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Universal:MALSp
  • R_malate_synthase
  • h2o_x + glx_x + accoa_x ⇌ coa_x + h_x + mal__L_x
    h2o_x:0 + glx_x:-1 + accoa_x:-4 ⇌ coa_x:-4 + h_x:1 + mal__L_x:-2
RHEA:18181
  • glyoxylate + acetyl-CoA + H2O = (S)-malate + CoA + H(+)
  • View on RHEA
Properties
  • Names: acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)[1,2,3,4,5], L-Malate glyoxylate-lyase (CoA-acetylating)[1,2,3,4,5], L-malate glyoxylate-lyase (CoA-acetylating)[1,2,3,4,5], Malate Synthase[1,2,3,4,5], glyoxylate transacetase[1,2,3,4,5], glyoxylate transacetylase[1,2,3,4,5], glyoxylic transacetase[1,2,3,4,5], malate condensing enzyme[1,2,3,4,5], malate synthase[1,2,3,4,5], malate synthetase[1,2,3,4,5], malatesynthase[1,2,3,4,5], malic synthetase[1,2,3,4,5], malic-condensing enzyme[1,2,3,4,5]
Data Sources: [0] 18181 via RHEA, [1] rxn00330 via ModelSEED, [2] rxn20162 via ModelSEED, [3] rxn33881 via ModelSEED, [4] rxn34243 via ModelSEED, [5] rxn34244 via ModelSEED
Linkouts
Data Sources: [0] 18181 via RHEA, [1] rxn00330 via ModelSEED, [2] rxn20162 via ModelSEED, [3] rxn33881 via ModelSEED, [4] rxn34243 via ModelSEED, [5] rxn34244 via ModelSEED
Reaction Participants
Stoich. BiGG ID Name Reference x [side] Compartment
-1 h2o_x water CHEBI:15377 1 [L] 0
-1 glx_x glyoxylate CHEBI:36655 1 [L] 0
-1 accoa_x acetyl-CoA(4-) CHEBI:57288 1 [L] 0
1 coa_x coenzyme A(4-) CHEBI:57287 1 [R] 0
1 h_x hydron CHEBI:15378 1 [R] 0
1 mal__L_x (S)-malate(2-) CHEBI:15589 1 [R] 0
In BiGGr
Organism Model
Saccharomyces cerevisiae S288C iMM904
Phaeodactylum tricornutum CCAP 1055/1 iLB1027_lipid