GHMT2r in iEcDH1_1363
- glycine hydroxymethyltransferase, reversible
- ser__L_c:0 + thf_c:-2 ⇌ gly_c:0 + h2o_c:0 + mlthf_c:-2
- Bounds: (-1000.0, 1000.0)
- Universal Reaction: GHMT2r
RHEA:15481
- (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine
- View on RHEA
Properties
- Names: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase[1,2,3,4,5,6], 5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase[1,2,3,4,5,6], Glycine Hydroxymethyltransferase[1,2,3,4,5,6], L-serine hydroxymethyltransferase[1,2,3,4,5,6], L-threonine aldolase[1,2,3,4,5,6], Serine hydroxymethyltransferase[1,2,3,4,5,6], allothreonine aldolase[1,2,3,4,5,6], glycine hydroxymethyltransferase[1,2,3,4,5,6], glycine hydroxymethyltransferase, reversible[1,2,3,4,5,6], glycinehydroxymethyltransferase-reversible[1,2,3,4,5,6], serine aldolase[1,2,3,4,5,6], serine hydroxymethylase[1,2,3,4,5,6], serine hydroxymethyltransferase[1,2,3,4,5,6], serine transhydroxymethylase[1,2,3,4,5,6], threonine aldolase[1,2,3,4,5,6], GLYOHMETRANS-RXN[4], GLYOHMETRANS-RXN.e[6]
Linkouts
- RHEA: 15481 [0], 15482 [0], 15483 [0], 15484 [0]
- GO: 0004372 [0]
- EC: 2.1.2.1 [0]
- MetaCyc Reaction: GLYOHMETRANS-RXN [0,1,2,3,4,5,6]
- KEGG Reaction: R00945 [0,1,2,3,4,5,6]
- seed.reaction: rxn00692 [1], rxn19870 [2], rxn27914 [3], rxn30686 [4], rxn33977 [5], rxn38130 [6]
- MetaNetX Reaction: MNXR141852 [1,2,3,4,5,6], MNXR139018 [1,2,3,4,5,6]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | ser__L_c:0 | L-serine | CHEBI:33384 | 1 [R] | 0 |
|
-1 | thf_c:-2 | (6S)-5,6,7,8-tetrahydrofolate(2-) | CHEBI:57453 | 1 [R] | 0 |
 |
1 | gly_c:0 | glycine | CHEBI:57305 | 1 [L] | 0 |
|
1 | h2o_c:0 | water | CHEBI:15377 | 1 [L] | 0 |
|
1 | mlthf_c:-2 | (6R)-5,10-methylenetetrahydrofolate(2-) | CHEBI:15636 | 1 [L] | 0 |
