Universal:OIVD1m
- _2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial
-
coa_m + nad_m + 4mop_m ⇌ nadh_m + ivcoa_m + co2_m coa_m:-4 + nad_m:-1 + 4mop_m:-1 ⇌ nadh_m:-2 + ivcoa_m:-4 + co2_m:0
RHEA:25177
- 4-methyl-2-oxopentanoate + NAD(+) + CoA = 3-methylbutanoyl-CoA + CO2 + NADH
- View on RHEA
Properties
- Names: 4-methyl-2-oxopentanoate:NAD+ oxidoreductase (CoA-mehtylpropanoylating)[1,2], (CoA-mehtylpropanoylating)[1,2], 2-oxoisovalerate dehydrogenase (acylating 4-methyl-2-oxopentaoate)[1,2], 2-oxoisovalerate dehydrogenase (acylating- 4-methyl-2-oxopentaoate)[1,2], 4-Methyl-2-oxopentanoate:NAD+ oxidoreductase[1,2], 4-methyl-2-oxopentanoate dehydrogenase (acylating)[1,2], 2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN.m[2]
Linkouts
- RHEA: 25177 [0], 25178 [0], 25179 [0], 25180 [0]
- EC: 1.2.1.25 [0]
- MetaCyc Reaction: 2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN [0,1,2]
- KEGG Reaction: R01651 [0,1,2]
- seed.reaction: rxn01207 [1], rxn27534 [2]
- MetaNetX Reaction: MNXR102172 [1,2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | coa_m | coenzyme A(4-) | CHEBI:57287 | 1 [L] | 0 |
|
-1 | nad_m | NAD(1-) | CHEBI:57540 | 1 [L] | 0 |
|
-1 | 4mop_m | 4-methyl-2-oxopentanoate | CHEBI:17865 | 1 [L] | 0 |
 |
1 | nadh_m | NADH(2-) | CHEBI:57945 | 1 [R] | 0 |
|
1 | ivcoa_m | isovaleryl-CoA(4-) | CHEBI:57345 | 1 [R] | 0 |
|
1 | co2_m | carbon dioxide | CHEBI:16526 | 1 [R] | 0 |