan synthase (indole)",
"metabolites":{
"h2o_c":1.0,
"indole_c":-1.0,
"ser__L_c":-1.0,
"trp__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05450 or KJMKFHIL_05460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TRPS2",
"sbo":"SBO:0000176"
}
},
{
"id":"TRPS1",
"name":"tryptophan synthase (indoleglycerol phosphate)",
"metabolites":{
"3ig3p_c":-1.0,
"g3p_c":1.0,
"h2o_c":1.0,
"ser__L_c":-1.0,
"trp__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05450 or KJMKFHIL_05460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TRPS1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAS100_1",
"name":"3-oxoacyl-[acyl-carrier-protein] synthase (n-C10:0)",
"metabolites":{
"__LactoPanGEM__3odecacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"__LactoPanGEM__ocacp_c":-1.0,
"co2_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAS100_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FAS2_7_1_1",
"name":"Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__3opalmacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"__LactoPanGEM__tdeacp_c":-1.0,
"co2_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FAS2_7_1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAS140",
"name":"3-oxoacyl-[acyl-carrier-protein] synthase (n-C14:0)",
"metabolites":{
"__LactoPanGEM__3omrsacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__ddcaacp_c":-1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAS140:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAS60",
"name":"3-oxoacyl-[acyl-carrier-protein] synthase (n-C6:0)",
"metabolites":{
"__LactoPanGEM__3ohexacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__butacp_c":-1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAS60:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__KAS14_1",
"name":"Beta-ketoacyl-ACP synthase",
"metabolites":{
"__LactoPanGEM__acacp_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__actacp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__KAS14_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAS120_1",
"name":"3-oxoacyl-[acyl-carrier-protein] synthase (n-C12:0)",
"metabolites":{
"__LactoPanGEM__3oddecacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__dcaacp_c":-1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAS120_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAS80",
"name":"3-oxoacyl-[acyl-carrier-protein] synthase (n-C8:0)",
"metabolites":{
"__LactoPanGEM__3ooctacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__hexacp_c":-1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAS80:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4M3OHAT_1",
"name":"4-methyl-3-oxo-hexanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__2mbutacp_c":-1.0,
"__LactoPanGEM__4m3ohexacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4M3OHAT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4MHEAMA",
"name":"4-methyl-hexanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__4methexacp_c":-1.0,
"__LactoPanGEM__6m3oacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4MHEAMA:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__6MOAMCA",
"name":"6-methyl-octanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__6moacp_c":-1.0,
"__LactoPanGEM__8m3odacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__6MOAMCA:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__8MDAM",
"name":"8-methyl-decanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__3oddecacp_c":1.0,
"__LactoPanGEM__8mdacp_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__8MDAM:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__10MDOD",
"name":"10-methyl-dodecanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__10mdacp_c":-1.0,
"__LactoPanGEM__123oxtacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__10MDOD:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MTDACP",
"name":"12-methyl-tetra-decanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__12methedec_c":-1.0,
"__LactoPanGEM__14m3ohdacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MTDACP:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3METHMCAC_1",
"name":"3-methylbutanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__5m3hhacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__isovacp_c":-1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3METHMCAC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__5MHACC",
"name":"5-methyl-hexanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__3mehacp_c":-1.0,
"__LactoPanGEM__7me3oxoacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__5MHACC:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__7MOACA",
"name":"7-methyl-octanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__7moacp_c":-1.0,
"__LactoPanGEM__9m3odacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__7MOACA:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__9MDAM",
"name":"9-methyl-decanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__11m3odacp_c":1.0,
"__LactoPanGEM__9mdacp_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__9MDAM:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__11MDAMCA",
"name":"11-methyl-dodecanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__11mdacp_c":-1.0,
"__LactoPanGEM__13m3otdacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__11MDAMCA:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__13MTDAM",
"name":"13-methyl-tetra-decanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__13mtdacp_c":-1.0,
"__LactoPanGEM__15m3ohdacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__13MTDAM:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ISOGL3P_1",
"name":"2-methylpropionyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__4m3opacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__isobutacp_c":-1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ISOGL3P_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4METPAC",
"name":"4-methyl-pentanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__4mpentacp_c":-1.0,
"__LactoPanGEM__6m3ohacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4METPAC:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__6MHACPA",
"name":"6-methyl-heptanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__6mhacp_c":-1.0,
"__LactoPanGEM__8m3oxacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__6MHACPA:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__8MNAMC",
"name":"8-methyl-nonanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__10m3ouacp_c":1.0,
"__LactoPanGEM__8mcacp_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__8MNAMC:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__10MUAM",
"name":"10-methyl-undecanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__10muacp_c":-1.0,
"__LactoPanGEM__12m3otacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__10MUAM:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__12MTACPM",
"name":"12-methyl-tridecanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
"__LactoPanGEM__12mtacp_c":-1.0,
"__LactoPanGEM__14m3opacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"co2_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__12MTACPM:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OAS180_1",
"name":"3-oxoacyl-[acyl-carrier-protein] synthase (n-C18:0)",
"metabolites":{
"__LactoPanGEM__3ooctdacp_c":1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__malacp_c":-1.0,
"__LactoPanGEM__palmacp_c":-1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12990 or KJMKFHIL_13040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3OAS180_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__METSabc_1",
"name":"L methionine S oxide transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"metsox_S__L_c":1.0,
"metsox_S__L_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21000 or KJMKFHIL_10650 or KJMKFHIL_10670 or KJMKFHIL_10680 or KJMKFHIL_17310 or KJMKFHIL_02440 or KJMKFHIL_25560 or KJMKFHIL_10660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METSabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__METSRabc_1",
"name":"L methionine R oxide transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__metox__R_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21000 or KJMKFHIL_10650 or KJMKFHIL_10670 or KJMKFHIL_10680 or KJMKFHIL_17310 or KJMKFHIL_02440 or KJMKFHIL_25560 or KJMKFHIL_10660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METSRabc_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CBPS_1",
"name":"Carbamoyl-Phosphate Synthase (Glutamine-Hydrolysing)",
"metabolites":{
"__LactoPanGEM__adp_c":2.0,
"__LactoPanGEM__atp_c":-2.0,
"cbp_c":1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2co3_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10180 or KJMKFHIL_10190",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CBPS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYTRS_1",
"name":"Glycyl-tRNA synthetase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__glytrna_c":1.0,
"__LactoPanGEM__trna_c":-1.0,
"amp_c":1.0,
"gly_c":-1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09690 or KJMKFHIL_09680",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYTRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BUTSO3abcpp_1",
"name":"Butanesulfonate transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"butso3_c":1.0,
"butso3_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20930 or KJMKFHIL_20940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BUTSO3abcpp_1",
"sbo":"SBO:0000655"
}
},
{
"id":"GLYCL",
"name":"Glycine Cleavage System",
"metabolites":{
"co2_c":1.0,
"gly_c":-1.0,
"mlthf_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"nh4_c":1.0,
"thf_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06500 or KJMKFHIL_07350 or KJMKFHIL_10250 or KJMKFHIL_10700 or KJMKFHIL_10280 or KJMKFHIL_07340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLYCL",
"rhea":"RHEA:27758",
"sbo":"SBO:0000176"
}
},
{
"id":"PDH",
"name":"pyruvate dehydrogenase",
"metabolites":{
"accoa_c":1.0,
"co2_c":1.0,
"coa_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"pyr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1.0,
"gene_reaction_rule":"KJMKFHIL_06500 or KJMKFHIL_07350 or KJMKFHIL_10250 or KJMKFHIL_10280 or KJMKFHIL_07360 or KJMKFHIL_07340 or KJMKFHIL_07370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PDH",
"rhea":"RHEA:28042",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLNSP2_1",
"name":"Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine:ammonia ligase (ADP-forming)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__uaaGgla_c":-1.0,
"__LactoPanGEM__uaaGgtla_c":1.0,
"h_c":1.0,
"nh4_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23030 or KJMKFHIL_10910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLNSP2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IG3PS_1",
"name":"Imidazole-glycerol-3-phosphate synthase",
"metabolites":{
"__LactoPanGEM__prlp_c":-1.0,
"aicar_c":1.0,
"eig3p_c":1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08320 or KJMKFHIL_08300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IG3PS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRFGS_1",
"name":"Phosphoribosylformylglycinamidine synthase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"fgam_c":-1.0,
"fpram_c":1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02020 or KJMKFHIL_02000 or KJMKFHIL_02010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PRFGS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MNLabc_1",
"name":"Mannitol efflux via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"mnl_c":-1.0,
"mnl_e":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17490 or KJMKFHIL_20510 or KJMKFHIL_18720 or KJMKFHIL_19880 or KJMKFHIL_03250 or KJMKFHIL_02440 or KJMKFHIL_02610 or KJMKFHIL_25560",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MNLabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__PROabc_1",
"name":"L-proline transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"pro__L_c":1.0,
"pro__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17590 or KJMKFHIL_17580 or KJMKFHIL_27060 or KJMKFHIL_17570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PROabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CYSabc_1",
"name":"L-cysteine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"cys__L_c":1.0,
"cys__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27070 or KJMKFHIL_27060 or KJMKFHIL_09170 or KJMKFHIL_24130",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYSabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ASCBpts_1",
"name":"L-ascorbate transport via PEP:Pyr PTS",
"metabolites":{
"__LactoPanGEM__ascb6p_c":1.0,
"__LactoPanGEM__ascb__L_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25440 or KJMKFHIL_12050 or KJMKFHIL_12060 or KJMKFHIL_12070 or KJMKFHIL_27290 or KJMKFHIL_27300 or KJMKFHIL_02080 or KJMKFHIL_02090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ASCBpts_1",
"sbo":"SBO:0000655"
}
},
{
"id":"SBTpts",
"name":"D-sorbitol transport via PEP:Pyr PTS",
"metabolites":{
"pep_c":-1.0,
"pyr_c":1.0,
"sbt6p_c":1.0,
"sbt__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12200 or KJMKFHIL_02080 or KJMKFHIL_02090 or KJMKFHIL_12160",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SBTpts",
"sbo":"SBO:0000655"
}
},
{
"id":"LACpts",
"name":"Lactose transport via PEP:Pyr PTS",
"metabolites":{
"lac6p_c":1.0,
"lcts_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26750 or KJMKFHIL_02080 or KJMKFHIL_02090 or KJMKFHIL_26730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LACpts",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__METDabc_1",
"name":"D-methionine transport via ABC system",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"met__D_c":1.0,
"met__D_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10650 or KJMKFHIL_21000 or KJMKFHIL_10670 or KJMKFHIL_10680 or KJMKFHIL_17310 or KJMKFHIL_02440 or KJMKFHIL_25560 or KJMKFHIL_10660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METDabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__METabc_1",
"name":"L-methionine transport via ABC system",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"met__L_c":1.0,
"met__L_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10650 or KJMKFHIL_21000 or KJMKFHIL_10670 or KJMKFHIL_10680 or KJMKFHIL_17310 or KJMKFHIL_02440 or KJMKFHIL_25560 or KJMKFHIL_10660",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLYBabc",
"name":"Glycine betaine transport via ABC system",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"glyb_c":1.0,
"glyb_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05530 or KJMKFHIL_05540 or KJMKFHIL_05550 or KJMKFHIL_05560 or KJMKFHIL_06170 or KJMKFHIL_02440 or KJMKFHIL_06160 or KJMKFHIL_06150 or KJMKFHIL_27930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYBabc",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ARSENBabc",
"name":"Arsenobetaine transport in via ABC system",
"metabolites":{
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"__LactoPanGEM__arsenb_c":1.0,
"__LactoPanGEM__arsenb_e":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05530 or KJMKFHIL_05540 or KJMKFHIL_05550 or KJMKFHIL_05560 or KJMKFHIL_06170 or KJMKFHIL_02440 or KJMKFHIL_06160 or KJMKFHIL_06150 or KJMKFHIL_27930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ARSENBabc",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CHLabc",
"name":"choline transport via ABC system",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"chol_c":1.0,
"chol_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02440 or KJMKFHIL_05530 or KJMKFHIL_05540 or KJMKFHIL_05550 or KJMKFHIL_05560",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CHLabc",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc1_1",
"name":"Dipeptide transport via ABC system ala asp",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"ala_L_asp__L_c":1.0,
"ala_L_asp__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc1_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc10_1",
"name":"Dipeptide transport via ABC system gly glu",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_glu__L_c":1.0,
"__LactoPanGEM__gly_glu__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc10_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc11_1",
"name":"Dipeptide transport via ABC system gly met",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
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"__LactoPanGEM__gly_met_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc11_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc12_1",
"name":"Dipeptide transport via ABC system met ala",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__met_L_ala__L_c":1.0,
"__LactoPanGEM__met_L_ala__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc12_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc13_1",
"name":"Dipeptide transport via ABC system gly asp",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_asp__L_c":1.0,
"__LactoPanGEM__gly_asp__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc13_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc14_1",
"name":"Dipeptide transport via ABC system gly pro L",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_pro__L_c":1.0,
"__LactoPanGEM__gly_pro__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc14_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc15_1",
"name":"Dipeptide transport via ABC system cgly",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"cgly_c":1.0,
"cgly_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc15_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc2_1",
"name":"Dipeptide transport via ABC system ala gln",
"metabolites":{
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"__LactoPanGEM__ala_gln_c":1.0,
"__LactoPanGEM__ala_gln_e":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
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"pi_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc2_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc3_1",
"name":"Dipeptide transport via ABC system ala glu",
"metabolites":{
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"__LactoPanGEM__ala_L_glu__L_c":1.0,
"__LactoPanGEM__ala_L_glu__L_e":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
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"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc3_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc4_1",
"name":"Dipeptide transport via ABC system ala gly",
"metabolites":{
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"L_alagly_e":-1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
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"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc4_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc5_1",
"name":"Dipeptide transport via ABC system ala his",
"metabolites":{
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"__LactoPanGEM__ala_his_c":1.0,
"__LactoPanGEM__ala_his_e":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
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"pi_c":1.0
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"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc5_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc6_1",
"name":"Dipeptide transport via ABC system ala leu",
"metabolites":{
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"__LactoPanGEM__ala_leu_c":1.0,
"__LactoPanGEM__ala_leu_e":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
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"pi_c":1.0
},
"lower_bound":0.0,
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"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc6_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc7_1",
"name":"Dipeptide transport via ABC system ala thr",
"metabolites":{
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"__LactoPanGEM__ala_L_thr__L_c":1.0,
"__LactoPanGEM__ala_L_thr__L_e":-1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc7_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc8_1",
"name":"Dipeptide transport via ABC system gly asn",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_asn__L_c":1.0,
"__LactoPanGEM__gly_asn__L_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc8_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DIPEPabc9_1",
"name":"Dipeptide transport via ABC system gly gln",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_gln_c":1.0,
"__LactoPanGEM__gly_gln_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16590 or KJMKFHIL_16600 or KJMKFHIL_04630 or KJMKFHIL_10380 or KJMKFHIL_12570 or KJMKFHIL_12560 or KJMKFHIL_12550 or KJMKFHIL_12540 or KJMKFHIL_00600 or KJMKFHIL_00610 or KJMKFHIL_00580 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DIPEPabc9_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLYCYSabc_1",
"name":"Gly-Cys ABC transporters",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_cys_c":1.0,
"__LactoPanGEM__gly_cys_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12560 or KJMKFHIL_04630 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_10380 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYCYSabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLYLEUtr_1",
