Universal:GTHS
- glutathione synthetase
-
glucys_c + gly_c + atp_c ⇌ adp_c + h_c + gthrd_c + pi_c glucys_c:-1 + gly_c:0 + atp_c:-4 ⇌ adp_c:-3 + h_c:1 + gthrd_c:-1 + pi_c:-2
RHEA:13557
- gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)
- View on RHEA
Properties
- Names: gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)[1,2], GSH synthetase[1,2], Glutathione synthetase[1,2], gamma-L-Glutamyl-L-cysteine:glycine ligase (ADP-forming)[1,2], glutathione synthase[1,2], glutathione synthetase[1,2]
Linkouts
- RHEA: 13557 [0], 13558 [0], 13559 [0], 13560 [0]
- GO: 0004363 [0]
- EC: 6.3.2.3 [0]
- MetaCyc Reaction: GLUTATHIONE-SYN-RXN [0,1,2]
- KEGG Reaction: R00497 [0,1,2]
- seed.reaction: rxn00351 [1], rxn27892 [2]
- MetaNetX Reaction: MNXR141837 [1,2], MNXR100450 [1,2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | glucys_c | L-gamma-glutamyl-L-cysteinate(1-) | CHEBI:58173 | 1 [L] | 0 |
|
-1 | gly_c | glycine zwitterion | CHEBI:57305, CHEBI:15428 | 1 [L] | 0 |
|
-1 | atp_c | ATP(4-) | CHEBI:30616 | 1 [L] | 0 |
 |
1 | adp_c | ADP(3-) | CHEBI:456216 | 1 [R] | 0 |
|
1 | h_c | hydron | CHEBI:15378 | 1 [R] | 0 |
|
1 | gthrd_c | glutathionate(1-) | CHEBI:57925 | 1 [R] | 0 |
|
1 | pi_c | hydrogenphosphate | CHEBI:43474 | 1 [R] | 0 |