FTHFLi in iECSE_1348
- formate-tetrahydrofolate ligase
- atp_c:-4 + for_c:-1 + thf_c:-2 → 10fthf_c:-2 + adp_c:-3 + pi_c:-2
- Bounds: (0.0, 1000.0)
- Universal Reaction: FTHFLi
RHEA:20221
- (6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate
- View on RHEA
Properties
- Names: Formyltetrahydrofolate synthetase[1,2,3], formate-tetrahydrofolate ligase[1,2,3], formate-tetrahydrofolateligase[1,2,3], formate:tetrahydrofolate ligase (ADP-forming)[1,2,3], formyltetrahydrofolate synthetase[1,2,3], tetrahydrofolate formylase[1,2,3], tetrahydrofolic formylase[1,2,3], Formate:tetrahydrofolate ligase (ADP-forming)[1,2,3], 10-formyltetrahydrofolate synthetase[1,2,3], Formate--tetrahydrofolate ligase[1,2,3]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | atp_c:-4 | ATP(4-) | CHEBI:30616 | 1 [L] | 0 |
|
-1 | for_c:-1 | formate | CHEBI:15740 | 1 [L] | 0 |
|
-1 | thf_c:-2 | (6S)-5,6,7,8-tetrahydrofolate(2-) | CHEBI:57453 | 1 [L] | 0 |
 |
1 | 10fthf_c:-2 | (6R)-10-formyltetrahydrofolate(2-) | CHEBI:195366 | 1 [R] | 0 |
|
1 | adp_c:-3 | ADP(3-) | CHEBI:456216 | 1 [R] | 0 |
|
1 | pi_c:-2 | hydrogenphosphate | CHEBI:43474 | 1 [R] | 0 |