"name":"Gly-Leu ABC transporters",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_leu_c":1.0,
"__LactoPanGEM__gly_leu_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12560 or KJMKFHIL_04630 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_10380 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYLEUtr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLYPHEtr_1",
"name":"Gly-Phe ABC transporters",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_phe_c":1.0,
"__LactoPanGEM__gly_phe_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12560 or KJMKFHIL_04630 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_10380 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYPHEtr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLYTYRabc_1",
"name":"Gly-Try ABC transporters",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__gly_tyr_c":1.0,
"__LactoPanGEM__gly_tyr_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12560 or KJMKFHIL_04630 or KJMKFHIL_10390 or KJMKFHIL_22600 or KJMKFHIL_12580 or KJMKFHIL_10380 or KJMKFHIL_16560 or KJMKFHIL_16570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYTYRabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__RIBabc",
"name":"D-ribose transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0,
"rib__D_c":1.0,
"rib__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22770 or KJMKFHIL_22750 or KJMKFHIL_22760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RIBabc",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DHAK_1",
"name":"Dihydroxyacetone kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"dha_c":-1.0,
"dhap_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17250 or KJMKFHIL_17230 or KJMKFHIL_17240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DHAK_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MOD",
"name":"R07599",
"metabolites":{
"3mob_c":-1.0,
"__LactoPanGEM__2mhop_c":1.0,
"__LactoPanGEM__thmpp_c":-1.0,
"co2_c":1.0,
"h_c":-2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10260 or KJMKFHIL_10270",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOD",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__OICD",
"name":"2-oxoisocaproate dehydrogenase",
"metabolites":{
"4mop_c":-1.0,
"__LactoPanGEM__3m1hbtpp_c":1.0,
"__LactoPanGEM__thmpp_c":-1.0,
"co2_c":1.0,
"h_c":-2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10260 or KJMKFHIL_10270",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__OICD",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MOBUDH3",
"name":"3-methyl-2-oxobutanoate dehydrogenase",
"metabolites":{
"3mop_c":-1.0,
"__LactoPanGEM__2mehbtpp_c":1.0,
"__LactoPanGEM__thmpp_c":-1.0,
"co2_c":1.0,
"h_c":-2.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10260 or KJMKFHIL_10270",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOBUDH3",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ZNabc_1",
"name":"Zinc transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__zn_c":1.0,
"__LactoPanGEM__zn_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25940 or KJMKFHIL_25930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ZNabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"PFL",
"name":"pyruvate formate lyase",
"metabolites":{
"accoa_c":1.0,
"coa_c":-1.0,
"for_c":1.0,
"pyr_c":-1.0
},
"lower_bound":0.0,
"upper_bound":2.0,
"gene_reaction_rule":"KJMKFHIL_08480 or KJMKFHIL_08490",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PFL",
"rhea":"RHEA:11844",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLYC3Pabc_1",
"name":"sn-Glycerol 3-phosphate transport via ABC system",
"metabolites":{
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"__LactoPanGEM__atp_c":-1.0,
"glyc3p_c":1.0,
"glyc3p_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02880 or KJMKFHIL_11690 or KJMKFHIL_11680",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLYC3Pabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ALATRS_1",
"name":"Alanyl-tRNA synthetase",
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"__LactoPanGEM__trna_c":-1.0,
"ala__L_c":-1.0,
"amp_c":1.0,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13480",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ALATRS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"LACZ",
"name":"b-galactosidase",
"metabolites":{
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"glc__D_c":1.0,
"h2o_c":-1.0,
"lcts_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LACZ",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BGALS2",
"name":"beta-galactosidase",
"metabolites":{
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"__LactoPanGEM__ga2_hs_c":1.0,
"gal_c":1.0,
"h2o_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BGALS2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HMR_0830",
"name":"D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D- galactosyl-D-glucosylceramide galactohydrolase",
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"__LactoPanGEM__gm2_hs_c":1.0,
"gal_c":1.0,
"h2o_c":-1.0
},
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"upper_bound":1000.0,
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"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMR_0830:2",
"sbo":"SBO:0000176"
}
},
{
"id":"GLUSy",
"name":"glutamate synthase (NADPH)",
"metabolites":{
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"gln__L_c":-1.0,
"glu__L_c":2.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22230 or KJMKFHIL_22220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLUSy",
"rhea":"RHEA:15501",
"sbo":"SBO:0000176"
}
},
{
"id":"Kt1",
"name":"R_potassium_transport_via_voltage_gated_ion_channel",
"metabolites":{
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"k_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25640 or KJMKFHIL_15220 or KJMKFHIL_11020 or KJMKFHIL_05900 or KJMKFHIL_24860 or KJMKFHIL_18900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"Kt1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__RNAS_LBR_1",
"name":"RNA synthesis, L.plantarum specific",
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"__LactoPanGEM__adp_c":0.4,
"__LactoPanGEM__atp_c":-0.710810743235,
"__LactoPanGEM__ctp_c":-0.187747387186,
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},
"lower_bound":0.0,
"upper_bound":1000.0,
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},
"annotation":{
"biggr":"__LactoPanGEM__RNAS_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PROTS_LBR_1",
"name":"protein synthesis_LBR belonging to biomass version 6.0",
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"__LactoPanGEM__alatrna_c":-0.068,
"__LactoPanGEM__argtrna_c":-0.409,
"__LactoPanGEM__asntrna_c":-0.768,
"__LactoPanGEM__asptrna_c":-0.768,
"__LactoPanGEM__atp_c":-0.306,
"__LactoPanGEM__cystrna_c":-0.095,
"__LactoPanGEM__gdp_c":2.0,
"__LactoPanGEM__glntrna_c":-0.714,
"__LactoPanGEM__glutrna_c":-0.275,
"__LactoPanGEM__glytrna_c":-0.1058,
"__LactoPanGEM__gtp_c":-2.0,
"__LactoPanGEM__histrna_c":-0.209,
"__LactoPanGEM__iletrna_c":-0.572,
"__LactoPanGEM__leutrna_c":-0.849,
"__LactoPanGEM__lystrna_c":-0.977,
"__LactoPanGEM__mettrna_c":-0.27,
"__LactoPanGEM__phetrna_c":-0.326,
"__LactoPanGEM__protrna_c":-0.401,
"__LactoPanGEM__sertrna_c":-0.543,
"__LactoPanGEM__thrtrna_c":-0.644,
"__LactoPanGEM__trna_c":9.0498,
"__LactoPanGEM__trptrna_c":-0.07,
"__LactoPanGEM__tyrtrna_c":-0.281,
"__LactoPanGEM__valtrna_c":-0.705,
"h2o_c":-2.306,
"h_c":2.306,
"pi_c":2.306
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PROTS_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DNAS_LBR_1",
"name":"DNA synthesis, LRE specific",
"metabolites":{
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"__LactoPanGEM__adp_c":1.37,
"__LactoPanGEM__atp_c":-1.37,
"__LactoPanGEM__datp_c":-0.310284595735,
"__LactoPanGEM__dctp_c":-0.180906354753,
"__LactoPanGEM__dgtp_c":-0.207484087701,
"__LactoPanGEM__dttp_c":-0.301324961811,
"h2o_c":-1.37,
"h_c":1.37,
"pi_c":1.37,
"ppi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DNAS_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LTA_total",
"name":"Lipteichoic acid reaction (Lb.reuteri specific)",
"metabolites":{
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"__LactoPanGEM__LTAala_LBR_c":-0.765,
"__LactoPanGEM__LTAglc_LBR_c":-0.6,
"__LactoPanGEM__LTAtotal_LBR_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LTA_total",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__LIP_LBR",
"name":"Lipid reaction (Lb. plantarum specific)",
"metabolites":{
"__LactoPanGEM__LIP_LBR_c":1.0,
"__LactoPanGEM__clpn_LBR_c":-0.2,
"__LactoPanGEM__lyspg_LBR_c":-0.23,
"__LactoPanGEM__pg_LBR_c":-0.75
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__LIP_LBR",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PG_ASSEMBLY_1",
"name":"suming up all different kind of pg into one form of pg",
"metabolites":{
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"__LactoPanGEM__pg140_c":-1.0,
"__LactoPanGEM__pg141_c":-1.0,
"__LactoPanGEM__pg160_c":-1.0,
"__LactoPanGEM__pg161_c":-1.0,
"__LactoPanGEM__pg180_c":-1.0,
"__LactoPanGEM__pg181_c":-1.0,
"__LactoPanGEM__pg_LBR_c":7.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PG_ASSEMBLY_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DAG_ASSEMBLY",
"name":"",
"metabolites":{
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"12dgr140_c":-1.0,
"12dgr141_c":-1.0,
"12dgr160_c":-1.0,
"12dgr161_c":-1.0,
"12dgr180_c":-1.0,
"12dgr181_c":-1.0,
"__LactoPanGEM__dag_LBR_c":7.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAG_ASSEMBLY",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PA_ASSEMBLY",
"name":"",
"metabolites":{
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"__LactoPanGEM__agly3p_LBR_c":-1.0,
"__LactoPanGEM__cpocdacp_c":-0.211,
"__LactoPanGEM__ocdcaacp_c":-0.1591,
"__LactoPanGEM__ocdcyaacp_c":-0.3519,
"__LactoPanGEM__octacp_c":-0.75,
"__LactoPanGEM__pa_LBR_c":1.0,
"__LactoPanGEM__palmacp_c":-0.2566,
"__LactoPanGEM__tdeacp_c":-0.687
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PA_ASSEMBLY:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GAT1_LBR_1",
"name":"",
"metabolites":{
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"__LactoPanGEM__agly3p_LBR_c":1.0,
"__LactoPanGEM__cpocdacp_c":-0.211,
"__LactoPanGEM__ocdcaacp_c":-0.1591,
"__LactoPanGEM__ocdcyaacp_c":-0.3519,
"__LactoPanGEM__octacp_c":-0.75,
"__LactoPanGEM__palmacp_c":-0.2566,
"__LactoPanGEM__tdeacp_c":-0.687,
"glyc3p_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GAT1_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"EX___LactoPanGEM__s_c",
"name":"",
"metabolites":{
"__LactoPanGEM__s_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"SINK",
"subsystem":"Intracellular demand",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__s_c",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__apoacp_c",
"name":"",
"metabolites":{
"__LactoPanGEM__apoacp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":-0.0,
"gene_reaction_rule":"DEMAND",
"subsystem":"Intracellular source/sink",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__apoacp_c",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__udcp_c",
"name":"",
"metabolites":{
"__LactoPanGEM__udcp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":-0.0,
"gene_reaction_rule":"DEMAND",
"subsystem":"Intracellular source/sink",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__udcp_c",
"sbo":"SBO:0000627"
}
},
{
"id":"OXAt_1",
"name":"Oxalate secretion by diffusion",
"metabolites":{
"oxa_c":-1.0,
"oxa_e":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"OXAt_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ATPHs_1",
"name":"ATP amine hydrolysis (spontaneous)",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__itp_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ATPHs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__SPIADC_1",
"name":"Indole-3-acetate decarboxylation (Spontaneous Reaction )",
"metabolites":{
"__LactoPanGEM__mdoind_c":1.0,
"co2_c":1.0,
"h_c":-1.0,
"ind3ac_c":-1.0,
"o2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SPIADC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"G5SADs",
"name":"L-glutamate 5-semialdehyde dehydratase (spontaneous)",
"metabolites":{
"glusemald_c":-1.0,
"h2o_c":1.0,
"h_c":1.0,
"pyr5carb_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G5SADs",
"rhea":"RHEA:28234",
"sbo":"SBO:0000176"
}
},
{
"id":"CBMD",
"name":"carbamate deaminase",
"metabolites":{
"cbm_c":-1.0,
"co2_c":1.0,
"h_c":-2.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CBMD",
"rhea":"RHEA:15649",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__SPPD_1",
"name":"Spontaneous Reaction  pyrroline dehydration",
"metabolites":{
"4abutn_c":-1.0,
"__LactoPanGEM__pyrln_c":1.0,
"h2o_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SPPD_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DATPHs_1",
"name":"DATP amine hydrolysis (spontaneous)",
"metabolites":{
"__LactoPanGEM__datp_c":-1.0,
"__LactoPanGEM__ditp_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DATPHs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DHPTDCs_1",
"name":"4,5-dihydroxy-2,3-pentanedione cyclization (spontaneous)",
"metabolites":{
"__LactoPanGEM__hmfurn_c":1.0,
"dhptd_c":-1.0,
"h2o_c":1.0,
"h_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DHPTDCs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FECRMexs_1",
"name":"Ferrichrome Fe(III)-loading reaction (spontaneous)",
"metabolites":{
"__LactoPanGEM__fecrm_c":1.0,
"__LactoPanGEM__fecrm_un_c":-1.0,
"fe3_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FECRMexs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FEOXAMexs_1",
"name":"Ferroxamine Fe3-loading reaction (spontaneous)",
"metabolites":{
"__LactoPanGEM__feoxam_c":1.0,
"__LactoPanGEM__feoxam_un_c":-1.0,
"fe3_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FEOXAMexs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GTPHs_1",
"name":"GTP amine hydrolysis (spontaneous)",
"metabolites":{
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"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0,
"xtp_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GTPHs_1",
"sbo":"SBO:0000176"
}
},
{
"id":"METOX1s",
"name":"methionine oxidation (spontaneous)",
"metabolites":{
"h2o2_c":-1.0,
"h2o_c":1.0,
"met__L_c":-1.0,
"metsox_S__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"METOX1s",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ALACDC_1",
"name":"acetolactate decarboxylation (Spontaneous Reaction )",
"metabolites":{
"alac__S_c:-1":-1.0,
"co2_c":1.0,
"diact_c":1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ALACDC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"AOBUTDs",
"name":"L-2-amino-3-oxobutanoate decarboxylation (spontaneous)",
"metabolites":{
"2aobut_c":-1.0,
"aact_c":1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AOBUTDs",
"rhea":"RHEA:25653",
"sbo":"SBO:0000176"
}
},
{
"id":"AOBUTDs:2",
"name":"L-2-amino-3-oxobutanoate decarboxylation (spontaneous)",
"metabolites":{
"2aobut_c":-1.0,
"aact_c":1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AOBUTDs",
"rhea":"RHEA:25653",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__10M3OUO_1",
"name":"10-methyl-3-oxo-undecanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__10m3uacp_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__10M3OUO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__10MODODACPDH_1",
"name":"10-methyl-3-oxo-dodecanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__mododacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__10MODODACPDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__11M3ODO_1",
"name":"11-methyl-3-oxo-dodecanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__11m3odacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__11M3ODO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__12M3OXOT_1",
"name":"12-methyl-3-oxo-tridecanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__12mdhtacp_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__12M3OXOT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__12M3TDA_1",
"name":"12-methyl-3-oxo-tetra-decanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__12m3htdacp_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__12M3TDA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__12MTDACPTr_1",
"name":"12-methyl-tetra-decanoyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__fa4coa_c":1.0,
"coa_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__12MTDACPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__12MTRDACPTr_1",
"name":"12-methyl-tridecanoyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__fa1coa_c":1.0,
"coa_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
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"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__12MTRDACPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__13DPGG1PPTr_1",
"name":"3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase",
"metabolites":{
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"3pg_c":1.0,
"__LactoPanGEM__g16bp_A_c":1.0,
"g1p_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09000",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__13DPGG1PPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__13M3OTDAO_1",
"name":"13-methyl-3-oxo-tetra-decanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__13m3otdacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__13M3OTDAO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__13MTDACPTr_1",
"name":"13-methyl-tetra-decanoyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__fa3coa_c":1.0,
"coa_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__13MTDACPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__14M3OHO_1",
"name":"14-methyl-3-oxo-hexa-decanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__14m3ohdacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__14M3OHO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__14M3OP_1",
"name":"14-methyl-3-oxo-pentadecanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__14m3opacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__14M3OP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__14MHDACPTr_1",
"name":"14-methyl-hexa-decanoyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__fa12coa_c":1.0,
"coa_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__14MHDACPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__14MPDACPTr_1",
"name":"14-methyl-pentadecanoyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__fa6coa_c":1.0,
"coa_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__14MPDACPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__15M3OHAO_1",
"name":"15-methyl-3-oxo-hexa-decanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
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"__LactoPanGEM__15m3ohdacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
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"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__15M3OHAO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__15NHDACPTr_1",
"name":"15-methyl-hexa-decanoyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
"__LactoPanGEM__15mhdacp_c":-1.0,
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__fa11coa_c":1.0,
"coa_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__15NHDACPTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__2HBO_1",
"name":"2-Hydroxybutyrate:NAD+ Oxidoreductase",
"metabolites":{
"2obut_c":1.0,
"__LactoPanGEM__2hb_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18910 or KJMKFHIL_23250 or KJMKFHIL_18380 or KJMKFHIL_22170 or KJMKFHIL_07330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__2HBO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__2HXICDH_1",
"name":"L-2-hydroxyisocaproate dehydrogenase",
"metabolites":{
"4mop_c":-1.0,
"__LactoPanGEM__2hxic__L_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18910 or KJMKFHIL_04930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__2HXICDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__2MACPT_1",
"name":"2-methylbutanoyl-CoA acyl-carrier-protein transferase",
"metabolites":{
"__LactoPanGEM__2mbcoa_c":-1.0,
"__LactoPanGEM__2mbutacp_c":1.0,
"__LactoPanGEM__acp_c":-1.0,
"coa_c":1.0,
"h_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__2MACPT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__2MPCAC_1",
"name":"2-methylpropionyl-CoA:[acyl-carrier-protein] transferase",
"metabolites":{
"__LactoPanGEM__acp_c":-1.0,
"__LactoPanGEM__isobutacp_c":1.0,
"coa_c":1.0,
"h_c":-1.0,
"ibcoa_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__2MPCAC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"34DHOXPEGOX",
"name":"3,4-Dihydroxyphenylethyleneglycol_NAD+ oxidoreductase",
"metabolites":{
"34dhmald_c":-1.0,
"34dhoxpeg_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"34DHOXPEGOX",
"rhea":"RHEA:31147",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3HAOR_1",
