RHEA:11172
- (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine
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Properties
- Names: 5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase[1,2], 5-methionine synthase[1,2], 5-methyltetrahydrofolate--homocysteine S-methyltransferase[1,2], 5-methyltetrahydrofolate--homocysteine s-methyltransferase[1,2], 5-methyltetrahydrofolate-homocysteine S-methyltransferase[1,2], 5-methyltetrahydrofolate-homocysteine transmethylase[1,2], 5-methyltetrahydrofolate:L-homocysteine S-methyltransferase[1,2], B12 N5-methyltetrahydrofolate homocysteine methyltransferase[1,2], MetH[1,2], N-methyltetrahydrofolate:L-homocysteine methyltransferase[1,2], N5-methyltetrahydrofolate methyltransferase[1,2], N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase[1,2], N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase[1,2], cobalamin-dependent methionine synthase[1,2], methionine synthase[1,2], methionine synthase (cobalamin-dependent)[1,2], methionine synthase reversible[1,2], methyltetrahydrofolate-homocysteine vitamin B12 methyltransferase[1,2], tetrahydrofolate methyltransferase[1,2], tetrahydropteroylglutamate methyltransferase[1,2], tetrahydropteroylglutamic methyltransferase[1,2], vitamin B12 methyltransferase[1,2]
Linkouts
- RHEA: 11172 [0], 11173 [0], 11174 [0], 11175 [0]
- GO: 0008705 [0]
- EC: 2.1.1.13 [0]
- MetaCyc Reaction: HOMOCYSMETB12-RXN [0,1,2]
- KEGG Reaction: R00946 [0,1,2]
- seed.reaction: rxn00693 [1], rxn32052 [2]
- MetaNetX Reaction: MNXR139019 [1,2], MNXR141853 [1,2]
Reaction Participants
| Stoich. | BiGG ID | Name | Reference | x [side] | Compartment | |
|---|---|---|---|---|---|---|
 |
-1 | 5mthf_c:-2 | (6S)-5-methyltetrahydrofolate(2-) | CHEBI:18608 | 1 [L] | 0 |
|
-1 | hcys__L_c:0 | L-homocysteine zwitterion | CHEBI:58199 | 1 [L] | 0 |
 |
1 | met__L_c:0 | L-methionine zwitterion | CHEBI:57844 | 1 [R] | 0 |
|
1 | thf_c:-2 | (6S)-5,6,7,8-tetrahydrofolate(2-) | CHEBI:57453 | 1 [R] | 0 |
