TMDS in iECDH1ME8569_1439
- thymidylate synthase
- dump_c:-2 + mlthf_c:-2 → dhf_c:-2 + dtmp_c:-2
- Bounds: (0.0, 1000.0)
- Universal Reaction: TMDS
RHEA:12104
- dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP
- View on RHEA
Properties
- Names: 5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase[1,2,3], 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase[1,2,3], TMP synthetase[1,2,3], Thymidylate synthase[1,2,3], dTMP synthase[1,2,3], methylenetetrahydrofolate:dUMP C-methyltransferase[1,2,3], thymidylate synthase[1,2,3], thymidylate synthetase[1,2,3], THYMIDYLATESYN-RXN.m[3]
Linkouts
- RHEA: 12104 [0], 12105 [0], 12106 [0], 12107 [0]
- GO: 0004799 [0]
- EC: 2.1.1.45 [0]
- MetaCyc Reaction: THYMIDYLATESYN-RXN [0,1,2,3]
- KEGG Reaction: R02101 [0,1,2,3]
- seed.reaction: rxn01520 [1], rxn29013 [2], rxn32556 [3]
- MetaNetX Reaction: MNXR141921 [1,2,3], MNXR104889 [1,2,3]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | dump_c:-2 | dUMP(2-) | CHEBI:246422 | 1 [L] | 0 |
|
-1 | mlthf_c:-2 | (6R)-5,10-methylenetetrahydrofolate(2-) | CHEBI:15636 | 1 [L] | 0 |
 |
1 | dhf_c:-2 | dihydrofolate(2-) | CHEBI:57451 | 1 [R] | 0 |
|
1 | dtmp_c:-2 | dTMP(2-) | CHEBI:63528 | 1 [R] | 0 |