"name":"3-Hydroxyoctodecanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__3hodacp_c":1.0,
"__LactoPanGEM__3oodacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3HAOR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3MBCOT_1",
"name":"3-methylbutanoyl-CoA:[acyl-carrier-protein] transferase",
"metabolites":{
"__LactoPanGEM__acp_c":-1.0,
"__LactoPanGEM__isovacp_c":1.0,
"coa_c":1.0,
"h_c":-1.0,
"ivcoa_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__3MBCOT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4M3OPAO_1",
"name":"4-methyl-3-oxo-pentanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__4m3hpAPC_c":1.0,
"__LactoPanGEM__4m3opacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4M3OPAO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4M3OXHA_1",
"name":"4-methyl-3-oxo-hexanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__4m3hhexacp_c":1.0,
"__LactoPanGEM__4m3ohexacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4M3OXHA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__4OT",
"name":"4 oxalocrotonate tautomerase",
"metabolites":{
"__LactoPanGEM__2hmc_c":-1.0,
"__LactoPanGEM__oxalc_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__4OT:2",
"sbo":"SBO:0000176"
}
},
{
"id":"5DKGR",
"name":"5-keto-D-gluconate 5-reductase",
"metabolites":{
"5dglcn_c":1.0,
"glcn_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13160 or KJMKFHIL_24400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"5DKGR",
"rhea":"RHEA:23940",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__5MET3OH_1",
"name":"5-methyl-3-oxo-hexanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__5m3hacp_c":1.0,
"__LactoPanGEM__5m3hhacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__5MET3OH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__6M3OHAO_1",
"name":"6-methyl-3-oxo-heptanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__6m3hhacp_c":1.0,
"__LactoPanGEM__6m3ohacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__6M3OHAO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__6M3OXO_1",
"name":"6-methyl-3-oxo-octanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__6m3hoacp_c":1.0,
"__LactoPanGEM__6m3oacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__6M3OXO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__7M3ODO_1",
"name":"7-methyl-3-oxo-octanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__7m3hoacp_c":1.0,
"__LactoPanGEM__7me3oxoacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__7M3ODO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__8M3OAO_1",
"name":"8-methyl-3-oxo-decanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__8m3hdacp_c":1.0,
"__LactoPanGEM__8m3odacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__8M3OAO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__8M3ONO_1",
"name":"8-methyl-3-oxo-nonanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__8m3hnacp_c":1.0,
"__LactoPanGEM__8m3oxacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__8M3ONO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__9M3OXPA_1",
"name":"9-methyl-3-oxo-decanoyl-ACP:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__9m3hdacp_c":1.0,
"__LactoPanGEM__9m3odacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__9M3OXPA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT1r",
"name":"acetyl-CoA C-acetyltransferase",
"metabolites":{
"aacoa_c":1.0,
"accoa_c":-2.0,
"coa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT1r",
"rhea":"RHEA:21036",
"sbo":"SBO:0000176"
}
},
{
"id":"ACACT2r",
"name":"acetyl-CoA C-acyltransferase (butanoyl-CoA) (r)",
"metabolites":{
"3ohcoa_c":1.0,
"accoa_c":-1.0,
"btcoa_c":-1.0,
"coa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACACT2r",
"rhea":"RHEA:31111",
"sbo":"SBO:0000176"
}
},
{
"id":"ACODA",
"name":"acetylornithine deacetylase",
"metabolites":{
"ac_c":1.0,
"acorn_c":-1.0,
"h2o_c":-1.0,
"orn__L_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20480",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACODA",
"rhea":"RHEA:15941",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPADPP2:2",
"name":"\ufeffPolyphosphate:ADP phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__pppi_c":-1.0,
"amp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPADPP2",
"sbo":"SBO:0000176"
}
},
{
"id":"APTA1i",
"name":"R_Acetyl_L_L_diaminopimelate_aminotransferase",
"metabolites":{
"26dapime_c":1.0,
"acamoxm_c":-1.0,
"akg_c":1.0,
"glu__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06290 or KJMKFHIL_26420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"APTA1i",
"rhea":"RHEA:25315",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AH6PI_1",
"name":"D-arabino-hex-3-ulose-6-phosphate isomerase",
"metabolites":{
"__LactoPanGEM__ah6p__D_c":-1.0,
"f6p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AH6PI_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AHSERL4_1",
"name":"Cysteine synthase Thiosulfate",
"metabolites":{
"__LactoPanGEM__so3_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"__LactoPanGEM__tsul_c":-1.0,
"ac_c":1.0,
"acser_c":-1.0,
"cys__L_c":1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AHSERL4_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AIRCr_1",
"name":"Phosphoribosylaminoimidazole carboxylase",
"metabolites":{
"__LactoPanGEM__5aizc_c":1.0,
"__LactoPanGEM__air_c":-1.0,
"co2_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02040 or KJMKFHIL_21500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__AIRCr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"AKGt2r",
"name":"_2-oxoglutarate reversible transport via symport",
"metabolites":{
"akg_c":1.0,
"akg_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17550",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AKGt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"AKGt2r:2",
"name":"_2-oxoglutarate reversible transport via symport",
"metabolites":{
"akg_c":1.0,
"akg_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17550",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AKGt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"ALAD_L",
"name":"L-alanine dehydrogenase",
"metabolites":{
"ala__L_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"nh4_c":1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06450",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALAD_L",
"rhea":"RHEA:18405",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ALALAC_1",
"name":"D-alanine-D-lactate ligase (reversible)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__alalac_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"ala__D_c":-1.0,
"lac__D_c":-1.0,
"pi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04950",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ALALAC_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ALCD19y",
"name":"R_alcohol_dehydrogenase__glycerol__NADP_",
"metabolites":{
"glyald_c":-1.0,
"glyc_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALCD19y",
"rhea":"RHEA:23592",
"sbo":"SBO:0000176"
}
},
{
"id":"ALCD19_L",
"name":"R_alcohol_dehydrogenase__L_glyceraldehyde_to_glycerol__NADP_",
"metabolites":{
"Lglyald_c":-1.0,
"glyc_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALCD19_L",
"rhea":"RHEA:38111",
"sbo":"SBO:0000176"
}
},
{
"id":"ALCD23xi",
"name":"R_aldehyde_dehydrogenase__isobutyl_alcohol__NAD_",
"metabolites":{
"2mppal_c":-1.0,
"h_c":-1.0,
"ibutoh_c":1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALCD23xi",
"rhea":"RHEA:64692",
"sbo":"SBO:0000176"
}
},
{
"id":"ALCD2x",
"name":"alcohol dehydrogenase (ethanol)",
"metabolites":{
"acald_c":-1.0,
"etoh_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_13400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALCD2x",
"rhea":"RHEA:25290",
"sbo":"SBO:0000176"
}
},
{
"id":"ALCD3ir",
"name":"alcohol dehydrogenase (propanol)",
"metabolites":{
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"ppal_c":1.0,
"ppoh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ALCD3ir",
"rhea":"RHEA:50704",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ALDD22x_1",
"name":"Aldehyde dehydrogenase 3 aminopropanal NAD",
"metabolites":{
"__LactoPanGEM__aproa_c":-1.0,
"ala_B_c":1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ALDD22x_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ALDDH_1",
"name":"aldehyde dehydrogenase",
"metabolites":{
"1h2nap_c":1.0,
"__LactoPanGEM__hnaphal_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ALDDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ALPAMDH_1",
"name":"alcophosphamide:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__alcopde_c":1.0,
"__LactoPanGEM__aldpham_c":-1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10220",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ALPAMDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"AMPEP13",
"name":"Aminopeptidase",
"metabolites":{
"ala_L_asp__L_c":-1.0,
"ala__L_c":1.0,
"asp__L_c":1.0,
"h2o_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22530 or KJMKFHIL_18270 or KJMKFHIL_22570 or KJMKFHIL_24450 or KJMKFHIL_18260 or KJMKFHIL_00920 or KJMKFHIL_14080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AMPEP13",
"rhea":"RHEA:37267",
"sbo":"SBO:0000176"
}
},
{
"id":"THPAT:2",
"name":"R_Tetrahydrodipicolinate_acetyltransferase",
"metabolites":{
"acamoxm_c":1.0,
"accoa_c":-1.0,
"coa_c":1.0,
"h2o_c":-1.0,
"thdp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THPAT",
"rhea":"RHEA:13085",
"sbo":"SBO:0000176"
}
},
{
"id":"aratyr2",
"name":"aromatic amino acid aminotransferase tyrosine",
"metabolites":{
"34hpp_c":1.0,
"3mop_c":-1.0,
"ile__L_c":1.0,
"tyr__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06290 or KJMKFHIL_26420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"aratyr2",
"sbo":"SBO:0000176"
}
},
{
"id":"aratyr4",
"name":"aromatic amino acid aminotransferase tyrosine",
"metabolites":{
"34hpp_c":1.0,
"indpyr_c":-1.0,
"trp__L_c":1.0,
"tyr__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06290 or KJMKFHIL_26420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"aratyr4",
"sbo":"SBO:0000176"
}
},
{
"id":"ASPR",
"name":"aspartase racemase",
"metabolites":{
"asp__D_c":-1.0,
"asp__L_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23190",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASPR",
"rhea":"RHEA:14973",
"sbo":"SBO:0000176"
}
},
{
"id":"ASPT",
"name":"L-aspartase",
"metabolites":{
"asp__L_c":-1.0,
"fum_c":1.0,
"nh4_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASPT",
"rhea":"RHEA:16601",
"sbo":"SBO:0000176"
}
},
{
"id":"ASPt2r",
"name":"L-aspartate transport in via proton symport",
"metabolites":{
"asp__L_c":1.0,
"asp__L_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_26370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASPt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"TYRTA:2",
"name":"tyrosine transaminase",
"metabolites":{
"34hpp_c":1.0,
"akg_c":-1.0,
"glu__L_c":1.0,
"tyr__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09860 or KJMKFHIL_11930",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TYRTA",
"rhea":"RHEA:15093",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BGLCNADPOX",
"name":"beta-D-Glucose:NADP+ 1-oxoreductase",
"metabolites":{
"g15lac_c":1.0,
"glc__D_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BGLCNADPOX",
"rhea":"RHEA:14405",
"sbo":"SBO:0000176"
}
},
{
"id":"BTNTe",
"name":"Release of biotin across the basolatral membrane",
"metabolites":{
"btn_c":1.0,
"btn_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BTNTe",
"sbo":"SBO:0000655"
}
},
{
"id":"BTS",
"name":"alcohol dehydrogenase (butanol)",
"metabolites":{
"btal_c":-1.0,
"btoh_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BTS",
"rhea":"RHEA:33199",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BUTKr",
"name":"Butyrate kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"but_c":-1.0,
"butpi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BUTKr",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CCPROX_1",
"name":"cis-3-chloro-2-propene-1-ol:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__chylald_c":1.0,
"__LactoPanGEM__cprol_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CCPROX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CDHANT_1",
"name":"\ufeffCadmium, cobalt and zinc/H(+)-K(+) antiporter",
"metabolites":{
"cd2_c":1.0,
"cd2_e":-1.0,
"h_c":-1.0,
"h_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CDHANT_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CDKANT_1",
"name":"\ufeffCadmium, cobalt and zinc/H(+)-K(+) antiporter",
"metabolites":{
"cd2_c":1.0,
"cd2_e":-1.0,
"k_c":-1.0,
"k_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CDKANT_1",
"sbo":"SBO:0000655"
}
},
{
"id":"CHOLD",
"name":"choline dehydrogenase",
"metabolites":{
"betald_c":1.0,
"chol_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CHOLD",
"rhea":"RHEA:33051",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CHOLD2_1",
"name":"Choline dehydrogenase",
"metabolites":{
"betald_c":1.0,
"chol_c":-1.0,
"h_c":1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CHOLD2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"CITt2r",
"name":"R_citrate_reversible_transport_via_symport",
"metabolites":{
"cit_c":1.0,
"cit_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CITt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CLPNS_LBR",
"name":"Cardiolipin Synthase (LRE specific)",
"metabolites":{
"__LactoPanGEM__clpn_LBR_c":1.0,
"__LactoPanGEM__pg_LBR_c":-2.0,
"glyc_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07780 or KJMKFHIL_10070",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CLPNS_LBR",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__COBHANT_1",
"name":"\ufeffCadmium, cobalt and zinc/H(+)-K(+) antiporter",
"metabolites":{
"cobalt2_c":1.0,
"cobalt2_e":-1.0,
"h_c":-1.0,
"h_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__COBHANT_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__COBKANT_1",
"name":"\ufeffCadmium, cobalt and zinc/H(+)-K(+) antiporter",
"metabolites":{
"cobalt2_c":1.0,
"cobalt2_e":-1.0,
"k_c":-1.0,
"k_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__COBKANT_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CPEND_1",
"name":"\ufeffCyclopentanol dehydrogenase",
"metabolites":{
"__LactoPanGEM__cpol_c":-1.0,
"__LactoPanGEM__cpon_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CPEND_1",
"sbo":"SBO:0000176"
}
},
{
"id":"CYS",
"name":"L-cysteine",
"metabolites":{
"cys__L_c":1.0,
"h2o_c":1.0,
"h2s_c":-1.0,
"h_c":-1.0,
"ser__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CYS",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CYSDSF",
"name":"Cysteine desulfurase",
"metabolites":{
"__LactoPanGEM__s_c":1.0,
"ala__L_c":1.0,
"cys__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07930 or KJMKFHIL_10620 or KJMKFHIL_07530",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYSDSF",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CYTDK1_1",
"name":"ATPcytidine 5-Phosphotransferase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"cmp_c":1.0,
"cytd_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYTDK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CYTDK2_1",
"name":"cytidine kinase (GTP)",
"metabolites":{
"__LactoPanGEM__gdp_c":1.0,
"__LactoPanGEM__gtp_c":-1.0,
"cmp_c":1.0,
"cytd_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYTDK2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DADA",
"name":"Deoxyadenosine deaminase",
"metabolites":{
"dad_2_c":-1.0,
"din_c":1.0,
"h2o_c":-1.0,
"h_c":-1.0,
"nh4_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06750",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DADA",
"rhea":"RHEA:28190",
"sbo":"SBO:0000176"
}
},
{
"id":"DALAt2r",
"name":"D-alanine transport via proton symport",
"metabolites":{
"ala__D_c":1.0,
"ala__D_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DALAt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"DDPGA",
"name":"2-dehydro-3-deoxy-phosphogluconate aldolase",
"metabolites":{
"4h2oglt_c":-1.0,
"glx_c":1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05740 or KJMKFHIL_23920",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DDPGA",
"rhea":"RHEA:18169",
"sbo":"SBO:0000176"
}
},
{
"id":"DGC3D",
"name":"R04049",
"metabolites":{
"2dglcn_c":-1.0,
"3ddgc_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12500 or KJMKFHIL_23910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DGC3D",
"rhea":"RHEA:12160",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DHFOR2_1",
"name":"dihydrofolate reductase",
"metabolites":{
"__LactoPanGEM__fol_c":1.0,
"dhf_c":-1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08760",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DHFOR2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DHNAOT4",
"name":"1,4-dihydroxy-2-naphthoate octaprenyltransferase",
"metabolites":{
"2dmmql8_c":1.0,
"co2_c":1.0,
"dhna_c":-1.0,
"h_c":-1.0,
"octdp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06360 or KJMKFHIL_15870 or KJMKFHIL_15880",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHNAOT4",
"rhea":"RHEA:30099",
"sbo":"SBO:0000176"
}
},
{
"id":"DHORD_NAD",
"name":"dihydoorotic acid dehydrogenase NAD",
"metabolites":{
"dhor__S_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"orot_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10200",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHORD_NAD",
"rhea":"RHEA:13513",
"sbo":"SBO:0000176"
}
},
{
"id":"DHPR",
"name":"_6,7-dihydropteridine reductase",
"metabolites":{
"dhbpt_c":-1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0,
"thbpt_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08360",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHPR",
"sbo":"SBO:0000176"
}
},
{
"id":"BKDC",
"name":"2-methylpropanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase",
"metabolites":{
"2mpdhl_c":-1.0,
"coa_c":-1.0,
"dhlam_c":1.0,
"ibcoa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BKDC",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DHRT_ivcoa_1",
"name":"3-methylbutanoyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-(3-methylbutanoyl)transferase",
"metabolites":{
"__LactoPanGEM__3mbdhl_c":-1.0,
"coa_c":-1.0,
"dhlam_c":1.0,
"ivcoa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10280 or KJMKFHIL_07350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DHRT_ivcoa_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DKGLCNR1_1",
"name":"2,5-diketo-D-gluconate reductase",
"metabolites":{
"2ddglcn_c":1.0,
"__LactoPanGEM__46dh25dohxn_c":-1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12500 or KJMKFHIL_13270 or KJMKFHIL_25800 or KJMKFHIL_23910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DKGLCNR1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DKI",
"name":"5 Dehydro 4 deoxy D glucuronate ketol isomerase",
"metabolites":{
"__LactoPanGEM__46dh25dohxn_c":1.0,
"__LactoPanGEM__5dh4dglcn_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23900",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DKI",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DRPA_1",
"name":"deoxyribose-phosphate aldolase",
"metabolites":{
"__LactoPanGEM__rbt5p_c":-1.0,
"acald_c":1.0,
"g3p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24630 or KJMKFHIL_25720",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DRPA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"DSERt2",
"name":"D-serine transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"ser__D_c":1.0,
"ser__D_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DSERt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ERPHL",
"name":"3-Phospho-D-erythronate hydro-lyase",
"metabolites":{
"__LactoPanGEM__3pen_c":-1.0,
"__LactoPanGEM__poldtetru_c":1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03080 or KJMKFHIL_21030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ERPHL:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FAS1_6_c_1",
"name":"[Acyl-carrier-protein] acetyltransferase",
"metabolites":{
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__tdeacp_c":-1.0,
"coa_c":-1.0,
"h_c":1.0,
"tdcoa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FAS1_6_c_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FAS1_7_c_1",
"name":"[Acyl-carrier-protein] acetyltransferase",
"metabolites":{
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__hedacp_c":-1.0,
"coa_c":-1.0,
"h_c":1.0,
"pmtcoa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FAS1_7_c_1",
"sbo":"SBO:0000176"
}
},
{
"id":"FBA3",
"name":"Sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase",
"metabolites":{
"dhap_c":1.0,
"e4p_c":1.0,
"s17bp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25460 or KJMKFHIL_17160 or KJMKFHIL_11840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FBA3",
"rhea":"RHEA:30167",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FBA4_1",
"name":"D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase",
"metabolites":{
"__LactoPanGEM__xu1p__L_c":-1.0,
"dhap_c":1.0,
"gcald_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04640",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FBA4_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FCLT_1",
