INOSTO in 562_77331_json
- myo-Inositol:oxygen oxidoreductase
- inost_c:0 + o2_c:0 ⇌ glcur_c:-1 + h2o_c:0 + h_c:1
- Bounds: (-1000.0, 1000.0)
- Universal Reaction: INOSTO
RHEA:23696
- myo-inositol + O2 = D-glucuronate + H2O + H(+)
- View on RHEA
Properties
- Names: myo-Inositol:oxygen oxidoreductase[1,2,3], Myo-inositol oxygenase[1,2,3]
Linkouts
- RHEA: 23696 [0], 23697 [0], 23698 [0], 23699 [0]
- GO: 0050113 [0]
- EC: 1.13.99.1 [0]
- MetaCyc Reaction: MYO-INOSITOL-OXYGENASE-RXN [0,1,2,3]
- KEGG Reaction: R01184 [0,1,2,3]
- seed.reaction: rxn00880 [1], rxn33148 [2], rxn33155 [3]
- MetaNetX Reaction: MNXR141862 [1,2,3], MNXR100839 [1,2,3]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | inost_c:0 | myo-inositol | CHEBI:17268 | 1 [L] | 0 |
|
-1 | o2_c:0 | dioxygen | CHEBI:15379 | 1 [L] | 0 |
 |
1 | glcur_c:-1 | D-glucopyranuronate | CHEBI:58720 | 1 [R] | 0 |
|
1 | h2o_c:0 | water | CHEBI:15377 | 1 [R] | 0 |
|
1 | h_c:1 | hydron | CHEBI:15378 | 1 [R] | 0 |
MEMOTE Flags
This reaction was flagged in the following MEMOTE tests:
There are a total of 5 reversible oxygen-containing reactions (9.80% of all oxygen-containing reactions): O2tex, O2Stex, INOSTO, EX_o2_e, O2tpp
The directionality of oxygen-producing/-consuming reactions affects the model's ability to grow anaerobically i.e. create faux-anaerobic organisms. This test reports how many of these oxygen-containing reactions are reversible. This test does not have any mandatory 'pass' criteria. Implementation: First, find the metabolite representing atmospheric oxygen in the model on the basis of an internal mapping table or by specifically looking for the formula "O2". Then, find all reactions that produce or consume oxygen and report those that are reversible.