Universal:FOLR2_1
- Folate reductase
-
h_c + nadph_c + fol_c ⇌ dhf_c + nadp_c h_c:1 + nadph_c:-4 + fol_c:-2 ⇌ dhf_c:-2 + nadp_c:-3
RHEA:31103
- 7,8-dihydrofolate + NADP(+) = folate + NADPH + H(+)
- View on RHEA
Properties
- Names: dihydrofolate:NADP+ oxidoreductase[1], Dihydrofolate:NADP+ oxidoreductase[1], dihydropholate reductase[1], folate reductase[1]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
1 | dhf_c | dihydrofolate(2-) | CHEBI:57451 | 1 [L] | 0 |
|
1 | nadp_c | NADP(3-) | CHEBI:58349 | 1 [L] | 0 |
 |
-1 | h_c | hydron | CHEBI:15378 | 1 [R] | 0 |
|
-1 | nadph_c | NADPH(4-) | CHEBI:57783 | 1 [R] | 0 |
|
-1 | fol_c | folate(2-) | CHEBI:62501 | 1 [R] | 0 |