"name":"Heme B synthesis reaction",
"metabolites":{
"__LactoPanGEM__fe_c":-1.0,
"h_c":2.0,
"pheme_c":1.0,
"ppp9_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24820",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FCLT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FE2Tr_1",
"name":"\ufeffFe(2+) transporter FeoB",
"metabolites":{
"fe3_c":1.0,
"fe3_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02690 or KJMKFHIL_27330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FE2Tr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__FNOR_1_1",
"name":"Ferredoxin:NADPH oxidoreductase",
"metabolites":{
"__LactoPanGEM__fdxox_c":2.0,
"__LactoPanGEM__fdxrd_c":-2.0,
"h_c":-1.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FNOR_1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FORMDHPOX_1",
"name":"5-(2'-Formylethyl)-4,6-dihydroxypicolinate oxidoreductase (NADH)",
"metabolites":{
"__LactoPanGEM__cetdhpic_c":1.0,
"__LactoPanGEM__fetdhpic_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FORMDHPOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FORMDHPOX2_1",
"name":"5-(2'-Formylethyl)-4,6-dihydroxypicolinate oxidoreductase (NADPH)",
"metabolites":{
"__LactoPanGEM__cetdhpic_c":1.0,
"__LactoPanGEM__fetdhpic_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nadp_c":-1.0,
"nadph_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FORMDHPOX2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"FRDx",
"name":"fumarate reductase NADH",
"metabolites":{
"fum_c":-1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0,
"succ_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25410",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FRDx",
"rhea":"RHEA:18281",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FRXOXR_1",
"name":"[2Fe-2S]-ferredoxin:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__fdxox_c":2.0,
"__LactoPanGEM__fdxrd_c":-2.0,
"h_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FRXOXR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FTHFLi_1",
"name":"Formate-tetrahydrofolate ligase",
"metabolites":{
"10fthf_c":1.0,
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"for_c":-1.0,
"pi_c":1.0,
"thf_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10110",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FTHFLi_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FTr_1",
"name":"Fluoride transport via transpoeter",
"metabolites":{
"f_c":-1.0,
"f_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21070 or KJMKFHIL_21060",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FTr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"G1Dx",
"name":"R_glucose_1_dehydrogenase__NAD_",
"metabolites":{
"g15lac_c":1.0,
"glc__D_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G1Dx",
"rhea":"RHEA:14293",
"sbo":"SBO:0000176"
}
},
{
"id":"G3PD1ir",
"name":"glycerol-3-phosphate dehydrogenase (NAD)",
"metabolites":{
"dhap_c":1.0,
"glyc3p_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"G3PD1ir",
"rhea":"RHEA:11092",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__G6PI_1",
"name":"Glucose 6 phosphate isomerase",
"metabolites":{
"M01389_c":1.0,
"__LactoPanGEM__g6p_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__G6PI_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGI_1:2",
"name":"Glucose-6-Phosphate Isomerase",
"metabolites":{
"__LactoPanGEM__g6p_c":-1.0,
"f6p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGI_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GALUi:2",
"name":"UTP-glucose-1-phosphate uridylyltransferase (irreversible)",
"metabolites":{
"__LactoPanGEM__utp_c":-1.0,
"g1p_c":-1.0,
"h_c":-1.0,
"ppi_c":1.0,
"udpg_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GALUi",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GCCc",
"name":"glycine-cleavage complex",
"metabolites":{
"__LactoPanGEM__dhlpro_c":-1.0,
"__LactoPanGEM__lpro_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07350 or KJMKFHIL_10700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GCCc",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GK2_1",
"name":"guanylate kinase (GMPdATP)",
"metabolites":{
"__LactoPanGEM__dadp_c":1.0,
"__LactoPanGEM__datp_c":-1.0,
"__LactoPanGEM__gdp_c":1.0,
"gmp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17870 or KJMKFHIL_00780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GK2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"GALM1",
"name":"Conversion of CHEBI:15903 to CHEBI:4167, because one is an instance of the other.",
"metabolites":{
"glc__D_c":-1.0,
"glc__bD_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15430",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GALM1",
"sbo":"SBO:0000176"
}
},
{
"id":"GLCNt2r",
"name":"D-gluconate transport via proton symport, reversible",
"metabolites":{
"glcn_c":1.0,
"glcn_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLCNt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"GLUDxi",
"name":"glutamate dehydrogenase (NAD)",
"metabolites":{
"akg_c":1.0,
"glu__L_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"nh4_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23240",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLUDxi",
"rhea":"RHEA:15133",
"sbo":"SBO:0000176"
}
},
{
"id":"GLXO1",
"name":"glyoxylate oxidase",
"metabolites":{
"glx_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"nad_c":-1.0,
"nadh_c":1.0,
"oxa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLXO1",
"sbo":"SBO:0000176"
}
},
{
"id":"GLYCLTDx",
"name":"Glycolate dehydrogenase (NAD)",
"metabolites":{
"glx_c":-1.0,
"glyclt_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22920",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLYCLTDx",
"rhea":"RHEA:18229",
"sbo":"SBO:0000176"
}
},
{
"id":"GLYCt",
"name":"glycerol transport via channel",
"metabolites":{
"glyc_c":-1.0,
"glyc_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15510 or KJMKFHIL_13650",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLYCt",
"sbo":"SBO:0000655"
}
},
{
"id":"GLYt2r",
"name":"glycine reversible transport via proton symport",
"metabolites":{
"gly_c":1.0,
"gly_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14570",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GLYt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"GDR",
"name":"glutathione amide:NAD+ oxidoreductase",
"metabolites":{
"gthox_c":1.0,
"gthrd_c":-2.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06500",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GDR",
"rhea":"RHEA:75699",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HBUR1_1",
"name":"(3R)-3-Hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__3hbutacp_c":1.0,
"__LactoPanGEM__actacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12130 or KJMKFHIL_13160 or KJMKFHIL_24400 or KJMKFHIL_13000 or KJMKFHIL_03590",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HBUR1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HCLTr_1",
"name":"\ufeffH(+)/Cl(-) exchange transporter",
"metabolites":{
"cl_c":1.0,
"cl_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03050",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HCLTr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"HISTD",
"name":"histidinol dehydrogenase",
"metabolites":{
"h2o_c":-1.0,
"h_c":3.0,
"his__L_c":1.0,
"histd_c":-1.0,
"nad_c":-2.0,
"nadh_c":2.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HISTD",
"rhea":"RHEA:20641",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HISTDb_1_1",
"name":"Histidinal dehydrogenase",
"metabolites":{
"__LactoPanGEM__histl__L_c":-1.0,
"h2o_c":-1.0,
"h_c":2.0,
"his__L_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HISTDb_1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HISTDDH_1",
"name":"L-Histidinol:NAD+ oxidoreductase_c0",
"metabolites":{
"__LactoPanGEM__histl__L_c":1.0,
"h_c":1.0,
"histd_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08280",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HISTDDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HLU6PS_1",
"name":"3-hexulose-6-phosphate synthase",
"metabolites":{
"__LactoPanGEM__ah6p__D_c":1.0,
"fald_c":-1.0,
"ru5p__D_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17640",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HLU6PS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HMANORD",
"name":"(S)-4-hydroxymandelate:oxygen 1-oxidoreductase",
"metabolites":{
"__LactoPanGEM__4hma_c":1.0,
"__LactoPanGEM__4shma_c":-1.0,
"h2o2_c":1.0,
"o2_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14960 or KJMKFHIL_18380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMANORD",
"sbo":"SBO:0000176"
}
},
{
"id":"HMGCOAS",
"name":"Hydroxymethylglutaryl CoA synthase (ir)",
"metabolites":{
"aacoa_c":1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"h2o_c":1.0,
"h_c":-1.0,
"hmgcoa_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HMGCOAS",
"rhea":"RHEA:10188",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HMNOX_1",
"name":"1-hydroxymethylnaphthalene:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__naphal1_c":1.0,
"__LactoPanGEM__naphmeth_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HMNOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__HPTOZNDH_1",
"name":"4-hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__hphtetox_c":-1.0,
"__LactoPanGEM__phoxdi_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HPTOZNDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"HPYRRx",
"name":"Hydroxypyruvate reductase (NADH)",
"metabolites":{
"glyc__R_c":1.0,
"h_c":-1.0,
"hpyr_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22920 or KJMKFHIL_09970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HPYRRx",
"rhea":"RHEA:17905",
"sbo":"SBO:0000176"
}
},
{
"id":"HSDxi",
"name":"R_homoserine_dehydrogenase__NADH___irreversible",
"metabolites":{
"aspsa_c":-1.0,
"h_c":-1.0,
"hom__L_c":1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06230",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HSDxi",
"rhea":"RHEA:15757",
"sbo":"SBO:0000176"
}
},
{
"id":"HSTPT",
"name":"histidinol-phosphate transaminase",
"metabolites":{
"akg_c":1.0,
"glu__L_c":-1.0,
"hisp_c":1.0,
"imacp_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08350 or KJMKFHIL_10350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HSTPT",
"rhea":"RHEA:23744",
"sbo":"SBO:0000176"
}
},
{
"id":"ILEt2r",
"name":"L-isoleucine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"ile__L_c":1.0,
"ile__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ILEt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"IMPD",
"name":"IMP dehydrogenase",
"metabolites":{
"h2o_c":-1.0,
"h_c":1.0,
"imp_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"xmp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13440 or KJMKFHIL_23120",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"IMPD",
"rhea":"RHEA:11708",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__IMZ5ACHL",
"name":"4-Imidazolone-5-acetate hydro lyase",
"metabolites":{
"__LactoPanGEM__imiac_c":1.0,
"__LactoPanGEM__nfminasp_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15990",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__IMZ5ACHL:2",
"sbo":"SBO:0000176"
}
},
{
"id":"INS2D",
"name":"R_inositol_2_dehydrogenase",
"metabolites":{
"2ins_c":1.0,
"h_c":1.0,
"inost_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15630",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"INS2D:2",
"sbo":"SBO:0000176"
}
},
{
"id":"INSTt2",
"name":"inositol transport in via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"inost_c":1.0,
"inost_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02070",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"INSTt2",
"sbo":"SBO:0000655"
}
},
{
"id":"Kt3r",
"name":"R_potassium_transport_out_via_proton_antiport",
"metabolites":{
"h_c":-1.0,
"h_e":1.0,
"k_c":1.0,
"k_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02750 or KJMKFHIL_25080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"Kt3r",
"sbo":"SBO:0000655"
}
},
{
"id":"Kt3r:2",
"name":"R_potassium_transport_out_via_proton_antiport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"k_c":-1.0,
"k_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02750 or KJMKFHIL_25080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"Kt3r",
"sbo":"SBO:0000655"
}
},
{
"id":"LCADi:2",
"name":"lactaldehyde dehydrogenase",
"metabolites":{
"h2o_c":-1.0,
"h_c":2.0,
"lac__L_c":1.0,
"lald__L_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21190",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LCADi",
"rhea":"RHEA:14277",
"sbo":"SBO:0000176"
}
},
{
"id":"LEUt2r",
"name":"L-leucine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"leu__L_c":1.0,
"leu__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LEUt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"LEUTAi",
"name":"leucine transaminase (irreversible)",
"metabolites":{
"4mop_c":1.0,
"akg_c":-1.0,
"glu__L_c":1.0,
"leu__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17740",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LEUTAi",
"rhea":"RHEA:18321",
"sbo":"SBO:0000176"
}
},
{
"id":"MACCOAT",
"name":"R_acetyl_CoA_C_acyltransferase__2_Methyl_3_acetoacetyl_CoA_",
"metabolites":{
"2maacoa_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"ppcoa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MACCOAT",
"rhea":"RHEA:30719",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MACPMT_1",
"name":"Malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase",
"metabolites":{
"__LactoPanGEM__acp_c":-1.0,
"__LactoPanGEM__malacp_c":1.0,
"coa_c":1.0,
"h_c":-1.0,
"malcoa_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MACPMT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MALCOAPYRCTr_1",
"name":"Malonyl-CoA:pyruvate carboxytransferase",
"metabolites":{
"accoa_c":1.0,
"malcoa_c":-1.0,
"oaa_c":1.0,
"pyr_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10160",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MALCOAPYRCTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"MCLORi",
"name":"_3-Mercaptolactate:NAD+ oxidoreductase",
"metabolites":{
"h_c":-1.0,
"mercplac_c":1.0,
"mercppyr_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_22170 or KJMKFHIL_23250 or KJMKFHIL_07330 or KJMKFHIL_18380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MCLORi",
"sbo":"SBO:0000176"
}
},
{
"id":"MELIBt2",
"name":"melibiose transport in via symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"melib_c":1.0,
"melib_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02640",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MELIBt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__METHOX_1",
"name":"(2-naphthyl)methanol:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__2nlmeth_c":-1.0,
"__LactoPanGEM__naphal2_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__METHOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MGt5",
"name":"magnesium transport in/out via permease (no H+)",
"metabolites":{
"__LactoPanGEM__mg_c":-1.0,
"__LactoPanGEM__mg_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14760 or KJMKFHIL_03660 or KJMKFHIL_05890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MGt5",
"sbo":"SBO:0000655"
}
},
{
"id":"MHPGLUT",
"name":"5 methyltetrahydropteroyltriglutamate homocysteine S methyltransferase",
"metabolites":{
"hcys__L_c":-1.0,
"hpglu_c":1.0,
"met__L_c":1.0,
"mhpglu_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MHPGLUT",
"rhea":"RHEA:21196",
"sbo":"SBO:0000176"
}
},
{
"id":"MNt2",
"name":"manganese transport in via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"mn2_c":1.0,
"mn2_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_24830 or KJMKFHIL_21300 or KJMKFHIL_05860",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MNt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__MOSDC",
"name":"methyloxaloacetate carboxy-lyase (2-oxobutanoate-forming)",
"metabolites":{
"2obut_c":1.0,
"__LactoPanGEM__2m3osuc_c":-1.0,
"co2_c":1.0,
"h_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOSDC",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MTHFR2",
"name":"5,10-methylenetetrahydrofolate reductase (NADH)",
"metabolites":{
"__LactoPanGEM__5mthf_c":1.0,
"h_c":-2.0,
"mlthf_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_23350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MTHFR2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NADHXD_1",
"name":"NADHX dehydratase",
"metabolites":{
"__LactoPanGEM__adp_c":-1.0,
"amp_c":1.0,
"h_c":1.0,
"nadh_c":1.0,
"nadhx__S_c":-1.0,
"pi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_04380",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NADHXD_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NADK5_1",
"name":"NAD kinase (dTTP)",
"metabolites":{
"__LactoPanGEM__dtdp_c":1.0,
"__LactoPanGEM__dttp_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_03750",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NADK5_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NAt3_1",
"name":"sodium transport out via proton antiport",
"metabolites":{
"__LactoPanGEM__na_c":-1.0,
"__LactoPanGEM__na_e":1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02750 or KJMKFHIL_25080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NAt3_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__NDPK9",
"name":"Nucleoside-Diphosphate Kinase (ATP:IDP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__idp_c":-1.0,
"__LactoPanGEM__itp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NDPK9",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NFASPAMH_1",
"name":"N-Formyl-L-aspartate amidohydrolase",
"metabolites":{
"__LactoPanGEM__nforasp_c":-1.0,
"asp__L_c":1.0,
"for_c":1.0,
"h2o_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07390",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__NFASPAMH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"NH4t",
"name":"ammonia reversible transport",
"metabolites":{
"nh4_c":1.0,
"nh4_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NH4t",
"sbo":"SBO:0000655"
}
},
{
"id":"NH4t:2",
"name":"ammonia reversible transport",
"metabolites":{
"nh4_c":1.0,
"nh4_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"NH4t",
"sbo":"SBO:0000655"
}
},
{
"id":"P5CR",
"name":"pyrroline-5-carboxylate reductase",
"metabolites":{
"h_c":-2.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"pro__L_c":1.0,
"pyr5carb_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02550",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"P5CR",
"rhea":"RHEA:14109",
"sbo":"SBO:0000176"
}
},
{
"id":"P5CRx",
"name":"pyrroline-5-carboxylate reductase(nadh)",
"metabolites":{
"h_c":-2.0,
"nad_c":1.0,
"nadh_c":-1.0,
"pro__L_c":1.0,
"pyr5carb_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02550",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"P5CRx",
"rhea":"RHEA:14105",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PAPPT2_1",
"name":"phospho-N-acetylmuramoyl-pentapeptide-transferase (gamma-glutamate)",
"metabolites":{
"__LactoPanGEM__uGgla_c":-1.0,
"__LactoPanGEM__uaGgla_c":1.0,
"udcpp_c":-1.0,
"ump_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07720",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PAPPT2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PDHbr_1",
"name":"acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase",
"metabolites":{
"__LactoPanGEM__adhlam_c":-1.0,
"accoa_c":1.0,
"coa_c":-1.0,
"dhlam_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07350",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PDHbr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PDHcr",
"name":"Pyruvate dehydrogenase (dihydrolipoamide dehydrogenase) reversible",
"metabolites":{
"dhlam_c":-1.0,
"h_c":1.0,
"lpam_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06500 or KJMKFHIL_10250 or KJMKFHIL_07340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PDHcr",
"rhea":"RHEA:33059",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PEPGLCSS_1",
"name":"Peptidoglycan subunit synthesis",
"metabolites":{
"__LactoPanGEM__pgsub_1_c":-1.0,
"__LactoPanGEM__pgsub_c":1.0,
"__LactoPanGEM__udcpdp_c":1.0,
"h_c":1.0,
"uaagmda_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01750 or KJMKFHIL_13740 or KJMKFHIL_09910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PEPGLCSS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGMT_1:2",
"name":"Phosphoglucomutase",
"metabolites":{
"__LactoPanGEM__g6p_c":-1.0,
"g1p_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGMT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PGMT_1:3",
"name":"Phosphoglucomutase",
"metabolites":{
"__LactoPanGEM__g6p_c":1.0,
"g1p_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PGMT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PNTOte",
"name":"Transport of (R)-Pantothenate",
"metabolites":{
"pnto__R_c":1.0,
"pnto__R_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02400",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PNTOte",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__PPK2r_1",
"name":"polyphosphate kinase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__pppi_c":1.0,
