RHEA:28042
- pyruvate + NAD(+) + CoA = acetyl-CoA + CO2 + NADH
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Properties
- Names: pyruvate dehydrogenase[1,2,3], pyruvate dehydrogenase complex[1,2,3], pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating)[1,2,3], PYRUVDEH-RXN.d[2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | coa_h:-4 | coenzyme A(4-) | CHEBI:57287 | 1 [L] | 0 |
|
-1 | nad_h:-1 | NAD(1-) | CHEBI:57540 | 1 [L] | 0 |
|
-1 | pyr_h:-1 | pyruvate | CHEBI:15361 | 1 [L] | 0 |
 |
1 | accoa_h:-4 | acetyl-CoA(4-) | CHEBI:57288 | 1 [R] | 0 |
|
1 | co2_h:0 | carbon dioxide | CHEBI:16526 | 1 [R] | 0 |
|
1 | nadh_h:-2 | NADH(2-) | CHEBI:57945 | 1 [R] | 0 |
Gene Reaction Rule
PKNH_0605000 and PKNH_0504500 and PKNH_0922300 and PKNH_1235800
