BiGG Reaction GHMT2rc in iAM

GHMT2rc in iAM_Pf480

glycinehydroxymethyltransferase,reversible,apicoplast
ser__L_h:0 + thf_h:-2 ⇌ gly_h:0 + h2o_h:0 + mlthf_h:-2
Bounds: (-1000000.0, 1000000.0)
Universal Reaction: GHMT2rc

RHEA:15481

(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
View on RHEA

Properties

Names: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase^{[1,2,3,4,5,6]}, 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase^{[1,2,3,4,5,6]}, Glycine Hydroxymethyltransferase^{[1,2,3,4,5,6]}, L-serine hydroxymethyltransferase^{[1,2,3,4,5,6]}, L-threonine aldolase^{[1,2,3,4,5,6]}, Serine hydroxymethyltransferase^{[1,2,3,4,5,6]}, allothreonine aldolase^{[1,2,3,4,5,6]}, glycine hydroxymethyltransferase^{[1,2,3,4,5,6]}, glycine hydroxymethyltransferase, reversible^{[1,2,3,4,5,6]}, glycinehydroxymethyltransferase-reversible^{[1,2,3,4,5,6]}, serine aldolase^{[1,2,3,4,5,6]}, serine hydroxymethylase^{[1,2,3,4,5,6]}, serine hydroxymethyltransferase^{[1,2,3,4,5,6]}, serine transhydroxymethylase^{[1,2,3,4,5,6]}, threonine aldolase^{[1,2,3,4,5,6]}, GLYOHMETRANS-RXN^[4], GLYOHMETRANS-RXN.e^[6]

Data Sources: [0] 15481 via RHEA, [1] rxn00692 via ModelSEED, [2] rxn19870 via ModelSEED, [3] rxn27914 via ModelSEED, [4] rxn30686 via ModelSEED, [5] rxn33977 via ModelSEED, [6] rxn38130 via ModelSEED

Linkouts

RHEA: 15481 ^[0], 15482 ^[0], 15483 ^[0], 15484 ^[0]
GO: 0004372 ^[0]
EC: 2.1.2.1 ^[0]
MetaCyc Reaction: GLYOHMETRANS-RXN ^{[0,1,2,3,4,5,6]}
KEGG Reaction: R00945 ^{[0,1,2,3,4,5,6]}
seed.reaction: rxn00692 ^[1], rxn19870 ^[2], rxn27914 ^[3], rxn30686 ^[4], rxn33977 ^[5], rxn38130 ^[6]
MetaNetX Reaction: MNXR141852 ^{[1,2,3,4,5,6]}, MNXR139018 ^{[1,2,3,4,5,6]}

Reaction Participants

	BiGG ID	Name	Reference	x [side]
-1	ser__L_h:0	L-serine	CHEBI:33384	1 [R]
-1	thf_h:-2	(6S)-5,6,7,8-tetrahydrofolate(2-)	CHEBI:57453	1 [R]
1	gly_h:0	glycine	CHEBI:57305	1 [L]
1	h2o_h:0	water	CHEBI:15377	1 [L]
1	mlthf_h:-2	(6R)-5,10-methylenetetrahydrofolate(2-)	CHEBI:15636	1 [L]

Gene Reaction Rule

PF3D7_1456100 or PF3D7_1235600

	BiGG ID	Name
	PF3D7_1456100	None
	PF3D7_1235600	None