"ppi_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18810",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPK2r_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PPOLMCDH_1",
"name":"2-phenyl-1,3-propanediol monocarbamate:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__cylphpal_c":1.0,
"__LactoPanGEM__phpromc_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPOLMCDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PRAIi",
"name":"phosphoribosylanthranilate isomerase (irreversible)",
"metabolites":{
"2cpr5p_c":1.0,
"pran_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PRAIi",
"rhea":"RHEA:21540",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__PRIBGLYNFTr_1",
"name":"phosphoribosylglycinamide formyltransferase 1",
"metabolites":{
"fgam_c":1.0,
"gar_c":-1.0,
"h_c":2.0,
"methf_c":-1.0,
"thf_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01970",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PRIBGLYNFTr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"PTRCORNt7",
"name":"putrescine/ornithine antiporter",
"metabolites":{
"orn__L_c":-1.0,
"orn__L_e":1.0,
"ptrc_c":1.0,
"ptrc_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25780 or KJMKFHIL_26370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PTRCORNt7",
"sbo":"SBO:0000655"
}
},
{
"id":"PTRCt2",
"name":"putrescine transport in via proton symport, reversible",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"ptrc_c":1.0,
"ptrc_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25780 or KJMKFHIL_26370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PTRCt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__r0620",
"name":"R03316",
"metabolites":{
"__LactoPanGEM__chppythpp_c":-1.0,
"__LactoPanGEM__sdhlam_c":1.0,
"__LactoPanGEM__thmpp_c":1.0,
"lpam_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06500 or KJMKFHIL_10250 or KJMKFHIL_07340",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__r0620:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__r0739_1",
"name":"R04805",
"metabolites":{
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"xol7ah2al_c":1.0,
"xol7ah3_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__r0739_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__r0775_1",
"name":"formamidopyrimidine nucleoside triphosphate amidohydrolase",
"metabolites":{
"__LactoPanGEM__dampyrnuc3p_c":1.0,
"__LactoPanGEM__fopynuc3p_c":-1.0,
"for_c":1.0,
"h2o_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__r0775_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__r0777",
"name":"2,5-Diaminopyrimidine nucleoside triphosphate mutase",
"metabolites":{
"__LactoPanGEM__dampyrnuc3p_c":-1.0,
"__LactoPanGEM__diamoxopyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_09730",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__r0777:2",
"sbo":"SBO:0000176"
}
},
{
"id":"RDH1",
"name":"retinol dehydrogenase (all-trans)",
"metabolites":{
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"retinal_c":1.0,
"retinol_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RDH1",
"rhea":"RHEA:21284",
"sbo":"SBO:0000176"
}
},
{
"id":"RIBFLVt2",
"name":"R_riboflavin_transport_in_via_proton_symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"ribflv_c":1.0,
"ribflv_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12590 or KJMKFHIL_23720 or KJMKFHIL_04450 or KJMKFHIL_07590 or KJMKFHIL_06510 or KJMKFHIL_21270 or KJMKFHIL_11880 or KJMKFHIL_08910 or KJMKFHIL_14230 or KJMKFHIL_25310 or KJMKFHIL_06980",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"RIBFLVt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__RNTR1",
"name":"ribonucleoside-triphosphate reductase (ATP)",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__datp_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01920 or KJMKFHIL_05060 or KJMKFHIL_15940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNTR1:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RNTR2",
"name":"ribonucleoside-triphosphate reductase (GTP)",
"metabolites":{
"__LactoPanGEM__dgtp_c":1.0,
"__LactoPanGEM__gtp_c":-1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01920 or KJMKFHIL_05060 or KJMKFHIL_15940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNTR2:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RNTR3",
"name":"ribonucleoside-triphosphate reductase (CTP)",
"metabolites":{
"__LactoPanGEM__ctp_c":-1.0,
"__LactoPanGEM__dctp_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01920 or KJMKFHIL_05060 or KJMKFHIL_15940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNTR3:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RNTR4",
"name":"ribonucleoside-triphosphate reductase (UTP)",
"metabolites":{
"__LactoPanGEM__dutp_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"__LactoPanGEM__utp_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01920 or KJMKFHIL_05060 or KJMKFHIL_15940",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNTR4:2",
"sbo":"SBO:0000176"
}
},
{
"id":"SBTD_D2",
"name":"D-sorbitol dehydrogenase (R)",
"metabolites":{
"fru_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"sbt__D_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SBTD_D2",
"sbo":"SBO:0000176"
}
},
{
"id":"SHSL2",
"name":"R_O_succinylhomoserine_lyase__H2S_",
"metabolites":{
"h2s_c":-1.0,
"hcys__L_c":1.0,
"succ_c":1.0,
"suchms_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27050",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SHSL2",
"rhea":"RHEA:27826",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__STCOATr_1",
"name":"stearyl-ACP:[acyl-carrier-protein] transferase",
"metabolites":{
"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__octacp_c":-1.0,
"coa_c":-1.0,
"h_c":1.0,
"stcoa_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_13010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__STCOATr_1",
"sbo":"SBO:0000176"
}
},
{
"id":"TRSARyr",
"name":"Tartronate semialdehyde reductase (NADP)",
"metabolites":{
"2h3opp_c":-1.0,
"glyc__R_c":1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TRSARyr",
"rhea":"RHEA:18841",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TCHPOX_1",
"name":"trans-3-Chloro-2-propene-1-ol:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__challyal_c":1.0,
"__LactoPanGEM__cpd04015_c":-1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_14890 or KJMKFHIL_13400 or KJMKFHIL_11490 or KJMKFHIL_01420",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TCHPOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TCLETHOX_1",
"name":"trichloroethanol:NAD+ oxidoreductase",
"metabolites":{
"__LactoPanGEM__chhyd_c":-1.0,
"__LactoPanGEM__tcheth_c":1.0,
"h2o_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TCLETHOX_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__THBPOX",
"name":"5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase",
"metabolites":{
"dhbpt_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0,
"thbpt_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08360",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__THBPOX",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__THRCLAS_1",
"name":"L-threonylcarbamoyladenylate synthase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__thrcad_c":1.0,
"h2co3_c":-1.0,
"h2o_c":1.0,
"ppi_c":1.0,
"thr__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10870",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__THRCLAS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"THRD",
"name":"L-threonine dehydrogenase",
"metabolites":{
"2aobut_c":1.0,
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"thr__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_06890 or KJMKFHIL_11490",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THRD",
"rhea":"RHEA:13161",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__TSULR3e_1",
"name":"Thiosulfate Reductase",
"metabolites":{
"__LactoPanGEM__so3_c":1.0,
"__LactoPanGEM__tsul_c":-1.0,
"gthox_c":1.0,
"gthrd_c":-2.0,
"h2s_c":1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01060",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__TSULR3e_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAG2EMA_1",
"name":"UDP-N-acetyl-D-glucosamine 2-epimerase (Hydrolysis)",
"metabolites":{
"__LactoPanGEM__udp_c":1.0,
"acmana_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"uacgam_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18010",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAG2EMA_1",
"sbo":"SBO:0000176"
}
},
{
"id":"UAG4Ei",
"name":"UDP-N-acetylglucosamine 4-epimerase",
"metabolites":{
"uacgam_c":-1.0,
"udpacgal_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17960 or KJMKFHIL_15460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UAG4Ei",
"rhea":"RHEA:20517",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UAGPT3_1",
"name":"UDP-N-acetyl-D-glucosamine:undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine 4-beta-N-acetylglucosaminlytransferase",
"metabolites":{
"__LactoPanGEM__udp_c":1.0,
"h_c":1.0,
"uaagmda_c":1.0,
"uacgam_c":-1.0,
"uagmda_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_07700",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UAGPT3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UDG4EP_1",
"name":"UDPglucose 4-epimerase",
"metabolites":{
"__LactoPanGEM__dtdpgal_c":1.0,
"dtdpglu_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17960 or KJMKFHIL_15460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UDG4EP_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UDPADGLUCE",
"name":"UDP-GlcNAcA 4-epimerase",
"metabolites":{
"__LactoPanGEM__udpacgalu_c":1.0,
"__LactoPanGEM__udpadgluc_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UDPADGLUCE",
"sbo":"SBO:0000176"
}
},
{
"id":"UDPGALM",
"name":"UDPgalactopyranose mutase",
"metabolites":{
"udpgal_c":-1.0,
"udpgalfur_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12440",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UDPGALM",
"rhea":"RHEA:24132",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__URAHL_1",
"name":"uracil hydro-lyase (adding D-ribose 5-phosphate;pseudouridine-5'-phosphate-forming)",
"metabolites":{
"__LactoPanGEM__psuri5p_c":1.0,
"h2o_c":1.0,
"r5p_c":-1.0,
"ura_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_00180 or KJMKFHIL_19910",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__URAHL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"URAt2",
"name":"uracil transport in via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"ura_c":1.0,
"ura_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10150",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"URAt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__URED_1",
"name":"urocanate reductase",
"metabolites":{
"__LactoPanGEM__dhurcan_c":-1.0,
"__LactoPanGEM__urcan_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25410",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__URED_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__URIK1_1",
"name":"Uridine Kinase (ATP:Uridine)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h_c":1.0,
"ump_c":1.0,
"uri_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__URIK1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__URIK2_1",
"name":"uridine kinase (GTP:Uridine)",
"metabolites":{
"__LactoPanGEM__gdp_c":1.0,
"__LactoPanGEM__gtp_c":-1.0,
"h_c":1.0,
"ump_c":1.0,
"uri_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__URIK2_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__URIK3_1",
"name":"Urik3",
"metabolites":{
"__LactoPanGEM__idp_c":1.0,
"__LactoPanGEM__itp_c":-1.0,
"h_c":1.0,
"ump_c":1.0,
"uri_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__URIK3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__UTCY_1",
"name":"UTP:cytidine 5'-phosphotransferase",
"metabolites":{
"__LactoPanGEM__udp_c":1.0,
"__LactoPanGEM__utp_c":-1.0,
"cmp_c":1.0,
"cytd_c":-1.0,
"h_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_01170",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__UTCY_1",
"sbo":"SBO:0000176"
}
},
{
"id":"VALt2r",
"name":"L-valine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"val__L_c":1.0,
"val__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_27090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"VALt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"X5PL3E",
"name":"L-xylulose 5-phosphate 3-epimerase",
"metabolites":{
"ru5p__L_c":1.0,
"xu5p__L_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12100",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"X5PL3E",
"rhea":"RHEA:18497",
"sbo":"SBO:0000176"
}
},
{
"id":"XANt2",
"name":"xanthine transport in via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"xan_c":1.0,
"xan_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_21490",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"XANt2",
"sbo":"SBO:0000655"
}
},
{
"id":"XYLTD_D",
"name":"R_xylitol_dehydrogenase__D_xyulose_forming_",
"metabolites":{
"h_c":1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"xylt_c":-1.0,
"xylu__D_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11790",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"XYLTD_D",
"rhea":"RHEA:20433",
"sbo":"SBO:0000176"
}
},
{
"id":"YUMPS",
"name":"yUMP synthetase",
"metabolites":{
"h2o_c":1.0,
"psd5p_c":1.0,
"r5p_c":-1.0,
"ura_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10130 or KJMKFHIL_19910 or KJMKFHIL_01760 or KJMKFHIL_00180 or KJMKFHIL_03740 or KJMKFHIL_16950",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"YUMPS",
"rhea":"RHEA:18337",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ZNHANT_1",
"name":"\ufeffCadmium, cobalt and zinc/H(+)-K(+) antiporter",
"metabolites":{
"__LactoPanGEM__zn_c":1.0,
"__LactoPanGEM__zn_e":-1.0,
"h_c":-1.0,
"h_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ZNHANT_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ZNKANT_1",
"name":"\ufeffCadmium, cobalt and zinc/H(+)-K(+) antiporter",
"metabolites":{
"__LactoPanGEM__zn_c":1.0,
"__LactoPanGEM__zn_e":-1.0,
"k_c":-1.0,
"k_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ZNKANT_1",
"sbo":"SBO:0000655"
}
},
{
"id":"MNLpts",
"name":"mannitol transport via PEP:Pyr PTS",
"metabolites":{
"mnl1p_c":1.0,
"mnl_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_20600 or KJMKFHIL_02080 or KJMKFHIL_17620 or KJMKFHIL_02090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MNLpts",
"sbo":"SBO:0000655"
}
},
{
"id":"MANpts",
"name":"D-mannose transport via PEP:Pyr PTS",
"metabolites":{
"man6p_c":1.0,
"man_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_11820 or KJMKFHIL_17440 or KJMKFHIL_23780 or KJMKFHIL_27960 or KJMKFHIL_23760 or KJMKFHIL_22480 or KJMKFHIL_22490 or KJMKFHIL_27980 or KJMKFHIL_28000 or KJMKFHIL_17420 or KJMKFHIL_02080 or KJMKFHIL_11580 or KJMKFHIL_02090 or KJMKFHIL_23840",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MANpts",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__RNDR2",
"name":"Ribonucleoside-Diphosphate Reductase (GDP)",
"metabolites":{
"__LactoPanGEM__dgdp_c":1.0,
"__LactoPanGEM__gdp_c":-1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10030 or KJMKFHIL_03290 or KJMKFHIL_13560 or KJMKFHIL_01630 or KJMKFHIL_24740 or KJMKFHIL_10020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNDR2:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLNTAL_1",
"name":"glutamyl-tRNA(Gln):L-glutamine amido-ligase (ADP-forming)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__glntrna_c":1.0,
"__LactoPanGEM__glutrna_c":-1.0,
"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_14320 or KJMKFHIL_14310 or KJMKFHIL_14300",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLNTAL_1",
"sbo":"SBO:0000176"
}
},
{
"id":"TRPS3",
"name":"tryptophan synthase (indoleglycerol phosphate)",
"metabolites":{
"3ig3p_c":-1.0,
"g3p_c":1.0,
"indole_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05450 or KJMKFHIL_05460",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TRPS3",
"sbo":"SBO:0000176"
}
},
{
"id":"FRUpts",
"name":"D-fructose transport via PEP:Pyr PTS",
"metabolites":{
"f1p_c":1.0,
"fru_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12010 or KJMKFHIL_09150 or KJMKFHIL_12030 or KJMKFHIL_02080 or KJMKFHIL_02090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FRUpts",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__PDHam2mi",
"name":"R03270_c0",
"metabolites":{
"__LactoPanGEM__2ahethmpp_c":-1.0,
"__LactoPanGEM__adhlam_c":1.0,
"__LactoPanGEM__thmpp_c":1.0,
"lpam_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10280 or KJMKFHIL_07350 or KJMKFHIL_07360 or KJMKFHIL_07370",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PDHam2mi:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__ATPS3r_1",
"name":"ATP synthase (four protons for one ATP)",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":-2.0,
"h_e":3.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10790 or KJMKFHIL_10800 or KJMKFHIL_10820 or KJMKFHIL_10830 or KJMKFHIL_10840 or KJMKFHIL_10810 or KJMKFHIL_10770 or KJMKFHIL_10780",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ATPS3r_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__GLCpts_1",
"name":"D-glucose transport via PEP:Pyr PTS",
"metabolites":{
"__LactoPanGEM__g6p_c":1.0,
"glc__D_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05180 or KJMKFHIL_12870 or KJMKFHIL_23280 or KJMKFHIL_06540 or KJMKFHIL_02080 or KJMKFHIL_21370 or KJMKFHIL_02090 or KJMKFHIL_24040",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__GLCpts_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ATPPRT_1",
"name":"ATP phosphoribosyltransferase",
"metabolites":{
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__prbatp_c":1.0,
"__LactoPanGEM__prpp_c":-1.0,
"ppi_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_08270 or KJMKFHIL_08260",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ATPPRT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"CELBpts",
"name":"cellobiose transport via PEP:Pyr PTS",
"metabolites":{
"6pgg_c":1.0,
"cellb_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_12650 or KJMKFHIL_19380 or KJMKFHIL_19430 or KJMKFHIL_23640 or KJMKFHIL_19440 or KJMKFHIL_23670 or KJMKFHIL_23660 or KJMKFHIL_02300 or KJMKFHIL_02290 or KJMKFHIL_02270 or KJMKFHIL_02080 or KJMKFHIL_16360 or KJMKFHIL_02090 or KJMKFHIL_12690",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CELBpts",
"sbo":"SBO:0000655"
}
},
{
"id":"SUCpts",
"name":"sucrose transport via PEP:Pyr PTS",
"metabolites":{
"pep_c":-1.0,
"pyr_c":1.0,
"suc6p_c":1.0,
"sucr_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_05180 or KJMKFHIL_12870 or KJMKFHIL_23280 or KJMKFHIL_06540 or KJMKFHIL_02080 or KJMKFHIL_21370 or KJMKFHIL_02090",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SUCpts",
"sbo":"SBO:0000655"
}
},
{
"id":"MALTpts",
"name":"maltose transport via PEP:Pyr PTS",
"metabolites":{
"malt6p_c":1.0,
"malt_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_02080 or KJMKFHIL_02090 or KJMKFHIL_24030",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MALTpts",
"sbo":"SBO:0000655"
}
},
{
"id":"GALTpts",
"name":"Galactitol transport via PEP:Pyr PTS",
"metabolites":{
"galt1p_c":1.0,
"galt_e":-1.0,
"pep_c":-1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_19480 or KJMKFHIL_19490 or KJMKFHIL_15380 or KJMKFHIL_19340 or KJMKFHIL_02090 or KJMKFHIL_02080",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GALTpts",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__MOBUDH",
"name":"3-methyl-2-oxobutanoate dehydrogenase",
"metabolites":{
"2mpdhl_c":1.0,
"__LactoPanGEM__2mhop_c":-1.0,
"__LactoPanGEM__thmpp_c":1.0,
"h_c":1.0,
"lpam_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10260 or KJMKFHIL_10270",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOBUDH",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MOBUDH2",
"name":"3-methyl-2-oxobutanoate dehydrogenase",
"metabolites":{
"__LactoPanGEM__3m1hbtpp_c":1.0,
"__LactoPanGEM__thmpp_c":1.0,
"h_c":2.0,
"lpam_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10260 or KJMKFHIL_10270",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOBUDH2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MOBUDH4",
"name":"3-methyl-2-oxobutanoate dehydrogenase",
"metabolites":{
"2mbdhl_c":1.0,
"__LactoPanGEM__2mehbtpp_c":-1.0,
"__LactoPanGEM__thmpp_c":1.0,
"h_c":1.0,
"lpam_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10260 or KJMKFHIL_10270",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MOBUDH4",
"sbo":"SBO:0000176"
}
},
{
"id":"GAL6PI",
"name":"galactose-6-phosphate isomerase",
"metabolites":{
"dgal6p_c":-1.0,
"tag6p__D_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_15330 or KJMKFHIL_15320",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GAL6PI",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__OSUS",
"name":"oxalosuccinate synthetase",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"akg_c":-1.0,
"h2co3_c":-1.0,
"osuc_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16810 or KJMKFHIL_12960",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__OSUS",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__RNDR1",
"name":"Ribonucleoside-diphosphate reductase (ADP)",
"metabolites":{
"__LactoPanGEM__adp_c":-1.0,
