Universal:ASNS1
- asparagine synthase (glutamine-hydrolysing)
-
h2o_c + asp__L_c + gln__L_c + atp_c ⇌ asn__L_c + glu__L_c + ppi_c + amp_c + h_c h2o_c:0 + asp__L_c:-1 + gln__L_c:0 + atp_c:-4 ⇌ asn__L_c:0 + glu__L_c:-1 + ppi_c:-3 + amp_c:-2 + h_c:1
RHEA:12228
- L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)
- View on RHEA
Properties
- Names: L-aspartate:L-glutamine amido-ligase (AMP-forming)[1,2,3], AS[1,2,3], AS-B[1,2,3], Asparagine synthase (glutamine-hydrolysing)[1,2,3], asparagine synthase (glutamine-hydrolysing)[1,2,3], asparagine synthetase (glutamine-hydrolysing)[1,2,3], asparagine synthetase B[1,2,3], glutamine-dependent asparagine synthetase[1,2,3], ASNSYNB-RXN.w[3]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
| -1 | h2o_c | water | CHEBI:15377 | 1 [L] | 0 | |
| -1 | asp__L_c | L-aspartate(1-) | CHEBI:29991 | 1 [L] | 0 | |
| -1 | gln__L_c | L-glutamine zwitterion | CHEBI:58359, CHEBI:18050 | 1 [L] | 0 | |
| -1 | atp_c | ATP(4-) | CHEBI:30616 | 1 [L] | 0 | |
| 1 | asn__L_c | L-asparagine zwitterion | CHEBI:58048, CHEBI:17196 | 1 [R] | 0 | |
| 1 | glu__L_c | L-glutamate(1-) | CHEBI:29985 | 1 [R] | 0 | |
| 1 | ppi_c | diphosphate(3-) | CHEBI:33019 | 1 [R] | 0 | |
| 1 | amp_c | adenosine 5'-monophosphate(2-) | CHEBI:456215 | 1 [R] | 0 | |
| 1 | h_c | hydron | CHEBI:15378 | 1 [R] | 0 | |