MTHFR2 in iEcDH1_1363
- 5,10-methylenetetrahydrofolate reductase (NADH)
- 2 h_c:1 + mlthf_c:-2 + nadh_c:-2 → 5mthf_c:-1 + nad_c:-1
- Bounds: (0.0, 1000.0)
- Universal Reaction: MTHFR2
RHEA:19821
- (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADH + H(+)
- View on RHEA
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
| -2 | h_c:1 | hydron | CHEBI:15378 | - | - | |
| -1 | mlthf_c:-2 | (6R)-5,10-methylenetetrahydrofolate(2-) | CHEBI:15636 | 1 [R] | 0 | |
| -1 | nadh_c:-2 | NADH(2-) | CHEBI:57945 | 1 [R] | 0 | |
| 1 | 5mthf_c:-1 | (6S)-5-methyltetrahydrofolate(1−) | BIGGR:5mthf:-1 | 1 [L] | 0 | |
| 1 | nad_c:-1 | NAD(1-) | CHEBI:57540 | 1 [L] | 0 | |