"__LactoPanGEM__dadp_c":1.0,
"__LactoPanGEM__trdox_c":1.0,
"__LactoPanGEM__trdrd_c":-1.0,
"h2o_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_10030 or KJMKFHIL_03290 or KJMKFHIL_13560 or KJMKFHIL_01630 or KJMKFHIL_24740 or KJMKFHIL_10020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__RNDR1:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FOLt_1",
"name":"Folate transport via proton simport",
"metabolites":{
"__LactoPanGEM__fol_c":1.0,
"__LactoPanGEM__fol_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_16310",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__FOLt_1",
"sbo":"SBO:0000655"
}
},
{
"id":"LDH_L",
"name":"L-lactate dehydrogenase",
"metabolites":{
"h_c":1.0,
"lac__L_c":-1.0,
"nad_c":-1.0,
"nadh_c":1.0,
"pyr_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_18910 or KJMKFHIL_23250 or KJMKFHIL_18380 or KJMKFHIL_12620 or KJMKFHIL_12630 or KJMKFHIL_12610 or KJMKFHIL_22170 or KJMKFHIL_07330",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LDH_L",
"rhea":"RHEA:23444",
"sbo":"SBO:0000176"
}
},
{
"id":"TYRt2r",
"name":"L-tyrosine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"tyr__L_c":1.0,
"tyr__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25780 or KJMKFHIL_00380 or KJMKFHIL_23260",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TYRt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"PHEt2r",
"name":"L-phenylalanine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"phe__L_c":1.0,
"phe__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_25780 or KJMKFHIL_00380 or KJMKFHIL_23260",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PHEt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ACLS_1",
"name":"2-Acetolactate pyruvate-lyase (carboxylating)_c0",
"metabolites":{
"__LactoPanGEM__alac__S_DUP3_c":1.0,
"co2_c":1.0,
"h_c":-1.0,
"pyr_c":-2.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"KJMKFHIL_17020",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACLS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__CPSS_LBR_1",
"name":"CPS synthase complex, LRE specific",
"metabolites":{
"__LactoPanGEM__CPS_LBR_c":1.0,
"__LactoPanGEM__gdp_c":1.0,
"__LactoPanGEM__udp_c":4.0,
"gdpmann_c":-2.0,
"gmp_c":1.0,
"h2o_c":-7.0,
"h_c":8.0,
"udpg_c":-3.0,
"udpgal_c":-2.0,
"ump_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CPSS_LBR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"COt",
"name":"CO transporter via diffusion",
"metabolites":{
"co_c":1.0,
"co_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"COt:2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DAD5DIF",
"name":"",
"metabolites":{
"dad_5_c":1.0,
"dad_5_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DAD5DIF",
"sbo":"SBO:0000655"
}
},
{
"id":"BTDt_RR",
"name":"R__R_R__butanediol_transport",
"metabolites":{
"btd_RR_c":-1.0,
"btd_RR_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BTDt_RR",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CBLTDe",
"name":"Release of B12 by SIMPle Diffusion",
"metabolites":{
"__LactoPanGEM__adocbl_c":-1.0,
"__LactoPanGEM__adocbl_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CBLTDe",
"sbo":"SBO:0000655"
}
},
{
"id":"CO2t",
"name":"CO2 transporter via diffusion",
"metabolites":{
"co2_c":1.0,
"co2_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"CO2t",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__DDCAt_1",
"name":"Fatty acid (dodecanoate) transport via facilitated irreversible diffusion",
"metabolites":{
"ddca_c":1.0,
"ddca_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DDCAt_1",
"sbo":"SBO:0000655"
}
},
{
"id":"FORt",
"name":"formate transport via diffusion",
"metabolites":{
"for_c":1.0,
"for_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FORt",
"sbo":"SBO:0000655"
}
},
{
"id":"FUMtr",
"name":"Fumarate transport via diffusion",
"metabolites":{
"fum_c":-1.0,
"fum_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FUMtr",
"sbo":"SBO:0000655"
}
},
{
"id":"H2Ot",
"name":"H2O transport via diffusion",
"metabolites":{
"h2o_c":1.0,
"h2o_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"H2Ot",
"sbo":"SBO:0000655"
}
},
{
"id":"H2St1",
"name":"h2s transport via diffusion",
"metabolites":{
"h2s_c":1.0,
"h2s_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"H2St1",
"sbo":"SBO:0000655"
}
},
{
"id":"HDCAt",
"name":"R_Hexadecanoate__n_C160__transport_in_via_uniport",
"metabolites":{
"hdca_c":1.0,
"hdca_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HDCAt",
"sbo":"SBO:0000655"
}
},
{
"id":"INSt",
"name":"Inosine transport (diffusion)",
"metabolites":{
"ins_c":1.0,
"ins_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"INSt",
"sbo":"SBO:0000655"
}
},
{
"id":"O2t",
"name":"O2 transport in via diffusion",
"metabolites":{
"o2_c":1.0,
"o2_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"O2t",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__OCDCAtr_1",
"name":"Fatty Acid Transport via Diffusion",
"metabolites":{
"__LactoPanGEM__ocdca_e":-1.0,
"ocdca_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__OCDCAtr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"OCDCEAt",
"name":"R_Octadecenoate__n_C181__transport_in_via_uniport",
"metabolites":{
"ocdcea_c":1.0,
"ocdcea_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"OCDCEAt",
"sbo":"SBO:0000655"
}
},
{
"id":"ORNt",
"name":"ornithine transport via diffusion (extracellular to cytosol)",
"metabolites":{
"orn__L_c":1.0,
"orn__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ORNt",
"sbo":"SBO:0000655"
}
},
{
"id":"PYDAMtr",
"name":"pyridoxamine transport via diffusion",
"metabolites":{
"pydam_c":1.0,
"pydam_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PYDAMtr",
"sbo":"SBO:0000655"
}
},
{
"id":"PYDXtr",
"name":"pyridoxal transport via diffusion",
"metabolites":{
"pydx_c":1.0,
"pydx_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PYDXtr",
"sbo":"SBO:0000655"
}
},
{
"id":"PYDXNtr",
"name":"pyridoxine transport via diffusion",
"metabolites":{
"pydxn_c":1.0,
"pydxn_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PYDXNtr",
"sbo":"SBO:0000655"
}
},
{
"id":"UREAt",
"name":"Urea transport via facilitate diffusion",
"metabolites":{
"urea_c":1.0,
"urea_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"UREAt",
"sbo":"SBO:0000655"
}
},
{
"id":"LIPOt",
"name":"lipoate transport",
"metabolites":{
"lipoate_c":1.0,
"lipoate_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"LIPOt",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_lipoate_e_1",
"name":"Exchange of (R)-lipoate.",
"metabolites":{
"lipoate_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_lipoate_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_orot_e",
"name":"Exchange of orotate.",
"metabolites":{
"orot_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_orot_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_co_e",
"name":"Carbon monoxide exchange",
"metabolites":{
"co_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_co_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_dad_5_e",
"name":"Exchange of 5'-deoxyadenosine.",
"metabolites":{
"dad_5_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dad_5_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pydam_e",
"name":"Exchange of pyridoxaminium(1+).",
"metabolites":{
"pydam_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pydam_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pydx_e",
"name":"Exchange of pyridoxal.",
"metabolites":{
"pydx_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pydx_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pydxn_e",
"name":"Exchange of pyridoxine.",
"metabolites":{
"pydxn_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pydxn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_12ppd__S_e",
"name":"Exchange of (S)-propane-1,2-diol.",
"metabolites":{
"12ppd__S_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_12ppd__S_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_acgam_e",
"name":"Exchange of N-acetyl-D-glucosamine.",
"metabolites":{
"acgam_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_acgam_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_acnam_e",
"name":"Exchange of N-acetyl-beta-neuraminate.",
"metabolites":{
"acnam_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_acnam_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_fuc__L_e",
"name":"Exchange of alpha-L-fucose.",
"metabolites":{
"fuc__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_fuc__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gal_e",
"name":"Exchange of alpha-D-galactose.",
"metabolites":{
"gal_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gal_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_lac__L_e",
"name":"Exchange of (S)-lactate.",
"metabolites":{
"lac__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_lac__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_lald__L_e",
"name":"Exchange of (S)-lactaldehyde.",
"metabolites":{
"lald__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_lald__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_12dgr180_e",
"name":"Exchange of 1,2-dioctadecanoyl-sn-glycerol.",
"metabolites":{
"12dgr180_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_12dgr180_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_13ppd_e",
"name":"Exchange of propane-1,3-diol.",
"metabolites":{
"13ppd_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_13ppd_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_2ddglcn_e",
"name":"Exchange of 2-dehydro-3-deoxy-D-gluconate.",
"metabolites":{
"2ddglcn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_2ddglcn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_2dmmq8_e",
"name":"Exchange of 2-demethylmenaquinone-8.",
"metabolites":{
"2dmmq8_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_2dmmq8_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_2obut_e",
"name":"Exchange of 2-oxobutanoate.",
"metabolites":{
"2obut_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_2obut_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_34dhpha_e",
"name":"Exchange of (3,4-dihydroxyphenyl)acetate.",
"metabolites":{
"34dhpha_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_34dhpha_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_34dhphe_e",
"name":"Exchange of L-dopa zwitterion.",
"metabolites":{
"34dhphe_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_34dhphe_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_3mop_e",
"name":"Exchange of (S)-3-methyl-2-oxovalerate.",
"metabolites":{
"3mop_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_3mop_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_4abut_e",
"name":"Exchange of gamma-aminobutyric acid zwitterion.",
"metabolites":{
"4abut_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_4abut_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_4abz_e",
"name":"Exchange of 4-aminobenzoate.",
"metabolites":{
"4abz_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_4abz_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_4hbz_e",
"name":"Exchange of 4-hydroxybenzoate.",
"metabolites":{
"4hbz_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_4hbz_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_5htrp_e",
"name":"_5-Hydroxy-L-tryptophan exchange",
"metabolites":{
"5htrp_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_5htrp_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__5mthf_e_1",
"name":"exchange reaction for 5-Methyltetrahydrofolate",
"metabolites":{
"__LactoPanGEM__5mthf_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__5mthf_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ac_e",
"name":"Exchange of acetate.",
"metabolites":{
"ac_e":-1.0
},
"lower_bound":-2.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ac_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_acald_e",
"name":"Exchange of acetaldehyde.",
"metabolites":{
"acald_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_acald_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ade_e",
"name":"Exchange of adenine.",
"metabolites":{
"ade_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ade_e",
"sbo":"SBO:0000627"
}
},
{
"id":"ADNt2",
"name":"adenosine transport in via proton symport",
"metabolites":{
"adn_c":1.0,
"adn_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ADNt2",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_adn_e",
"name":"Exchange of adenosine.",
"metabolites":{
"adn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_adn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__adocbl_e",
"name":"Adenosylcobalamin exchange",
"metabolites":{
"__LactoPanGEM__adocbl_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__adocbl_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ahcys_e",
"name":"Exchange of S-adenosyl-L-homocysteine zwitterion.",
"metabolites":{
"ahcys_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ahcys_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_akg_e",
"name":"Exchange of 2-oxoglutarate(2-).",
"metabolites":{
"akg_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_akg_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ala__D_e",
"name":"Exchange of D-alanine zwitterion.",
"metabolites":{
"ala__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ala__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ala__L_e",
"name":"Exchange of L-alanine zwitterion.",
"metabolites":{
"ala__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ala__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__alltn_e",
"name":"Allantoin exchange",
"metabolites":{
"__LactoPanGEM__alltn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__alltn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"AMPt6",
"name":"R_AMP_transport_inout_via_proton_symport",
"metabolites":{
"amp_c":1.0,
"amp_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"AMPt6",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_amp_e",
"name":"Exchange of adenosine 5'-monophosphate(2-).",
"metabolites":{
"amp_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_amp_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_arab__L_e",
"name":"L-Arabinose exchange",
"metabolites":{
"arab__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_arab__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_arbt_e",
"name":"Exchange of hydroquinone O-beta-D-glucopyranoside.",
"metabolites":{
"arbt_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_arbt_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_arg__L_e",
"name":"Exchange of L-argininium(1+).",
"metabolites":{
"arg__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_arg__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__arsenb_e",
"name":"Arsenobetaine exchange",
"metabolites":{
"__LactoPanGEM__arsenb_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__arsenb_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_asn__L_e",
"name":"Exchange of L-asparagine zwitterion.",
"metabolites":{
"asn__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_asn__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_asp__L_e",
"name":"Exchange of L-aspartate(1-).",
"metabolites":{
"asp__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_asp__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_btd_RR_e",
"name":"Exchange of (R,R)-butane-2,3-diol.",
"metabolites":{
"btd_RR_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_btd_RR_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_btn_e",
"name":"Exchange of biotinate.",
"metabolites":{
"btn_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_btn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_butso3_e",
"name":"Exchange of butane-1-sulfonate.",
"metabolites":{
"butso3_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_butso3_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_C02528_e",
"name":"Exchange of chenodeoxycholate.",
"metabolites":{
"C02528_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_C02528_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cd2_e",
"name":"Exchange of cadmium(2+).",
"metabolites":{
"cd2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cd2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cellb_e",
"name":"Exchange of cellobiose.",
"metabolites":{
"cellb_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cellb_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cgly_e",
"name":"Exchange of L-cysteinylglycine zwitterion.",
"metabolites":{
"cgly_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cgly_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_chol_e",
"name":"Exchange of choline.",
"metabolites":{
"chol_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_chol_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cholate_e",
"name":"Exchange of cholate.",
"metabolites":{
"cholate_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cholate_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_chols_e",
"name":"Exchange of choline sulfate.",
"metabolites":{
"chols_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_chols_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cit_e",
"name":"Exchange of citrate(3-).",
"metabolites":{
"cit_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cit_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_csn_e",
"name":"Exchange of cytosine.",
"metabolites":{
"csn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_csn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ctbt_e",
"name":"Crotonobetaine exchange",
"metabolites":{
"__LactoPanGEM__ctbt_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ctbt_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cys__L_e",
"name":"Exchange of L-cysteine zwitterion.",
"metabolites":{
"cys__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cys__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_cytd_e",
"name":"Exchange of cytidine.",
"metabolites":{
"cytd_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_cytd_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_dad_2_e",
"name":"Exchange of 2'-deoxyadenosine.",
"metabolites":{
"dad_2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dad_2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_dcyt_e",
"name":"Exchange of 2'-deoxycytidine.",
"metabolites":{
"dcyt_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dcyt_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ddca_e",
"name":"Exchange of dodecanoate.",
"metabolites":{
"ddca_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ddca_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__dextrin_e",
"name":"Dextrin exchange",
"metabolites":{
"__LactoPanGEM__dextrin_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__dextrin_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_dgsn_e",
"name":"Exchange of 2'-deoxyguanosine.",
"metabolites":{
"dgsn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dgsn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_diact_e",
"name":"Exchange of butane-2,3-dione.",
"metabolites":{
"diact_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_diact_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_din_e",
"name":"Exchange of 2'-deoxyinosine.",
"metabolites":{
"din_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_din_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_dopa_e",
"name":"Exchange of dopaminium(1+).",
"metabolites":{
"dopa_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dopa_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_dpcoa_e",
"name":"Exchange of 3'-dephospho-CoA(2-).",
"metabolites":{
"dpcoa_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dpcoa_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_drib_e",
"name":"Exchange of 2-deoxy-D-ribofuranose.",
"metabolites":{
"drib_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_drib_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_etha_e",
"name":"Exchange of ethanolaminium(1+).",
"metabolites":{
"etha_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_etha_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_eths_e",
"name":"Exchange of ethanesulfonate.",
"metabolites":{
"eths_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_eths_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_etoh_e",
"name":"Exchange of ethanol.",
"metabolites":{
"etoh_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_etoh_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__fecrm_e",
"name":"Ferrichrome exchange",
"metabolites":{
"__LactoPanGEM__fecrm_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__fecrm_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__fol_e_1",
"name":"exchange reaction for Folate",
"metabolites":{
"__LactoPanGEM__fol_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__fol_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_for_e",
"name":"Exchange of formate.",
"metabolites":{
"for_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_for_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_fru_e",
"name":"Exchange of beta-D-fructofuranose.",
"metabolites":{
"fru_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_fru_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_fum_e",
