Universal:OIVD2
- _2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate)
-
coa_c + 3mob_c + nad_c ⇌ ibcoa_c + nadh_c + co2_c coa_c:-4 + 3mob_c:-1 + nad_c:-1 ⇌ ibcoa_c:-4 + nadh_c:-2 + co2_c:0
RHEA:13997
- 3-methyl-2-oxobutanoate + NAD(+) + CoA = 2-methylpropanoyl-CoA + CO2 + NADH
- View on RHEA
Properties
- Names: 3-methyl-2-oxobutanoate:NAD+ oxidoreductase (CoA-mehtylpropanoylating)[1,2], (CoA-mehtylpropanoylating)[1,2], 2-oxoisovalerate dehydrogenase[1,2], 2-oxoisovalerate dehydrogenase (acylating 3-methyl-2-oxobutanoate)[1,2], 2-oxoisovalerate dehydrogenase (acylating)[1,2], 2-oxoisovalerate dehydrogenase (acylating- 3-methyl-2-oxobutanoate)[1,2], 3-Methyl-2-oxobutanoate:NAD+ oxidoreductase[1,2], 3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)[1,2], alpha-ketoisovalerate dehydrogenase[1,2]
Linkouts
- RHEA: 13997 [0], 13998 [0], 13999 [0], 14000 [0]
- EC: 1.2.1.25 [0]
- MetaCyc Reaction: 1.2.1.25-RXN [0,1,2]
- KEGG Reaction: R01210 [0,1,2]
- seed.reaction: rxn00899 [1], rxn27481 [2]
- MetaNetX Reaction: MNXR102173 [1,2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | coa_c | coenzyme A(4-) | CHEBI:57287 | 1 [L] | 0 |
|
-1 | 3mob_c | 3-methyl-2-oxobutanoate | CHEBI:11851 | 1 [L] | 0 |
|
-1 | nad_c | NAD(1-) | CHEBI:57540 | 1 [L] | 0 |
 |
1 | ibcoa_c | isobutyryl-CoA(4-) | CHEBI:57338 | 1 [R] | 0 |
|
1 | nadh_c | NADH(2-) | CHEBI:57945 | 1 [R] | 0 |
|
1 | co2_c | carbon dioxide | CHEBI:16526 | 1 [R] | 0 |