Universal:HMBS
- hydroxymethylbilane synthase
-
h2o_c + ppbng_c ⇌ nh4_c + hmbil_c h2o_c:0 + ppbng_c:-1 ⇌ nh4_c:1 + hmbil_c:-8 h2o_c:0 + ppbng_c:-1 ⇌ nh4_c:0 + hmbil_c:-8 + h_c:1
RHEA:13185
- 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH4(+)
- View on RHEA
Properties
- Names: porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)[1,2,3,4,5], (4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)[1,2,3,4,5], HMB-synthase[1,2,3,4,5], Porphobilinogen ammonia-lyase (polymerizing)[1,2,3,4,5], Porphobilinogen deaminase[1,2,3,4,5], hydroxymethylbilane synthase[1,2,3,4,5], hydroxymethylbilanesynthase[1,2,3,4,5], porphobilinogen ammonia-lyase (polymerizing)[1,2,3,4,5], porphobilinogen deaminase[1,2,3,4,5], pre-uroporphyrinogen synthase[1,2,3,4,5], uroporphyrinogen I synthase[1,2,3,4,5], uroporphyrinogen I synthetase[1,2,3,4,5], uroporphyrinogen synthase[1,2,3,4,5], uroporphyrinogen synthetase[1,2,3,4,5], OHMETHYLBILANESYN-RXN[4]
Linkouts
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | h2o_c | water | CHEBI:15377 | 1 [L] | 0 |
|
-4 | ppbng_c | porphobilinogen(1-) | CHEBI:58126 | 4 [L] | 0 |
 |
4 | nh4_c | ammonium | CHEBI:28938 | 4 [R] | 0 |
|
1 | hmbil_c | preuroporphyrinogen(8-) | CHEBI:57845 | 1 [R] | 0 |