"name":"Exchange of fumarate(2-).",
"metabolites":{
"fum_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_fum_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_galt_e",
"name":"Exchange of galactitol.",
"metabolites":{
"galt_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_galt_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_galur_e",
"name":"Exchange of aldehydo-D-galacturonate.",
"metabolites":{
"galur_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_galur_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gam_e",
"name":"Exchange of 2-ammonio-2-deoxy-D-glucopyranose.",
"metabolites":{
"gam_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gam_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gcald_e",
"name":"R_Glycolaldehyde_exchange",
"metabolites":{
"gcald_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gcald_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gchola_e",
"name":"Glycocholate exchange",
"metabolites":{
"__LactoPanGEM__gchola_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gchola_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glc__D_e",
"name":"Exchange of D-glucopyranose.",
"metabolites":{
"glc__D_e":-1.0
},
"lower_bound":-20.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glc__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glcn_e",
"name":"Exchange of D-gluconate.",
"metabolites":{
"glcn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glcn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glcur_e",
"name":"Exchange of D-glucopyranuronate.",
"metabolites":{
"glcur_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glcur_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gln__L_e",
"name":"Exchange of L-glutamine zwitterion.",
"metabolites":{
"gln__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gln__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glu__L_e",
"name":"Exchange of L-glutamate(1-).",
"metabolites":{
"glu__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glu__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gly_e",
"name":"Exchange of glycine zwitterion.",
"metabolites":{
"gly_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gly_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glyb_e",
"name":"Exchange of glycine betaine.",
"metabolites":{
"glyb_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glyb_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glyc_e",
"name":"Exchange of glycerol.",
"metabolites":{
"glyc_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glyc_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_glyclt_e",
"name":"Exchange of glycolate.",
"metabolites":{
"glyclt_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_glyclt_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gsn_e",
"name":"Exchange of guanosine.",
"metabolites":{
"gsn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gsn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gthox_e",
"name":"Exchange of glutathione disulfide(2-).",
"metabolites":{
"gthox_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gthox_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gthrd_e",
"name":"Exchange of glutathionate(1-).",
"metabolites":{
"gthrd_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gthrd_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_gua_e",
"name":"Exchange of guanine.",
"metabolites":{
"gua_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_gua_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_h2_e",
"name":"Exchange of dihydrogen.",
"metabolites":{
"h2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_h2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_h2s_e_1",
"name":"Exchange of hydrosulfide.",
"metabolites":{
"h2s_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_h2s_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_hdca_e",
"name":"Exchange of hexadecanoate.",
"metabolites":{
"hdca_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_hdca_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__hexs_e_1",
"name":"Hexanesulfonate exchange",
"metabolites":{
"__LactoPanGEM__hexs_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__hexs_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_hg2_e",
"name":"Exchange of mercury(2+).",
"metabolites":{
"hg2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_hg2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_his__L_e",
"name":"Exchange of L-histidine zwitterion.",
"metabolites":{
"his__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_his__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_hista_e",
"name":"Exchange of histaminium.",
"metabolites":{
"hista_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_hista_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_hxan_e",
"name":"Exchange of hypoxanthine.",
"metabolites":{
"hxan_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_hxan_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ile__L_e",
"name":"Exchange of L-isoleucine zwitterion.",
"metabolites":{
"ile__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ile__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ind3ac_e",
"name":"Exchange of indole-3-acetate.",
"metabolites":{
"ind3ac_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ind3ac_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ascb__L_e",
"name":"ascorbat exchange",
"metabolites":{
"__LactoPanGEM__ascb__L_e":-1.0
},
"lower_bound":-0.5,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ascb__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_indole_e",
"name":"Indole exchange",
"metabolites":{
"indole_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_indole_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_inost_e",
"name":"Exchange of myo-inositol.",
"metabolites":{
"inost_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_inost_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ins_e",
"name":"Exchange of inosine.",
"metabolites":{
"ins_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ins_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_lac__D_e",
"name":"Exchange of (R)-lactate.",
"metabolites":{
"lac__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_lac__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_lcts_e",
"name":"Exchange of lactose.",
"metabolites":{
"lcts_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_lcts_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_Lcyst_e",
"name":"Exchange of L-cysteate(1-).",
"metabolites":{
"Lcyst_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_Lcyst_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_leu__L_e",
"name":"Exchange of L-leucine zwitterion.",
"metabolites":{
"leu__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_leu__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_lys__L_e",
"name":"Exchange of L-lysinium(1+).",
"metabolites":{
"lys__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_lys__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_mal__L_e",
"name":"Exchange of (S)-malate(2-).",
"metabolites":{
"mal__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_mal__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_malt_e",
"name":"Exchange of maltose.",
"metabolites":{
"malt_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_malt_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__malthx_e",
"name":"Maltohexaose exchange",
"metabolites":{
"__LactoPanGEM__malthx_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__malthx_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__malttr_e",
"name":"Maltotriose exchange",
"metabolites":{
"__LactoPanGEM__malttr_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__malttr_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_man_e",
"name":"Exchange of D-mannopyranose.",
"metabolites":{
"man_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_man_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_melib_e",
"name":"Exchange of melibiose.",
"metabolites":{
"melib_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_melib_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_met__D_e",
"name":"Exchange of D-methionine zwitterion.",
"metabolites":{
"met__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_met__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_met__L_e",
"name":"Exchange of L-methionine zwitterion.",
"metabolites":{
"met__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_met__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_metsox_S__L_e",
"name":"Exchange of L-methionine (S)-S-oxide zwitterion.",
"metabolites":{
"metsox_S__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_metsox_S__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_mnl_e",
"name":"Exchange of D-mannitol.",
"metabolites":{
"mnl_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_mnl_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__mops_e_1",
"name":"3-(n-Morpholino)Propanesulfonic Acid exchange",
"metabolites":{
"__LactoPanGEM__mops_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__mops_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_mqn8_e",
"name":"Exchange of menaquinone-8.",
"metabolites":{
"mqn8_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_mqn8_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_mso3_e",
"name":"Exchange of methanesulfonate.",
"metabolites":{
"mso3_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_mso3_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_n2o_e",
"name":"Exchange of dinitrogen oxide.",
"metabolites":{
"n2o_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_n2o_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_nac_e",
"name":"Exchange of nicotinate.",
"metabolites":{
"nac_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_nac_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ncam_e",
"name":"Exchange of nicotinamide.",
"metabolites":{
"ncam_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ncam_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ni2_e",
"name":"Exchange of nickel(2+).",
"metabolites":{
"ni2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ni2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_nmn_e",
"name":"Exchange of NMN(-).",
"metabolites":{
"nmn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_nmn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_no_e",
"name":"Exchange of nitric oxide.",
"metabolites":{
"no_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_no_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_no2_e",
"name":"Nitrite exchange",
"metabolites":{
"no2_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_no2_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_no3_e",
"name":"Exchange of nitrate.",
"metabolites":{
"no3_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_no3_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ocdcea_e",
"name":"Exchange of oleate.",
"metabolites":{
"ocdcea_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ocdcea_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_orn__L_e",
"name":"Exchange of L-ornithinium(1+).",
"metabolites":{
"orn__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_orn__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_oxa_e",
"name":"Exchange of oxalate(2-).",
"metabolites":{
"oxa_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_oxa_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__pb_e_1",
"name":"Lead exchange",
"metabolites":{
"__LactoPanGEM__pb_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__pb_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_phe__L_e",
"name":"Exchange of L-phenylalanine zwitterion.",
"metabolites":{
"phe__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_phe__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pheme_e",
"name":"Exchange of ferroheme b(2-).",
"metabolites":{
"pheme_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pheme_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pnto__R_e",
"name":"Exchange of (R)-pantothenate.",
"metabolites":{
"pnto__R_e":-1.0
},
"lower_bound":-0.5,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pnto__R_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_prpnte_e",
"name":"Exchange of propionate.",
"metabolites":{
"prpnte_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_prpnte_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ppi_e",
"name":"Exchange of diphosphate(3-).",
"metabolites":{
"ppi_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ppi_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_pro__L_e",
"name":"Exchange of L-proline zwitterion.",
"metabolites":{
"pro__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pro__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_q8_e",
"name":"Exchange of ubiquinone-8.",
"metabolites":{
"q8_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_q8_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_raffin_e",
"name":"Exchange of raffinose.",
"metabolites":{
"raffin_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_raffin_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_rib__D_e",
"name":"Exchange of D-ribofuranose.",
"metabolites":{
"rib__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_rib__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ribflv_e_1",
"name":"Exchange of riboflavin(1-).",
"metabolites":{
"ribflv_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ribflv_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_rmn_e",
"name":"Exchange of L-rhamnopyranose.",
"metabolites":{
"rmn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_rmn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_salcn_e",
"name":"Exchange of salicin.",
"metabolites":{
"salcn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_salcn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_sbt__D_e",
"name":"Exchange of D-glucitol.",
"metabolites":{
"sbt__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_sbt__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ser__D_e",
"name":"Exchange of D-serine zwitterion.",
"metabolites":{
"ser__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ser__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ser__L_e",
"name":"Exchange of L-serine zwitterion.",
"metabolites":{
"ser__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ser__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_sheme_e",
"name":"Exchange of siroheme(8-).",
"metabolites":{
"sheme_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_sheme_e",
"sbo":"SBO:0000627"
}
},
{
"id":"__LactoPanGEM__SPMDtr_1",
"name":"spermidine transport",
"metabolites":{
"h_c":1.0,
"spmd_c":1.0,
"spmd_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SPMDtr_1",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_spmd_e",
"name":"Exchange of spermidine(3+).",
"metabolites":{
"spmd_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_spmd_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_srtn_e",
"name":"Exchange of serotonin(1+).",
"metabolites":{
"srtn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_srtn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_succ_e",
"name":"Exchange of succinate(2-).",
"metabolites":{
"succ_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_succ_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_sucr_e",
"name":"Exchange of sucrose.",
"metabolites":{
"sucr_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_sucr_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_sulfac_e",
"name":"Exchange of sulfonatoacetate.",
"metabolites":{
"sulfac_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_sulfac_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_taur_e",
"name":"Exchange of taurine zwitterion.",
"metabolites":{
"taur_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_taur_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_tchola_e_1",
"name":"Exchange of taurocholate.",
"metabolites":{
"tchola_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_tchola_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__tdchola_e_1",
"name":"taurochenodeoxycholate exchange",
"metabolites":{
"__LactoPanGEM__tdchola_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__tdchola_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_thf_e",
"name":"Exchange of (6S)-5,6,7,8-tetrahydrofolate(2-).",
"metabolites":{
"thf_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_thf_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_thm_e",
"name":"Exchange of thiamine(1+).",
"metabolites":{
"thm_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_thm_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_thr__L_e",
"name":"Exchange of L-threonine zwitterion.",
"metabolites":{
"thr__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_thr__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_thymd_e",
"name":"Exchange of thymidine.",
"metabolites":{
"thymd_e":-1.0
},
"lower_bound":-0.1,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_thymd_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_tre_e",
"name":"Exchange of alpha,alpha-trehalose.",
"metabolites":{
"tre_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_tre_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_trp__L_e",
"name":"Exchange of L-tryptophan zwitterion.",
"metabolites":{
"trp__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_trp__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_trypta_e",
"name":"Exchange of tryptaminium.",
"metabolites":{
"trypta_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_trypta_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__tsul_e",
"name":"Thiosulfate exchange",
"metabolites":{
"__LactoPanGEM__tsul_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__tsul_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ttdca_e",
"name":"Exchange of tetradecanoate.",
"metabolites":{
"ttdca_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ttdca_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_tym_e",
"name":"Exchange of tyraminium.",
"metabolites":{
"tym_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_tym_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_tyr__L_e",
"name":"Exchange of L-tyrosine zwitterion.",
"metabolites":{
"tyr__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_tyr__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ura_e",
"name":"Exchange of uracil.",
"metabolites":{
"ura_e":-1.0
},
"lower_bound":-2.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ura_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_urea_e",
"name":"Exchange of urea.",
"metabolites":{
"urea_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_urea_e",
"sbo":"SBO:0000627"
}
},
{
"id":"URIt",
"name":"uridine facilated transport in cytosol",
"metabolites":{
"uri_c":-1.0,
"uri_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"URIt",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_uri_e",
"name":"Exchange of uridine.",
"metabolites":{
"uri_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_uri_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_val__L_e",
"name":"Exchange of L-valine zwitterion.",
"metabolites":{
"val__L_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_val__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_xyl__D_e",
"name":"Exchange of D-xylopyranose.",
"metabolites":{
"xyl__D_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_xyl__D_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_actn__S_e",
"name":"Exchange of (S)-acetoin.",
"metabolites":{
"actn__S_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_actn__S_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_ala_L_asp__L_e",
"name":"Exchange of Ala-Asp(1-).",
"metabolites":{
"ala_L_asp__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_ala_L_asp__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ala_gln_e",
"name":"L-alanyl-L-glutamine exchange",
"metabolites":{
"__LactoPanGEM__ala_gln_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ala_gln_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ala_L_glu__L_e_1",
"name":"L-alanyl-L-glutamate exchange",
"metabolites":{
"__LactoPanGEM__ala_L_glu__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ala_L_glu__L_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_L_alagly_e",
"name":"Exchange of Ala-Gly zwitterion.",
"metabolites":{
"L_alagly_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_L_alagly_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ala_his_e",
"name":"L-alanyl-L-histidine exchange",
"metabolites":{
"__LactoPanGEM__ala_his_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ala_his_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ala_leu_e",
"name":"L-alanyl-L-leucine exchange",
"metabolites":{
"__LactoPanGEM__ala_leu_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ala_leu_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__ala_L_thr__L_e",
"name":"L-alanyl-L-threonine exchange",
"metabolites":{
"__LactoPanGEM__ala_L_thr__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__ala_L_thr__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__carn_e",
