MOHMT in 562_77341_json
- 3-methyl-2-oxobutanoate hydroxymethyltransferase
- 3mob_c:-1 + h2o_c:0 + mlthf_c:-2 → 2dhp_c:-1 + thf_c:-2
- Bounds: (0.0, 1000.0)
- Universal Reaction: MOHMT
RHEA:11824
- 3-methyl-2-oxobutanoate + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate
- View on RHEA
Properties
- Names: 5,10-Methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase[1,2,3], 3-methyl-2-oxobutanoate hydroxymethyltransferase[1,2,3], 3-methyl-2-oxobutanoatehydroxymethyltransferase[1,2,3], 5,10-Methylenetetrahydrofolate:3-methyl-2-oxobutanoate[1,2,3], 5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase[1,2,3], 5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase[1,2,3], alpha-ketoisovalerate hydroxymethyltransferase[1,2,3], dehydropantoate hydroxymethyltransferase[1,2,3], hydroxymethyltransferase[1,2,3], ketopantoate hydroxymethyltransferase[1,2,3], oxopantoate hydroxymethyltransferase[1,2,3], 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN[3]
Linkouts
- RHEA: 11824 [0], 11825 [0], 11826 [0], 11827 [0]
- GO: 0003864 [0]
- EC: 2.1.2.11 [0]
- MetaCyc Reaction: 3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN [0,1,2,3]
- KEGG Reaction: R01226 [0,1,2,3]
- seed.reaction: rxn00912 [1], rxn17749 [2], rxn30578 [3]
- MetaNetX Reaction: MNXR141870 [1,2,3], MNXR139028 [1,2,3]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | 3mob_c:-1 | 3-methyl-2-oxobutanoate | CHEBI:11851 | 1 [L] | 0 |
|
-1 | h2o_c:0 | water | CHEBI:15377 | 1 [L] | 0 |
|
-1 | mlthf_c:-2 | (6R)-5,10-methylenetetrahydrofolate(2-) | CHEBI:15636 | 1 [L] | 0 |
 |
1 | 2dhp_c:-1 | 2-dehydropantoate | CHEBI:11561 | 1 [R] | 0 |
|
1 | thf_c:-2 | (6S)-5,6,7,8-tetrahydrofolate(2-) | CHEBI:57453 | 1 [R] | 0 |
