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  5. 5fthf_c:-2
5fthf_c:-2 in iAF987
  • (6S)-5-formyltetrahydrofolate(2-)
  • Charge: -2
  • Formula: C20H21N7O7
  • Compartment: c - cytosol
  • Universal Metabolite: 5fthf
CHEBI:57457
  • (6S)-5-formyltetrahydrofolate(2-)
  • Type: Small Molecule
  • InChiKey: VVIAGPKUTFNRDU-STQMWFEESA-L
  • View on ChEBI
Properties
  • Molecular Mass||g/mol: 471.4234[0], 471.0[1]
  • SMILES: [H]C(=O)N1c2c(nc(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1[0], Nc1nc2c(c(=O)[nH]1)N(C=O)[C@@H](CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1)CN2[1]
  • Names: (6S)-5-formyl-5,6,7,8-tetrahydrofolate[0], 5-formyltetrahydrofolate dianion[0], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate[0], 5-Formyltetrahydrofolate[1], (6S)-5-formyl-tetrahydrofolate mono-L-glutamate[1], (6S)-leucovorin[1], 5-CHO-THF[1], 5-CHO-THF monoglutamate[1], 5-formyl-H4F[1], 5-formyl-H4F monoglutamate[1], 5-formyl-THF[1], 5-formyl-THF leucovorin[1], 5-formyl-THF monoglutamate[1], 5-formyl-tetrahydrofolate[1], Folinic acid[1], L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid[1], Leucovorin[1], N5-formyl-H4F[1], N5-formyl-H4F monoglutamate[1], N5-formyl-H4PteGlu1[1], N5-formyl-THF[1], N5-formyl-THF monoglutamate[1], citrovorum factor[1], folinate[1], folinic acid[1], folinic acid monoglutamate[1], formyl-H4F[1], formyl-H4F monoglutamate[1], n5-formyl-thf[1], n5-formyl-thf monoglutamate[1], n5-formyltetrahydrofolate[1], n5-formyltetrahydrofolate monoglutamate[1]
Data Sources: [0] CHEBI:57457 via ChEBI, [1] cpd02197 via ModelSEED
Linkouts
Data Sources: [0] CHEBI:57457 via ChEBI, [1] cpd02197 via ModelSEED
MEMOTE Flags
This metabolite was flagged in the following MEMOTE tests:

A total of 74 (6.67%) metabolites are not produced by any reaction of the model: 12dgr120_c, 12dgr140_c, 12dgr141_c, 12dgr160_c, 12dgr161_c, ...

Orphans are metabolites that are only consumed but not produced by reactions in the model. They may indicate the presence of network and knowledge gaps. Implementation: Find orphan metabolites structurally by considering only reaction equations and bounds. FBA is not carried out.

Reactions involving 5fthf_c in iAF987
  BiGG ID Name Reference Transport Collection-specific Model
  BiGG ID Name Reference Transport Collection-specific Model