"name":"exchange reaction for L-Carnitine",
"metabolites":{
"__LactoPanGEM__carn_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__carn_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_asn__L_e",
"name":"Glycyl-L-asparagine exchange",
"metabolites":{
"__LactoPanGEM__gly_asn__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_asn__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_asp__L_e_1",
"name":"Glycyl-L-aspartate exchange",
"metabolites":{
"__LactoPanGEM__gly_asp__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_asp__L_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_cys_e",
"name":"Gly-Cys exchange reaction",
"metabolites":{
"__LactoPanGEM__gly_cys_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_cys_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_gln_e",
"name":"Glycyl-L-glutamine exchange",
"metabolites":{
"__LactoPanGEM__gly_gln_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_gln_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_glu__L_e_1",
"name":"Glycyl-L-glutamate exchange",
"metabolites":{
"__LactoPanGEM__gly_glu__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_glu__L_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_leu_e",
"name":"Glycylleucine exchange",
"metabolites":{
"__LactoPanGEM__gly_leu_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_leu_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_met_e",
"name":"Glycyl-L-methionine exchange",
"metabolites":{
"__LactoPanGEM__gly_met_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_met_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_phe_e",
"name":"exchange reaction for glycylphenylalaine",
"metabolites":{
"__LactoPanGEM__gly_phe_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_phe_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_pro__L_e",
"name":"Glycylproline exchange",
"metabolites":{
"__LactoPanGEM__gly_pro__L_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_pro__L_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__gly_tyr_e",
"name":"Glycyl-L-tyrosine exchange",
"metabolites":{
"__LactoPanGEM__gly_tyr_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__gly_tyr_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_isetac_e",
"name":"Exchange of isethionate.",
"metabolites":{
"isetac_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_isetac_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__mnt_c",
"name":"Mannotriose exchange",
"metabolites":{
"__LactoPanGEM__mnt_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Intracellular demand",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__mnt_c",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__metox__R_e",
"name":"L-methionine-R-sulfoxide exchange",
"metabolites":{
"__LactoPanGEM__metox__R_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__metox__R_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX___LactoPanGEM__Ser_Thr_e_1",
"name":"protein-linked serine or threonine residue (O-glycosylation site) exchange",
"metabolites":{
"__LactoPanGEM__Ser_Thr_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__Ser_Thr_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_stys_e",
"name":"Exchange of stachyose.",
"metabolites":{
"stys_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_stys_e",
"sbo":"SBO:0000627"
}
},
{
"id":"EX_xan_e",
"name":"Xanthine exchange",
"metabolites":{
"xan_e":-1.0
},
"lower_bound":-1.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_xan_e",
"sbo":"SBO:0000627"
}
},
{
"id":"__LactoPanGEM__SPTETDH_1",
"name":"Spontaneous Reaction  tethdp dehydration",
"metabolites":{
"__LactoPanGEM__l2am6ox_c":-1.0,
"h2o_c":1.0,
"thdp_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SPTETDH_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__SPPDHY_1",
"name":"L-4-Hydroxyglutamate semialdehyde hydration (Spontaneous Reaction )",
"metabolites":{
"1p3h5c_c":-1.0,
"4hglusa_c":1.0,
"h2o_c":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SPPDHY_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__DHAMU_1",
"name":"Dehydroalanine mutarotation (Spontaneous Reaction )",
"metabolites":{
"__LactoPanGEM__dehala_c":-1.0,
"__LactoPanGEM__imiprnte_c":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__DHAMU_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__13PPDt",
"name":"1,3-propanediol transporter via diffusion",
"metabolites":{
"13ppd_c":1.0,
"13ppd_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__13PPDt",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ACTNdiff",
"name":"S acetoin diffusion",
"metabolites":{
"actn__S_c":1.0,
"actn__S_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"spontaneous",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACTNdiff",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__L_LACt2_2",
"name":"L-lactate reversible transport via proton symport",
"metabolites":{
"h_c":2.0,
"h_e":-2.0,
"lac__L_c":1.0,
"lac__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__L_LACt2_2",
"sbo":"SBO:0000655"
}
},
{
"id":"ACt2r",
"name":"acetate reversible transport via proton symport",
"metabolites":{
"ac_c":1.0,
"ac_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ACt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__ACALDt_1",
"name":"acetolactate transport in/out via proton symport",
"metabolites":{
"acald_c":1.0,
"acald_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__ACALDt_1",
"sbo":"SBO:0000655"
}
},
{
"id":"DRIBt2",
"name":"deoxyribose transport in via proton symporter",
"metabolites":{
"drib_c":1.0,
"drib_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DRIBt2",
"sbo":"SBO:0000655"
}
},
{
"id":"4ABZt",
"name":"R_4_Aminobenzoate_mitochondrial_transport_via_diffusion",
"metabolites":{
"4abz_c":1.0,
"4abz_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"4ABZt",
"sbo":"SBO:0000655"
}
},
{
"id":"EX___LactoPanGEM__4ahmmp_e_1",
"name":"",
"metabolites":{
"__LactoPanGEM__4ahmmp_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX___LactoPanGEM__4ahmmp_e_1",
"sbo":"SBO:0000627"
}
},
{
"id":"THRt2r",
"name":"L-threonine transport in via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"thr__L_c":1.0,
"thr__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THRt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"PIt2r",
"name":"phosphate reversible transport via symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"pi_c":1.0,
"pi_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PIt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"ETOHt",
"name":"ethanol reversible transport",
"metabolites":{
"etoh_c":1.0,
"etoh_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ETOHt",
"sbo":"SBO:0000655"
}
},
{
"id":"DHAt",
"name":"Dihydroxyacetone transport via facilitated diffusion",
"metabolites":{
"dha_c":1.0,
"dha_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"DHAt",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_dha_e",
"name":"Exchange of dihydroxyacetone.",
"metabolites":{
"dha_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_dha_e",
"sbo":"SBO:0000627"
}
},
{
"id":"GCALDt",
"name":"R_Glycoaldehydye_reversible_transport",
"metabolites":{
"gcald_c":1.0,
"gcald_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GCALDt",
"sbo":"SBO:0000655"
}
},
{
"id":"THMDt2",
"name":"thymidine transport in via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"thymd_c":1.0,
"thymd_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"THMDt2",
"sbo":"SBO:0000655"
}
},
{
"id":"PYRt2",
"name":"pyruvate reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"pyr_c":1.0,
"pyr_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"PYRt2",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_pyr_e",
"name":"Exchange of pyruvate.",
"metabolites":{
"pyr_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_pyr_e",
"sbo":"SBO:0000627"
}
},
{
"id":"ASNt2r",
"name":"L-asparagine reversible transport via proton symport",
"metabolites":{
"asn__L_c":1.0,
"asn__L_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASNt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"TRPt2r",
"name":"L-tryptophan reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"trp__L_c":1.0,
"trp__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TRPt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"SERt2r",
"name":"L-serine reversible transport via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"ser__L_c":1.0,
"ser__L_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SERt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"GUAt2r",
"name":"guanine transport in via proton symport",
"metabolites":{
"gua_c":1.0,
"gua_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GUAt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__HISabc_1",
"name":"L-histidine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"his__L_c":1.0,
"his__L_e":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__HISabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"FUCt",
"name":"L-fucose transport via proton symport",
"metabolites":{
"fuc__L_c":1.0,
"fuc__L_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FUCt",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__CYSDabc_1",
"name":"D-cysteine transport via ABC system",
"metabolites":{
"__LactoPanGEM__adp_c":1.0,
"__LactoPanGEM__atp_c":-1.0,
"__LactoPanGEM__cys__D_c":1.0,
"__LactoPanGEM__cys__D_e":-1.0,
"h2o_c":-1.0,
"h_c":1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__CYSDabc_1",
"sbo":"SBO:0000655"
}
},
{
"id":"FE2t",
"name":"iron (II) transport",
"metabolites":{
"fe2_c":1.0,
"fe2_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"FE2t",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__SUCtpp",
"name":"Sucrose transport via permease",
"metabolites":{
"sucr_c":1.0,
"sucr_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__SUCtpp",
"sbo":"SBO:0000655"
}
},
{
"id":"SUCCt2r",
"name":"Succinate efflux via proton symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"succ_c":1.0,
"succ_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"SUCCt2r",
"sbo":"SBO:0000655"
}
},
{
"id":"GALt2",
"name":"D-galactose transport in via proton symport",
"metabolites":{
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"gal_e":-1.0,
"h_c":1.0,
"h_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"GALt2",
"sbo":"SBO:0000655"
}
},
{
"id":"MALTt2",
"name":"R_maltose_transport_in_via_proton_symport",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"malt_c":1.0,
"malt_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"MALTt2",
"sbo":"SBO:0000655"
}
},
{
"id":"TREt2",
"name":"R_trehalose_transport_in_via_proton_symporter",
"metabolites":{
"h_c":1.0,
"h_e":-1.0,
"tre_c":1.0,
"tre_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"ORPHAN",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"TREt2",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__PPOHt",
"name":"Propanol transport via diffusion",
"metabolites":{
"ppoh_c":1.0,
"ppoh_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__PPOHt",
"sbo":"SBO:0000655"
}
},
{
"id":"HDCEAt",
"name":"R_hexadecenoate__n_C161__transport_in_via_uniport",
"metabolites":{
"hdcea_c":1.0,
"hdcea_e":-1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"HDCEAt",
"sbo":"SBO:0000655"
}
},
{
"id":"12PPDRte",
"name":"Assumed Passive Diffusion into Extracellular Space",
"metabolites":{
"12ppd__R_c":-1.0,
"12ppd__R_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"12PPDRte",
"sbo":"SBO:0000655"
}
},
{
"id":"12PPDt",
"name":"S-Propane-1,2-diol facilitated transport",
"metabolites":{
"12ppd__S_c":-1.0,
"12ppd__S_e":1.0
},
"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"Diffusion",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"12PPDt",
"sbo":"SBO:0000655"
}
},
{
"id":"EX_12ppd__R_e",
"name":"Exchange of (R)-propane-1,2-diol.",
"metabolites":{
"12ppd__R_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"EXCHANGE",
"subsystem":"Extracellular exchange",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"EX_12ppd__R_e",
"sbo":"SBO:0000627"
}
},
{
"id":"ASPO6",
"name":"L-aspartate oxidase",
"metabolites":{
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"h2o2_c":1.0,
"h_c":1.0,
"iasp_c":1.0,
"o2_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"ASPO6:2",
"rhea":"RHEA:25876",
"sbo":"SBO:0000176"
}
},
{
"id":"BPNT",
"name":"3',5'-bisphosphate nucleotidase",
"metabolites":{
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"h2o_c":-1.0,
"pap_c":-1.0,
"pi_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"BPNT",
"rhea":"RHEA:10040",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__BTMAT1_1",
"name":"Butyryl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase",
"metabolites":{
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"__LactoPanGEM__butacp_c":1.0,
"h_c":-1.0,
"nad_c":1.0,
"nadh_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__BTMAT1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR100y_1",
"name":"Enoyl-[acyl-carrier-protein] reductase (NADPH) (n-C10:0)",
"metabolites":{
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"__LactoPanGEM__tdec2eacp_c":-1.0,
"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__EAR100y_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR120y_1",
"name":"",
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"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__EAR120y_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR140y_1",
"name":"Tetradecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing)",
"metabolites":{
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"__LactoPanGEM__tmrs2eacp_c":-1.0,
"h_c":-1.0,
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__EAR140y_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR160y_1",
"name":"Hexadecanoyl-[acyl-carrier protein]:malonyl-CoA C-acyltransferase(decarboxylating, oxoacyl- and enoyl-reducing)",
"metabolites":{
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"h_c":-1.0,
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"lower_bound":0.0,
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"gene_reaction_rule":"GAP",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__EAR160y_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR180x_1",
"name":"Enoyl-[acyl-carrier-protein] reductase (NADH) (n-C18:0)",
"metabolites":{
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"h_c":-1.0,
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
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},
"annotation":{
"biggr":"__LactoPanGEM__EAR180x_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR60x_1",
"name":"enoyl-[acyl-carrier-protein] reductase (NADH) (n-C6:0)",
"metabolites":{
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"__LactoPanGEM__thex2eacp_c":-1.0,
"h_c":-1.0,
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
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},
"annotation":{
"biggr":"__LactoPanGEM__EAR60x_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__EAR80x_1",
"name":"enoyl-[acyl-carrier-protein] reductase (NADH) (n-C8:0)",
"metabolites":{
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"gene_reaction_rule":"GAP",
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},
"annotation":{
"biggr":"__LactoPanGEM__EAR80x_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__MAN1PT_1",
"name":"Mannose 1 phosphate guanylyltransferase",
"metabolites":{
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"gdpmann_c":1.0,
"h_c":-1.0,
"man1p_c":-1.0,
"ppi_c":1.0
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
"Confidence Level":"0"
},
"annotation":{
"biggr":"__LactoPanGEM__MAN1PT_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__NNDPR_1",
"name":"Nicotinate-Nucleotide Diphosphorylase (Carboxylating)",
"metabolites":{
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"co2_c":1.0,
"h_c":-2.0,
"nicrnt_c":1.0,
"ppi_c":1.0,
"quln_c":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__NNDPR_1",
"sbo":"SBO:0000176"
}
},
{
"id":"QULNS_1",
"name":"quinolinate synthase",
"metabolites":{
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"h2o_c":2.0,
"iasp_c":-1.0,
"pi_c":1.0,
"quln_c":1.0
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
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},
"annotation":{
"biggr":"QULNS_1:2",
"rhea":"RHEA:25888",
"sbo":"SBO:0000176"
}
},
{
"id":"PYDXS",
"name":"Pyridoxal-5-phosphate synthase(ribulose)",
"metabolites":{
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"gln__L_c":-1.0,
"glu__L_c":1.0,
"h2o_c":3.0,
"h_c":1.0,
"pi_c":1.0,
"pydx5p_c":1.0,
"ru5p__D_c":-1.0
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"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
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},
"annotation":{
"biggr":"PYDXS",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__3OXDAM",
"name":"3-Oxooctodecanoyl-ACP:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)",
"metabolites":{
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"__LactoPanGEM__acp_c":1.0,
"__LactoPanGEM__hedacp_c":-1.0,
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"gene_reaction_rule":"GAP",
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},
"annotation":{
"biggr":"__LactoPanGEM__3OXDAM:2",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__GLUt4_1",
"name":"Na+/glutamate symport",
"metabolites":{
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"__LactoPanGEM__na_e":-1.0,
"glu__L_c":1.0,
"glu__L_e":-1.0
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"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__GLUt4_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__TRO2EAO_1",
"name":"trans-Octodec-2-enoyl-ACP:NAD+ oxidoreductase (A-specific)",
"metabolites":{
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"h_c":-1.0,
"nadp_c":1.0,
"nadph_c":-1.0
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"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"notes":{
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},
"annotation":{
"biggr":"__LactoPanGEM__TRO2EAO_1",
"sbo":"SBO:0000176"
}
},
{
"id":"BIOMASS2_7",
"name":"Biomass reaction",
"metabolites":{
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"__LactoPanGEM__DNA_LBR_c":-0.205,
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"__LactoPanGEM__LTAtotal_LBR_c":-0.006,
"__LactoPanGEM__PGlac2_c":-0.009,
"__LactoPanGEM__PROT_LBR_c":-3.311,
"__LactoPanGEM__RNA_LBR_c":-0.926,
"__LactoPanGEM__adp_c":27.2,
"__LactoPanGEM__atp_c":-27.2,
"__LactoPanGEM__udcpdp_c":-0.002,
"coa_c":-0.002,
"h2o_c":-27.2,
"h_c":27.2,
"nad_c":-0.002,
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"pydx5p_c":-1e-06
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"BIOMASS",
"objective_coefficient":1.0,
"subsystem":"Biomass and maintenance functions",
"annotation":{
"biggr":"BIOMASS2_7",
"sbo":"SBO:0000629"
}
},
{
"id":"__LactoPanGEM__ACAPS_1",
"name":"",
"metabolites":{
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"__LactoPanGEM__hacp_c":-1.0,
"accoa_c":-1.0,
"coa_c":1.0
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"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"annotation":{
"biggr":"__LactoPanGEM__ACAPS_1",
"sbo":"SBO:0000176"
}
},
{
"id":"ADCL",
"name":"4-aminobenzoate synthase",
"metabolites":{
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"4adcho_c":-1.0,
"h_c":1.0,
"pyr_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"annotation":{
"biggr":"ADCL",
"rhea":"RHEA:16201",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__AKP1_1",
"name":"Alkaline phosphatase Dihydroneopterin",
"metabolites":{
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"h2o_c":-3.0,
"h_c":2.0,
"pi_c":3.0
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"lower_bound":-1000.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"annotation":{
"biggr":"__LactoPanGEM__AKP1_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__OROTt2_1",
"name":"Orotate transport via proton symport (2 H)",
"metabolites":{
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"h_e":-2.0,
"orot_c":1.0,
"orot_e":-1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"annotation":{
"biggr":"__LactoPanGEM__OROTt2_1",
"sbo":"SBO:0000655"
}
},
{
"id":"__LactoPanGEM__FOLD3_1",
"name":"Dihydropteroate synthase",
"metabolites":{
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"__LactoPanGEM__2ahhmd_c":-1.0,
"dhpt_c":1.0,
"ppi_c":1.0
},
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"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"annotation":{
"biggr":"__LactoPanGEM__FOLD3_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__R03472_1",
"name":"phosphomethylpyrimidine synthase",
"metabolites":{
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"__LactoPanGEM__air_c":-1.0,
"amet_c":-1.0,
"co_c":1.0,
"dad_5_c":1.0,
"for_c":1.0,
"met__L_c":1.0
},
"lower_bound":0.0,
"upper_bound":1000.0,
"gene_reaction_rule":"GAP",
"annotation":{
"biggr":"__LactoPanGEM__R03472_1",
"sbo":"SBO:0000176"
}
},
{
"id":"__LactoPanGEM__FAS_1",
"name":"Fatty acyl ACP synthase",
"metabolites":{
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