Universal:PDHm
- R_pyruvate_dehydrogenase
-
coa_m + nad_m + pyr_m ⇌ nadh_m + accoa_m + co2_m coa_m:-4 + nad_m:-1 + pyr_m:-1 ⇌ nadh_m:-2 + accoa_m:-4 + co2_m:0
RHEA:28042
- pyruvate + NAD(+) + CoA = acetyl-CoA + CO2 + NADH
- View on RHEA
Properties
- Names: pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating)[1,2,3], pyruvate dehydrogenase[1,2,3], pyruvate dehydrogenase complex[1,2,3], PYRUVDEH-RXN.d[2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | coa_m | coenzyme A(4-) | CHEBI:57287 | 1 [L] | 0 |
|
-1 | nad_m | NAD(1-) | CHEBI:57540 | 1 [L] | 0 |
|
-1 | pyr_m | pyruvate | CHEBI:15361 | 1 [L] | 0 |
 |
1 | nadh_m | NADH(2-) | CHEBI:57945 | 1 [R] | 0 |
|
1 | accoa_m | acetyl-CoA(4-) | CHEBI:57288 | 1 [R] | 0 |
|
1 | co2_m | carbon dioxide | CHEBI:16526 | 1 [R] | 0 |