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Universal:HIBDkt
  • 3-hydroxyisobutyrate dehydrogenase
  • nad_c + 3hmp_c ⇌ nadh_c + h_c + mmalsa__S_c
    nad_c:-1 + 3hmp_c:-1 ⇌ nadh_c:-2 + h_c:1 + mmalsa__S_c:-1
RHEA:31275
  • (S)-3-hydroxy-2-methylpropanoate + NAD(+) = (S)-2-methyl-3-oxopropanoate + NADH + H(+)
  • View on RHEA
Properties
  • Names: 3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase[1,3,4,5,8], 3-hydroxyisobutyrate dehydrogenase[1,3,4,6,7,9], 3-hydroxyacyl-CoA dehydrogenase[2], 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN.e[6], 3-hydroxy-2-methylpropanoate:NAD+ oxidoreductase[9,6,7], beta-hydroxyisobutyrate dehydrogenase[9,6,7], 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN.n[7]
Data Sources: [0] 31275 via RHEA, [1] rxn01480 via ModelSEED, [2] rxn30548 via ModelSEED, [3] rxn32099 via ModelSEED, [4] rxn32100 via ModelSEED, [5] rxn35544 via ModelSEED, [6] rxn37954 via ModelSEED, [7] rxn37955 via ModelSEED, [8] rxn15510 via ModelSEED, [9] rxn17758 via ModelSEED
Linkouts
Data Sources: [0] 31275 via RHEA, [1] rxn01480 via ModelSEED, [2] rxn30548 via ModelSEED, [3] rxn32099 via ModelSEED, [4] rxn32100 via ModelSEED, [5] rxn35544 via ModelSEED, [6] rxn37954 via ModelSEED, [7] rxn37955 via ModelSEED, [8] rxn15510 via ModelSEED, [9] rxn17758 via ModelSEED
Reaction Participants
Stoich. BiGG ID Name Reference x [side] Compartment
-1 nad_c NAD(1-) CHEBI:57540 1 [L] 0
-1 3hmp_c (S)-3-hydroxyisobutyrate CHEBI:62638 1 [L] 0
1 nadh_c NADH(2-) CHEBI:57945 1 [R] 0
1 h_c hydron CHEBI:15378 1 [R] 0
1 mmalsa__S_c (S)-methylmalonate semialdehyde CHEBI:62413 1 [R] 0
In BiGGr Models
Organism Model
Synechocystis sp. PCC 6803 iJN678
Bacillus subtilis subsp. subtilis str. 168 iYO844
Pseudomonas putida KT2440 iJN1463