Universal:PDHe2r
- Pyruvate dehydrogenase E2 reaction
-
adhlam_m + coa_m ⇌ accoa_m + dhlam_m adhlam_m:0 + coa_m:-4 ⇌ accoa_m:-4 + dhlam_m:0
RHEA:33151
- (R)-dihydrolipoamide + acetyl-CoA = (R)-S(6)-acetyldihydrolipoamide + CoA
- View on RHEA
Properties
- Names: acetyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-acetyltransferase[1,2,3,4,5], Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex[1,2,3,4,5], dihydrolipoamide acetyltransferase component of PDH complex[1,2,3,4,5], pyruvate dehydrogenase (dihydrolipoamide acetyltransferase)[1,2,3,4,5], pyruvate dehydrogenase (dihydrolipoamide) reversible[1,2,3,4,5], DIHYDLIPACETRANS-RXN.c[2], Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial[3], DIHYDLIPACETRANS-RXN.e[5]
Linkouts
- RHEA: 33151 [0], 33152 [0], 33153 [0], 33154 [0]
- EC: 2.3.1.12 [0]
- MetaCyc Reaction: DIHYDLIPACETRANS-RXN [0,1,2,3,4,5]
- seed.reaction: rxn01871 [1], rxn19485 [2], rxn30149 [3], rxn34255 [4], rxn38077 [5]
- KEGG Reaction: R02569 [1,2,3,4,5]
- MetaNetX Reaction: MNXR102430 [1,2,3,4,5], MNXR107584 [1,2,3,4,5]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
1 | accoa_m | acetyl-CoA(4-) | CHEBI:57288 | 1 [L] | 0 |
|
1 | dhlam_m | (R)-dihydrolipoamide | CHEBI:43711 | 1 [L] | 0 |
 |
-1 | adhlam_m | (R)-S(6)-acetyldihydrolipoamide | CHEBI:83096 | 1 [R] | 0 |
|
-1 | coa_m | coenzyme A(4-) | CHEBI:57287 | 1 [R] | 0 |
In BiGGr Models
| Organism | Model |
|---|---|
| Phaeodactylum tricornutum CCAP 1055/1 | iLB1027_lipid |