MTHFD in iPKB_GCF_009874055_1
- methylenetetrahydrofolate dehydrogenase (NADP)
- mlthf_c:-2 + nadp_c:-3 ⇌ methf_c:-1 + nadph_c:-4
- Bounds: (-1000.0, 1000.0)
- Universal Reaction: MTHFD
RHEA:22812
- (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methenyltetrahydrofolate + NADPH
- View on RHEA
Properties
- Names: 5,10-methylenetetrahydrofolate:NADP+ oxidoreductase[1,2,3], 5,10-methylenetetrahydrofolate dehydrogenase[1,2,3], 5,10-methylenetetrahydrofolate:NADP oxidoreductase[1,2,3], Methylenetetrahydrofolate dehydrogenase[1,2,3], Methylenetetrahydrofolate dehydrogenase (NADP+)[1,2,3], N5,N10-methylenetetrahydrofolate dehydrogenase[1,2,3], methylenetetrahydrofolate dehydrogenase[1,2,3], methylenetetrahydrofolate dehydrogenase (NADP(+)) / methenyltetrahydrofolate cyclohydrolase[1,2,3], methylenetetrahydrofolate dehydrogenase (NADP)[1,2,3], methylenetetrahydrofolate dehydrogenase (NADP+)[1,2,3], methylenetetrahydrofolate dehydrogenase (nadp+)[1,2,3], methylenetetrahydrofolatedehydrogenase-NADP[1,2,3]
Linkouts
- RHEA: 22812 [0], 22813 [0], 22814 [0], 22815 [0]
- GO: 0004488 [0]
- EC: 1.5.1.5 [0]
- MetaCyc Reaction: METHYLENETHFDEHYDROG-NADP-RXN [0,1,2,3]
- KEGG Reaction: R01220 [0,1,2,3]
- seed.reaction: rxn00907 [1], rxn30158 [2], rxn32777 [3]
- MetaNetX Reaction: MNXR141865 [1,2,3], MNXR101749 [1,2,3]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | mlthf_c:-2 | (6R)-5,10-methylenetetrahydrofolate(2-) | CHEBI:15636 | 1 [L] | 0 |
|
-1 | nadp_c:-3 | NADP(3-) | CHEBI:58349 | 1 [L] | 0 |
 |
1 | methf_c:-1 | (6R)-5,10-methenyltetrahydrofolate | CHEBI:57455 | 1 [R] | 0 |
|
1 | nadph_c:-4 | NADPH(4-) | CHEBI:57783 | 1 [R] | 0 |
Gene Reaction Rule
CLOINNGCF_009874055_15995
| BiGG ID | Name | |
|---|---|---|
 |
CLOINNGCF_009874055_15995 | CLOINNGCF 009874055 15995 |