PDE4 in 562_77333_json
- 3',5'-cyclic-nucleotide phosphodiesterase
- 35cgmp_c:-1 + h2o_c:0 → gmp_c:-2 + h_c:1
- Bounds: (0.0, 1000.0)
- Universal Reaction: PDE4
RHEA:16957
- 3',5'-cyclic GMP + H2O = GMP + H(+)
- View on RHEA
Properties
- Names: Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase[1,2], 3',5'-cyclic-GMP 5'-nucleotidohydrolase[1,2], 3',5'-cyclic-GMP phosphodiesterase[1,2], 3',5'-cyclic-nucleotide phosphodiesterase 2[1,2], cGMP phosphodiesterase[1,2], cGMP-PDE[1,2], cyclic 3',5'-GMP phosphodiesterase[1,2], cyclic GMP phosphodiesterase[1,2], cyclic guanosine 3',5'-monophosphate phosphodiesterase[1,2], cyclic guanosine 3',5'-phosphate phosphodiesterase[1,2], guanosine cyclic 3',5'-phosphate phosphodiesterase[1,2], Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase, nucleus[2]
Linkouts
- RHEA: 16957 [0], 16958 [0], 16959 [0], 16960 [0]
- GO: 0047555 [0]
- EC: 3.1.4.35 [0]
- MetaCyc Reaction: 35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN [0,1,2], 3.1.4.17-RXN [1,2]
- KEGG Reaction: R01234 [0,1,2]
- seed.reaction: rxn00920 [1], rxn35440 [2]
- MetaNetX Reaction: MNXR100078 [1,2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | 35cgmp_c:-1 | 3',5'-cyclic GMP(1-) | CHEBI:57746 | 1 [L] | 0 |
|
-1 | h2o_c:0 | water | CHEBI:15377 | 1 [L] | 0 |
 |
1 | gmp_c:-2 | guanosine 5'-monophosphate(2-) | CHEBI:58115 | 1 [R] | 0 |
|
1 | h_c:1 | hydron | CHEBI:15378 | 1 [R] | 0 |
