KARA1 in 562_70448_json
- ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate)
- 23dhmb_c:-1 + nadp_c:-3 ⇌ alac__S_c:-1 + h_c:1 + nadph_c:-4
- Bounds: (-1000.0, 1000.0)
- Universal Reaction: KARA1
RHEA:22068
- (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + NADPH + H(+)
- View on RHEA
Properties
- Names: 2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)[1,2,3,4,5,6], (isomerizing)[1,4,5], KARA1i[1,4,5], Ketol-acid reductoisomerase[1,4,5], acetohydroxyacidisomeroreductase[1,4,5], (R)-2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)[2,3,6], acetohydroxy acid isomeroreductase[2,3,6], ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate)[2,3,6], acetohydroxy acid isomeroreductase, mitochondrial[3], 2,3-Dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing), chloroplast[6]
Linkouts
- RHEA: 22068 [0], 22069 [0], 22070 [0], 22071 [0]
- GO: 0004455 [0]
- EC: 1.1.1.383 [0], 1.1.1.86 [0]
- MetaCyc Reaction: ACETOLACTREDUCTOISOM-RXN [0,2,3,6], RXN-16061 [0]
- KEGG Reaction: R04439 [0,2,3,6], R03051 [1,4,5]
- seed.reaction: rxn02186 [1], rxn15466 [2], rxn30402 [3], rxn32271 [4], rxn33637 [5], rxn35351 [6]
- MetaNetX Reaction: MNXR107913 [1,4,5], MNXR97523 [2,3,6]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | 23dhmb_c:-1 | (R)-2,3-dihydroxy-3-methylbutanoate | CHEBI:49072 | 1 [L] | 0 |
|
-1 | nadp_c:-3 | NADP(3-) | CHEBI:58349 | 1 [L] | 0 |
 |
1 | alac__S_c:-1 | (2S)-2-hydroxy-2-methyl-3-oxobutanoate | CHEBI:58476 | 1 [R] | 0 |
|
1 | h_c:1 | hydron | CHEBI:15378 | 1 [R] | 0 |
|
1 | nadph_c:-4 | NADPH(4-) | CHEBI:57783 | 1 [R] | 0 |
