Universal:GCC2cm
- R_glycine_cleavage_complex__lipoamide___mitochondrial
-
nad_m + dhlam_m ⇌ lpam_m + nadh_m + h_m nad_m:-1 + dhlam_m:0 ⇌ lpam_m:0 + nadh_m:-2 + h_m:1
RHEA:33059
- (R)-dihydrolipoamide + NAD(+) = (R)-lipoamide + NADH + H(+)
- View on RHEA
Properties
- Names: Dihydrolipoamide:NAD+ oxidoreductase[1,3,4,6], Diaphorase[1,3,4,6], Dihydrolipoamide dehydrogenase[1,3,4,6], Dihydrolipoyl dehydrogenase[1,3,4,6], E3 component of alpha-ketoacid dehydrogenase complexes[1,3,4,6], Lipoamide reductase (NADH)[1,3,4,6], Lipoyl dehydrogenase[1,3,4,6], Pyruvate dehydrogenase (dihydrolipoamide dehydrogenase) reversible[1,3,4,6], glycine-cleavage complex (lipoamide)[1,3,4,6], lipoamide dehydrogenase component of PDH complex[1,3,4,6], pyruvate dehydrogenase (dihydrolipoamide dehydrogenase)[1,3,4,6], enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase[2,5], dihydrolipoyl dehydrogenase[2,5], enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase; dihydrolipoyl dehydrogenase[5]
Linkouts
- RHEA: 33059 [0], 33060 [0], 33061 [0], 33062 [0]
- EC: 1.8.1.4 [0]
- KEGG Reaction: R01698 [0,1,3,4,6], R07618 [2,5]
- seed.reaction: rxn01241 [1], rxn15694 [2], rxn27791 [3], rxn27792 [4], rxn31329 [5], rxn38078 [6]
- MetaCyc Reaction: RXN-18331 [1,3,4,6], DIHYDLIPOXN-RXN [1,3,4,6]
- MetaNetX Reaction: MNXR100066 [1,3,4,6], MNXR111220 [2,5]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | nad_m | NAD(1-) | CHEBI:57540 | 1 [L] | 0 |
|
-1 | dhlam_m | (R)-dihydrolipoamide | CHEBI:43711 | 1 [L] | 0 |
 |
1 | lpam_m | (R)-lipoamide | CHEBI:83094 | 1 [R] | 0 |
|
1 | nadh_m | NADH(2-) | CHEBI:57945 | 1 [R] | 0 |
|
1 | h_m | hydron | CHEBI:15378 | 1 [R] | 0 |